Zobrazeno 1 - 10
of 23
pro vyhledávání: '"A K H, Robertson"'
Autor:
Brooke L. McNeil, Andrew K. H. Robertson, Winnie Fu, Hua Yang, Cornelia Hoehr, Caterina F. Ramogida, Paul Schaffer
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-18 (2021)
Abstract Background Lead-212 (212Pb, t1/2 = 10.6 h) and lead-203 (203Pb, t1/2 = 51.9 h) are an element-equivalent, or a matched theranostic radioisotope pair that show great potential for application in targeted radionuclide therapy (TRT) and single-
Externí odkaz:
https://doaj.org/article/583f69d5405e48318767c159437bbcf6
Autor:
Caterina F. Ramogida, Andrew K. H. Robertson, Una Jermilova, Chengcheng Zhang, Hua Yang, Peter Kunz, Jens Lassen, Ivica Bratanovic, Victoria Brown, Lily Southcott, Cristina Rodríguez-Rodríguez, Valery Radchenko, François Bénard, Chris Orvig, Paul Schaffer
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-20 (2019)
Abstract Background Actinium-225 (225Ac, t1/2 = 9.9 d) is a promising candidate radionuclide for use in targeted alpha therapy (TAT), though the currently limited global supply has hindered the development of a suitable Ac-chelating ligand and 225Ac-
Externí odkaz:
https://doaj.org/article/c0bdf4239e5f40f0b278e347743bcfe5
Autor:
Andrew K. H. Robertson, Randy Perron, Patrick Causey, Stefan K. Zeisler, Valery Radchenko, Hua Yang, Denise Gendron, Paul Schaffer, Brooke McNeil
Publikováno v:
Inorganic Chemistry. 59:12156-12165
Recent clinical results have demonstrated remarkable treatment responses of late-stage cancer patients when treated with alpha-emitting radionuclides such as actinium-225 (225Ac). The resulting intense global effort to produce greater quantities of 2
Autor:
Chris Orvig, Paul Schaffer, Xiaozhu Wang, Valery Radchenko, Andrew K. H. Robertson, Lily Li, Kuo-Shyan Lin, Julie Rousseau, Francois Benard, María de Guadalupe Jaraquemada-Peláez
Publikováno v:
Bioconjugate Chemistry. 32:1348-1363
Herein, we present the syntheses and characterization of a new undecadendate chelator, H4py4pa, and its bifunctional analog H4py4pa-phenyl-NCS, conjugated to the monoclonal antibody, Trastuzumab, which targets the HER2+ cancer. H4py4pa possesses exce
Autor:
Cornelia Hoehr, Paul Schaffer, Hua Yang, Andrew K. H. Robertson, Caterina F. Ramogida, Winnie Fu, Brooke McNeil
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-18 (2021)
Background Lead-212 (212Pb, t1/2 = 10.6 h) and lead-203 (203Pb, t1/2 = 51.9 h) are an element-equivalent, or a matched theranostic radioisotope pair that show great potential for application in targeted radionuclide therapy (TRT) and single-photon em
Autor:
Brooke L, McNeil, Andrew K H, Robertson, Winnie, Fu, Hua, Yang, Cornelia, Hoehr, Caterina F, Ramogida, Paul, Schaffer
Publikováno v:
EJNMMI Radiopharmacy and Chemistry
Background Lead-212 (212Pb, t1/2 = 10.6 h) and lead-203 (203Pb, t1/2 = 51.9 h) are an element-equivalent, or a matched theranostic radioisotope pair that show great potential for application in targeted radionuclide therapy (TRT) and single-photon em
Publikováno v:
Physical Review C. 102
Thorium targets were irradiated with 438-MeV protons, resulting in spallation and high-energy fission reactions. The measured production cross sections of 38 nuclides in the mass range 83 to 233 are reported. These cross-section data are useful for v
Autor:
Laura Lambert, Jens Lassen, Jason Crawford, Valery Radchenko, Paul Schaffer, Thomas J. Ruth, Corina Andreoiu, Caterina F. Ramogida, F. H. Garcia, Julia Even, Andrew K. H. Robertson, Peter Kunz
Publikováno v:
Progress in Nuclear Science and Technology, 5(0), 4-7
Autor:
Andrew K. H. Robertson, Stephan Blinder, Cristina Rodríguez-Rodríguez, Vesna Sossi, Peter Kunz, Caterina F. Ramogida, Paul Schaffer
Publikováno v:
Physics in Medicine and Biology. 62:4406-4420
Effective use of the decay chain in targeted internal radioimmunotherapy requires the retention of both and progeny isotopes at the target site. Imaging-based pharmacokinetic tests of these pharmaceuticals must therefore separately yet simultaneously
Autor:
Hua Yang, Lily Southcott, Paul Schaffer, Peter Kunz, Ivica Bratanovic, Francois Benard, Valery Radchenko, Una Jermilova, Victoria Brown, Andrew K. H. Robertson, Chengcheng Zhang, Caterina F. Ramogida, Cristina Rodríguez-Rodríguez, Chris Orvig, Jens Lassen
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-20 (2019)
EJNMMI Radiopharmacy and Chemistry
EJNMMI Radiopharmacy and Chemistry
Background Actinium-225 (225Ac, t1/2 = 9.9 d) is a promising candidate radionuclide for use in targeted alpha therapy (TAT), though the currently limited global supply has hindered the development of a suitable Ac-chelating ligand and 225Ac-radiophar