Zobrazeno 1 - 8
of 8
pro vyhledávání: '"A L, Beetsma"'
Autor:
Andrew P. Waters, Dina Vlachou, Gabrielle Margos, Annette L. Beetsma, Robert E. Sinden, Inga Siden-Kiamos, Christos Louis
We have developed an in vitro culture system for early sporogonic stages of Plasmodium berghei, which can be used to study developmental events normally taking place in the midgut of an infected mosquito. These include penetration of insect cells by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adaf5b188c7a5e02fcb12cd5b15445e
https://ora.ox.ac.uk/objects/uuid:b31a8848-131e-4af5-8968-1e44209a51ef
https://ora.ox.ac.uk/objects/uuid:b31a8848-131e-4af5-8968-1e44209a51ef
Autor:
Alan W. Thomas, Jason M. Mwenda, Hastings Ozwara, Clemens H. M. Kocken, Annemarie van der Wel, Annette L. Beetsma
Publikováno v:
Infection and Immunity. 70:655-660
Transfection technology for malaria parasites provides a valuable tool for analyzing gene function and correlating genotype with phenotype. Transfection models are even more valuable when appropriate animal models are available in addition to complet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452d40c386d2465db21ef43105ca903e
https://doi.org/10.1128/iai.70.2.655-660.2002
https://doi.org/10.1128/iai.70.2.655-660.2002
Autor:
Jo Hooghof, Jai Ramesar, Rosalina M.L. van Spaendonk, Chris J. Janse, Annette L. Beetsma, Auke van Wigcheren, Wijnand Eling, Andrew P. Waters, Geert-Jan van Gemert
Publikováno v:
Journal of Biological Chemistry, 276(25), 22638-22647. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 276, 22638-22647
Journal of Biological Chemistry, 276, pp. 22638-22647
Van Spaendonk, R M L, Ramesar, J, Van Wigcheren, A, Eling, W, Beetsma, A L, Van Gemert, G J, Hooghof, J, Janse, C J & Waters, A P 2001, ' Functional Equivalence of Structurally Distinct Ribosomes in the Malaria Parasite, Plasmodium berghei ', Journal of Biological Chemistry, vol. 276, no. 25, pp. 22638-22647 . https://doi.org/10.1074/jbc.M101234200
Journal of Biological Chemistry, 276, 22638-22647
Journal of Biological Chemistry, 276, pp. 22638-22647
Van Spaendonk, R M L, Ramesar, J, Van Wigcheren, A, Eling, W, Beetsma, A L, Van Gemert, G J, Hooghof, J, Janse, C J & Waters, A P 2001, ' Functional Equivalence of Structurally Distinct Ribosomes in the Malaria Parasite, Plasmodium berghei ', Journal of Biological Chemistry, vol. 276, no. 25, pp. 22638-22647 . https://doi.org/10.1074/jbc.M101234200
Unlike most eukaryotes, many apicomplexan parasites contain only a few unlinked copies of ribosomal RNA (rRNA) genes. Based on stage-specific expression of these genes and structural differences among the rRNA molecules it has been suggested that Pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03dc1be0102e9829cd1565dbcec99c8
https://doi.org/10.1074/jbc.M101234200
https://doi.org/10.1074/jbc.M101234200
Autor:
Kai Wengelnik, Annette L. Beetsma, Fotis C. Kafatos, Robert E. Sinden, Johannes T. Dessens, George Dimopoulos, Andrea Crisanti
Publikováno v:
The EMBO Journal. 18:6221-6227
The malaria parasite suffers severe population losses as it passes through its mosquito vector. Contributing factors are the essential but highly constrained developmental transitions that the parasite undergoes in the mosquito midgut, combined with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f103f8cbb1001610a74cd953f801b1c7
https://doi.org/10.1093/emboj/18.22.6221
https://doi.org/10.1093/emboj/18.22.6221
Publikováno v:
Methods in molecular medicine. 72
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64bbe69c2840a876b76107de7d2606c9
https://pubmed.ncbi.nlm.nih.gov/12125122
https://pubmed.ncbi.nlm.nih.gov/12125122
Publikováno v:
Science (New York, N.Y.). 295(5555)
Methods for reproducible in vitro development of the mosquito stages of malaria parasites to produce infective sporozoites have been elusive for over 40 years. We have cultured gametocytes ofPlasmodium bergheithrough to infectious sporozoites with ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d83b88f6669e9d2ef5a8a0be688232
https://pubmed.ncbi.nlm.nih.gov/11809973
https://pubmed.ncbi.nlm.nih.gov/11809973
P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions
Autor:
Pietro Lupetti, Gabriele Margos, Chris J. Janse, Maria del Carmen Rodriguez, George Dimopoulos, Geoffrey Butcher, Marianna Karras, Tania F. de Koning-Ward, Annette L. Beetsma, Ana M. Tomás, Leo H.M. van Lin, Jacqui Mendoza, Andrew P. Waters, Ria Sinha, Robert E. Sinden, Fotis C. Kafatos, Ariadne Hager
Publikováno v:
The EMBO journal. 20(15)
The ookinete surface proteins (P25 and P28) are proven antimalarial transmission-blocking vaccine targets, yet their biological functions are unknown. By using single (Sko) and double gene knock-out (Dko) Plasmodium berghei parasites, we show that P2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c8db1f4eed41dec8aa77abfe33a1c2
http://ora.ox.ac.uk/objects/uuid:c6c279e5-a6e4-4bf8-b579-5c34f9c2127c
http://ora.ox.ac.uk/objects/uuid:c6c279e5-a6e4-4bf8-b579-5c34f9c2127c