Zobrazeno 1 - 10
of 23
pro vyhledávání: '"A Katherine Tan"'
Autor:
A Katherine Tan, Aurelie Henry, Nicolas Goffart, Christophe Poulet, Jacqueline A. Sluijs, Elly M. Hol, Vincent Bours, Pierre A. Robe
Publikováno v:
Cells, Vol 13, Iss 22, p 1883 (2024)
Background: Previous works have shown that the expression of Class-II-Transactivator (CIITA) in tumor cells reduces the growth of glioblastoma (GB) in animal models, but immune effects cannot solely explain this. Here, we searched for immune-independ
Externí odkaz:
https://doaj.org/article/82a80617d9104313a582ab179e7f90ca
Autor:
Ruwandi Kariyawasam, Rachel Lau, Eric Shao, Katherine Tan, Adrienne Showler, Filip Ralevski, Samir N. Patel, Andrea K. Boggild
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 4, Pp 812-819 (2022)
Single-nucleotide polymorphisms at several loci have been correlated with Plasmodium falciparum drug resistance. We examined the prevalence of resistance markers in P. falciparum from imported malaria cases in Canada during 3 time periods, 2008–200
Externí odkaz:
https://doaj.org/article/dc1ccae83d884ed8ae7954414f47c482
Autor:
W. Katherine Tan, Brian D. Segal, Melissa D. Curtis, Shrujal S. Baxi, William B. Capra, Elizabeth Garrett-Mayer, Brian P. Hobbs, David S. Hong, Rebecca A. Hubbard, Jiawen Zhu, Somnath Sarkar, Meghna Samant
Publikováno v:
Contemporary Clinical Trials Communications, Vol 30, Iss , Pp 101000- (2022)
Background: Hybrid controlled trials with real-world data (RWD), where the control arm is composed of both trial and real-world patients, could facilitate research when the feasibility of randomized controlled trials (RCTs) is challenging and single-
Externí odkaz:
https://doaj.org/article/55c43bce2efa4cd8a8dc5818e59052f3
Autor:
Sanhita Sengupta, Ives Ntambwe, Katherine Tan, Qixing Liang, David Paulucci, Emily Castellanos, Joseph Fiore, Stephen Lane, Mariann Micsinai Balan, Kalyanee Viraswami‐Apanna, Venkat Sethuraman, Meghna Samant, Ram Tiwari
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:867-877
This proof-of-concept study retrospectively assessed the feasibility of applying a hybrid control arm design to a completed phase 3 randomized controlled trial (RCT; CheckMate-057) in advanced non-small cell lung cancer using a real-world data (RWD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2249d9de52620f583f72075ee59d46e
https://doi.org/10.1002/cpt.2841
https://doi.org/10.1002/cpt.2841
Autor:
Michael L. Waskom, Katherine Tan, Holly Wiberg, Aaron B. Cohen, Brett Wittmershaus, Will Shapiro
ObjectiveMachine learning has the potential to increase the scale of real-world data curated from electronic health records, but maintaining a high standard of data quality is important to avoid biasing downstream analyses. To increase scale without
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea784d8f2532975bca5b0af932e14f27
https://doi.org/10.1101/2023.03.06.23286770
https://doi.org/10.1101/2023.03.06.23286770
Autor:
Nadège, Dubois, Sharon, Berendsen, Katherine, Tan, Laurent, Schoysmans, Wim, Spliet, Tatjana, Seute, Vincent, Bours, Pierre A, Robe
Publikováno v:
International Journal of Oncology. 61
The copy number and mRNA expression of STAT5b were assessed in samples from the TCGA repository of glioblastomas (GBM). The activation of this transcription factor was analyzed on tissue microarrays comprising 392 WHO 2016 GBM samples from our clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7e8e399be09601836f1c7f5a55179b
https://doi.org/10.3892/ijo.2022.5414
https://doi.org/10.3892/ijo.2022.5414
Autor:
William B. Capra, Brian D. Segal, Lawrence Bellomo, Katherine Tan, Rebecca A. Miksad, Carrie Bennette, Nate Nussbaum, Jonathan Bryan, Aracelis Z. Torres, Melisa Tucker, Melissa D. Curtis
Publikováno v:
Clinical Pharmacology & Therapeutics. 111:168-178
Electronic health record (EHR)-derived real-world data (RWD) can be sourced to create external comparator cohorts to oncology clinical trials. This exploratory study assessed whether EHR-derived patient cohorts could emulate select clinical trial con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb192627eb2d1913f36f3cfce65bf19d
https://doi.org/10.1002/cpt.2351
https://doi.org/10.1002/cpt.2351
Autor:
Natalia Smith-Cortinez, A. Katherine Tan, Robert J. Stokroos, Huib Versnel, Louise V. Straatman
Publikováno v:
International Journal of Molecular Sciences. 24:7840
Sensorineural hearing loss is caused by damage to sensory hair cells and/or spiral ganglion neurons. In non-mammalian species, hair cell regeneration after damage is observed, even in adulthood. Although the neonatal mammalian cochlea carries regener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::688082c518c140ae9b6df35cc8635de2
https://doi.org/10.3390/ijms24097840
https://doi.org/10.3390/ijms24097840
Autor:
W. Katherine Tan, Patrick J. Heagerty
Publikováno v:
Biostatistics. 23:345-361
Summary Scalable and accurate identification of specific clinical outcomes has been enabled by machine-learning applied to electronic medical record systems. The development of classification models requires the collection of a complete labeled data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a91d58341cfa95dfc8b97ab48fd5f9f
https://doi.org/10.1093/biostatistics/kxaa028
https://doi.org/10.1093/biostatistics/kxaa028
Publikováno v:
Future oncology (London, England). 17(32)
Aim: To investigate real-world overall survival (rwOS) and real-world progression-free survival (rwPFS) in locally advanced/metastatic urothelial carcinoma postplatinum and postprogrammed death receptor-1/death ligand 1 inhibitors. Patients & methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f458ed07684c35b3d51d5dbe7ad689
https://pubmed.ncbi.nlm.nih.gov/34350778
https://pubmed.ncbi.nlm.nih.gov/34350778