Zobrazeno 1 - 10
of 295
pro vyhledávání: '"A Kitmitto"'
Autor:
Bodour S. Rajab, Sarah Kassab, Connor D. Stonall, Hussam Daghistani, Stephen Gibbons, Mamas Mamas, David Smith, Aleksandr Mironov, Zainab AlBalawi, Yin Hua Zhang, Florence Baudoin, Min Zi, Sukhpal Prehar, Elizabeth J. Cartwright, Ashraf Kitmitto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Mitochondrial dysfunction is a feature of type I and type II diabetes, but there is a lack of consistency between reports and links to disease development. We aimed to investigate if mitochondrial structure–function remodelling occurs in t
Externí odkaz:
https://doaj.org/article/bde8520cc3e14e259933a31d61e012ec
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
A pathophysiological consequence of both type 1 and 2 diabetes is remodelling of the myocardium leading to the loss of left ventricular pump function and ultimately heart failure (HF). Abnormal cardiac bioenergetics associated with mitochondrial dysf
Externí odkaz:
https://doaj.org/article/c600771a3c0d419fabbc2ee84fa09942
Autor:
Nora Linscheid, Sunil Jit R. J. Logantha, Pi Camilla Poulsen, Shanzhuo Zhang, Maren Schrölkamp, Kristoffer Lihme Egerod, Jonatan James Thompson, Ashraf Kitmitto, Gina Galli, Martin J. Humphries, Henggui Zhang, Tune H. Pers, Jesper Velgaard Olsen, Mark Boyett, Alicia Lundby
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
The sinus node generates rhythmic heartbeat but the molecular basis of pacemaking is still under debate. Here, the authors combine quantitative proteomics and single-nucleus transcriptomics to characterize the molecular composition of the sinus node
Externí odkaz:
https://doaj.org/article/8be1ba1976464a228f6bde3e4a31e04c
Autor:
Pinali, Christian, Kitmitto, Ashraf
Publikováno v:
In Journal of Molecular and Cellular Cardiology November 2014 76:1-11
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:4-5
Autor:
Pia Camila Morales Araya, Yulia Suciati Kohar, Sukhpal Prehar, Min Zi, Elizabeth Cartwright, Ashraf Kitmitto, Delvac Oceandy
Publikováno v:
Basic science.
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 8, p e1005714 (2017)
Intracellular calcium cycling is a vital component of cardiac excitation-contraction coupling. The key structures responsible for controlling calcium dynamics are the cell membrane (comprising the surface sarcolemma and transverse-tubules), the intra
Externí odkaz:
https://doaj.org/article/63f6e3d956cf40498156d469bbba5bba
Autor:
Christian Pinali, Nadim Malik, J. Bernard Davenport, Laurence J. Allan, Lucy Murfitt, Mohammad M. Iqbal, Mark R. Boyett, Elizabeth J. Wright, Rachel Walker, Yu Zhang, Halina Dobryznski, Cathy M. Holt, Ashraf Kitmitto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 5 (2017)
BackgroundHeart failure is a common secondary complication following a myocardial infarction (MI), characterized by impaired cardiac contraction and t‐tubule (t‐t) loss. However, post‐MI nano‐scale morphological changes to the remaining t‐t
Externí odkaz:
https://doaj.org/article/78d74663cfa54af9bef238c7a61d8829
Akademický článek
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Publikováno v:
Journal of Muscle Research and Cell Motility
Kitmitto, A, Baudoin, F & Cartwright, E J 2019, ' Cardiomyocyte damage control in heart failure and the role of the sarcolemma ', Journal of Muscle Research and Cell Motility . https://doi.org/10.1007/s10974-019-09539-5
Kitmitto, A, Baudoin, F & Cartwright, E J 2019, ' Cardiomyocyte damage control in heart failure and the role of the sarcolemma ', Journal of Muscle Research and Cell Motility . https://doi.org/10.1007/s10974-019-09539-5
The cardiomyocyte plasma membrane, termed the sarcolemma, is fundamental for regulating a myriad of cellular processes. For example, the structural integrity of the cardiomyocyte sarcolemma is essential for mediating cardiac contraction by forming mi