Zobrazeno 1 - 10
of 12
pro vyhledávání: '"A K Lofquist"'
Publikováno v:
Molecular and Cellular Biology. 17:3898-3906
Monocyte adherence results in the rapid transcriptional activation and mRNA stabilization of numerous mediators of inflammation and tissue repair. While the enhancer and promoter elements associated with transcriptional activation have been studied,
Publikováno v:
The Journal of Immunology. 155:4467-4475
The epithelium-associated tissue distribution of the intracellular IL-1R antagonist (icIL-1Ra) suggests that it functions as a novel regulatory molecule for IL-1 in somatic tissues. We examined the role of the icIL-1Ra in IL-1 beta-induced responses
Publikováno v:
Molecular and Cellular Biology. 15:1737-1746
We identified I kappa B alpha/MAD-3 as an immediate-early gene in human monocytes that is expressed in response to a variety of signals, including adhesion, lipopolysaccharide, and phorbol myristate acetate. Within 5 min of monocyte adhesion, the lev
Publikováno v:
Journal of Biological Chemistry. 267:24601-24610
A nuclear extract from Acanthamoeba castellanii which contains all of the components necessary for specific transcription of a 5 S RNA gene was separated into fractions required for specific transcription initiation and an additional fraction needed
Publikováno v:
Journal of leukocyte biology. 67(2)
Monocyte adhesion resulted in rapid tyrosine phosphorylation and subsequent cytokine mRNA induction. The objective of this study was to determine the role of specific tyrosine phosphorylation events, particularly those involving members of the MAP ki
Autor:
L F, Lee, C C, Schuerer-Maly, A K, Lofquist, C, van Haaften-Day, J P, Ting, C M, White, B K, Martin, J S, Haskill
Publikováno v:
Cancer research. 56(6)
Taxol is important in the treatment of both primary and drug-resistant ovarian cancer. Although Taxol is known to stabilize microtubules and block cell mitosis, the effectiveness of this drug exceeds that of other antimitotic agents, suggesting it ma
Autor:
J M, Watson, A K, Lofquist, C A, Rinehart, J C, Olsen, S S, Makarov, D G, Kaufman, J S, Haskill
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(9)
The epithelium-associated tissue distribution of the intracellular IL-1R antagonist (icIL-1Ra) suggests that it functions as a novel regulatory molecule for IL-1 in somatic tissues. We examined the role of the icIL-1Ra in IL-1 beta-induced responses
Publikováno v:
Science (New York, N.Y.). 270(5234)
Glucocorticoids are potent immunosuppressive drugs, but their mechanism is poorly understood. Nuclear factor kappa B (NF-kappa B), a regulator of immune system and inflammation genes, may be a target for glucocorticoid-mediated immunosuppression. The
Publikováno v:
Biochemical Society transactions. 23(3)
460 Adhesion and direct integrin engagement differentially regulate gene transcription, transcript stabilization and translation K. Mondal*, A. K. Lofquistt, J. M. Watsont, J. S. Morrist, L. K. Pricet and J. S. Haskill*t$ *Department of Microbiology
Publikováno v:
Molecular and cellular biology. 15(3)
We identified I kappa B alpha/MAD-3 as an immediate-early gene in human monocytes that is expressed in response to a variety of signals, including adhesion, lipopolysaccharide, and phorbol myristate acetate. Within 5 min of monocyte adhesion, the lev