Zobrazeno 1 - 10
of 1 610
pro vyhledávání: '"A K MAHAL"'
Autor:
Thirupathi Nuligonda, Gautam Kumar, Jason W. Wang, Dinithi Rajapaksha, Ismael A. Elayan, Ramiz Demir, Neil J. Meanwell, Sherrie F. Wang, Lara K. Mahal, Alex Brown, Michael W. Meanwell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract C4ʹ-modified nucleoside analogues continue to attract global attention for their use in antiviral drug development and oligonucleotide-based therapeutics. However, current approaches to C4ʹ-modified nucleoside analogues still involve lengt
Externí odkaz:
https://doaj.org/article/d7aee5e037d04b6daf31add4ec8c4aae
Autor:
Daniel W. Heindel, Dania M. Figueroa Acosta, Marisa Goff, Clauvis Kunkeng Yengo, Muzafar Jan, Xiaomei Liu, Xiao-Hong Wang, Mariya I. Petrova, Mo Zhang, Manish Sagar, Phillip Barnette, Shilpi Pandey, Ann J. Hessell, Kun-Wei Chan, Xiang-Peng Kong, Benjamin K. Chen, Lara K. Mahal, Barbara A. Bensing, Catarina E. Hioe
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110390- (2024)
Summary: Bacteria dysbiosis and its accompanying inflammation or compromised mucosal integrity is associated with an increased risk of HIV-1 transmission. However, HIV-1 may also bind bacteria or bacterial products to impact infectivity and transmiss
Externí odkaz:
https://doaj.org/article/e5305c3f335e45a9a5819c9e033eed91
Autor:
Edward N. Schmidt, Dimitra Lamprinaki, Kelli A. McCord, Maju Joe, Mirat Sojitra, Ayk Waldow, Jasmine Nguyen, John Monyror, Elena N. Kitova, Fahima Mozaneh, Xue Yan Guo, Jaesoo Jung, Jhon R. Enterina, Gour C. Daskhan, Ling Han, Amanda R. Krysler, Christopher R. Cromwell, Basil P. Hubbard, Lori J. West, Marianne Kulka, Simonetta Sipione, John S. Klassen, Ratmir Derda, Todd L. Lowary, Lara K. Mahal, Meghan R. Riddell, Matthew S. Macauley
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Immunomodulatory Siglecs are controlled by their glycoprotein and glycolipid ligands. Siglec-glycolipid interactions are often studied outside the context of a lipid bilayer, missing the complex behaviors of glycolipids in a membrane. Throug
Externí odkaz:
https://doaj.org/article/1b849c2f9a814c4e9507f12b5f5f0d43
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105163- (2022)
Summary: Glycosylation is ubiquitous and often dysregulated in disease. However, the regulation and functional significance of various types of glycosylation at cellular levels is hard to unravel experimentally. Multi-omics, single-cell measurements
Externí odkaz:
https://doaj.org/article/e9ca59b16a4f47679f3b402ec29b8e78
Publikováno v:
The Indian Journal of Agricultural Sciences, Vol 92, Iss 9 (2022)
Mat-type nursery having uniform growth is a prerequisite for mechanized paddy transplanting. Generally, this type of nursery is sown manually in the open field or in trays. It requires several simultaneous operations and hence is laborious and time-c
Externí odkaz:
https://doaj.org/article/ddff2e1f85754ff3996412d96b9d455a
Autor:
Won-Min Song, Praveen Agrawal, Richard Von Itter, Barbara Fontanals-Cirera, Minghui Wang, Xianxiao Zhou, Lara K. Mahal, Eva Hernando, Bin Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
While the molecular profiling of melanoma progression has been extensively characterised by large-scale studies, there is still need for the comprehensive integration of such datasets. Here the authors construct predictive gene network models for pro
Externí odkaz:
https://doaj.org/article/34410138163b46d4b7214aefccddd28a
Publikováno v:
Вестник Воронежского государственного университета. Серия: Лингвистика и межкультурная коммуникация.
Autor:
Guillaume Bay, Conard Lee, Chiliang Chen, Navreet K. Mahal, Michael J. Castellano, Kirsten S. Hofmockel, Larry J. Halverson
Publikováno v:
mSystems, Vol 6, Iss 5 (2021)
ABSTRACT Cropping system diversity provides yield benefits that may result from shifts in the composition of root-associated bacterial and fungal communities, which either enhance nutrient availability or limit nutrient loss. We investigated whether
Externí odkaz:
https://doaj.org/article/08da7fefe05d4f468fafa38d29b9675c
Autor:
Fatima Al-Gawhari, Raff ah K Mahal
Publikováno v:
INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY. 13:322-334
Oral and intravenous dosing of the second-generation antifungal drug voriconazole (VCZ), with its wide range of antifungal action, is commercially accessible. Visual and hepatic problems might occur when VCZ is used in large doses. Voriconazole SLNs
Autor:
Fatima . Al-Gawhari, Raffah K. Mahal
Publikováno v:
INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY. 12:1702-1716
As a well-known oral and intravenous antifungal, voriconazole (VRN) has an extensive history of usage in the medical field. Solid lipid nanoparticles (SLNs) have been produced to treat ocular fungal keratitis in the eye. A 32Box-behnken design was us