Zobrazeno 1 - 10
of 161
pro vyhledávání: '"A K MAHAL"'
Publikováno v:
The Indian Journal of Agricultural Sciences, Vol 92, Iss 9 (2022)
Mat-type nursery having uniform growth is a prerequisite for mechanized paddy transplanting. Generally, this type of nursery is sown manually in the open field or in trays. It requires several simultaneous operations and hence is laborious and time-c
Externí odkaz:
https://doaj.org/article/ddff2e1f85754ff3996412d96b9d455a
Autor:
Thirupathi Nuligonda, Gautam Kumar, Jason W. Wang, Dinithi Rajapaksha, Ismael A. Elayan, Ramiz Demir, Neil J. Meanwell, Sherrie F. Wang, Lara K. Mahal, Alex Brown, Michael W. Meanwell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract C4ʹ-modified nucleoside analogues continue to attract global attention for their use in antiviral drug development and oligonucleotide-based therapeutics. However, current approaches to C4ʹ-modified nucleoside analogues still involve lengt
Externí odkaz:
https://doaj.org/article/d7aee5e037d04b6daf31add4ec8c4aae
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105163- (2022)
Summary: Glycosylation is ubiquitous and often dysregulated in disease. However, the regulation and functional significance of various types of glycosylation at cellular levels is hard to unravel experimentally. Multi-omics, single-cell measurements
Externí odkaz:
https://doaj.org/article/e9ca59b16a4f47679f3b402ec29b8e78
Autor:
Won-Min Song, Praveen Agrawal, Richard Von Itter, Barbara Fontanals-Cirera, Minghui Wang, Xianxiao Zhou, Lara K. Mahal, Eva Hernando, Bin Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
While the molecular profiling of melanoma progression has been extensively characterised by large-scale studies, there is still need for the comprehensive integration of such datasets. Here the authors construct predictive gene network models for pro
Externí odkaz:
https://doaj.org/article/34410138163b46d4b7214aefccddd28a
Autor:
Guillaume Bay, Conard Lee, Chiliang Chen, Navreet K. Mahal, Michael J. Castellano, Kirsten S. Hofmockel, Larry J. Halverson
Publikováno v:
mSystems, Vol 6, Iss 5 (2021)
ABSTRACT Cropping system diversity provides yield benefits that may result from shifts in the composition of root-associated bacterial and fungal communities, which either enhance nutrient availability or limit nutrient loss. We investigated whether
Externí odkaz:
https://doaj.org/article/08da7fefe05d4f468fafa38d29b9675c
Autor:
Fatima Al-Gawhari, Raff ah K Mahal
Publikováno v:
INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY. 13:322-334
Oral and intravenous dosing of the second-generation antifungal drug voriconazole (VCZ), with its wide range of antifungal action, is commercially accessible. Visual and hepatic problems might occur when VCZ is used in large doses. Voriconazole SLNs
Autor:
Fatima . Al-Gawhari, Raffah K. Mahal
Publikováno v:
INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY. 12:1702-1716
As a well-known oral and intravenous antifungal, voriconazole (VRN) has an extensive history of usage in the medical field. Solid lipid nanoparticles (SLNs) have been produced to treat ocular fungal keratitis in the eye. A 32Box-behnken design was us
Publikováno v:
ACS Central Science. 8:1527-1536
Chemical biology has revealed the importance of sialic acids as a major signal in physiology and disease. The terminal modification α-2,6-sialic acid is controlled by the enzymes ST6GAL1 and ST6GAL2. Dysregulation of this glycan impacts immunologica
Autor:
Duong T. Bui, Zhixiong Li, Pavel I. Kitov, Ling Han, Elena N. Kitova, Marlène Fortier, Camille Fuselier, Philippine Granger Joly de Boissel, David Chatenet, Nicolas Doucet, Stephen M. Tompkins, Yves St-Pierre, Lara K. Mahal, John S. Klassen
Publikováno v:
ACS Central Science. 8:963-974
Electrospray ionization mass spectrometry (ESI-MS) is a powerful label-free assay for detecting noncovalent biomolecular complexes
Autor:
Chang Wang, Rebekah Honce, Mirella Salvatore, Daniela Chow, Davide Randazzo, Jianjun Yang, Nicholas M. Twells, Lara K. Mahal, Stacey Schultz-Cherry, Elodie Ghedin
Publikováno v:
Journal of Virology.
During replication, the influenza virus generates genetically defective viruses. These are found in natural infections as part of the virus population within the infected host.