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Akademický článek

Comparative Viral Sampling in the Sinonasal Passages; Different Viruses at Different Sites

Autor: Rachel K. Goggin, Catherine A. Bennett, Ahmed Bassiouni, Seweryn Bialasiewicz, Sarah Vreugde, Peter-John Wormald, Alkis J. Psaltis

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)

Background: With the emergence of the microbiome as an important factor in health and disease in the respiratory tract standardised, validated techniques are required for its accurate characterisation. No standardised technique has been reported spec

Externí odkaz: https://doaj.org/article/248bc1c3d4c7405c90c9b2641e1cce6a

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Partial resection of the middle turbinate during endoscopic sinus surgery for chronic rhinosinusitis does not lead to an increased risk of empty nose syndrome: a cohort study of a tertiary practice

Autor: Neil C.-W. Tan, Rachel K. Goggin, Peter-John Wormald, Alkis J. Psaltis

Publikováno v: International Forum of Allergy & Rhinology. 8:959-963

Background The treatment of the middle turbinate (MT) during endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) remains a contentious issue with arguments both for and against its resection. The purpose of this study was to examine the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfab7708552c3e38fbd7459f3d62835f
https://doi.org/10.1002/alr.22127

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Simultaneous Modeling of Biomarker and Toxicity Response Predicted Optimal Regimen of Guadecitabine (SGI-110) in Myeloid Malignancies

Autor: Hagop M. Kantarjian, Xiang Yao Su, Mohammad Azab, James N. Lowder, Cong Xu, Pietro Taverna, Timothy K. Goggin, Aram Oganesian

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology. 6:712-718

Guadecitabine (SGI-110) is a novel next-generation hypomethylating agent (HMA) administered as s.c. injection with extended decitabine exposure. Dose/exposure-response analyses of longitudinal measures of long interspersed nucleotide element-1 (LINE-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc16ecb5eabaed09767feb7421d1827a
https://doi.org/10.1002/psp4.12248

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Population pharmacokinetics and pharmacodynamics of BYL719, a phosphoinositide 3-kinase antagonist, in adult patients with advanced solid malignancies

Autor: Annamaria Jakab, Timothy K. Goggin, Cornelia Quadt, Markus Boehm, Stefan De Buck, Dejan Juric, Douglas Bootle

Publikováno v: British Journal of Clinical Pharmacology. 78:543-555

Aims The aim was to characterize the population pharmacokinetics of BYL719 in cancer patients and assess the time course of tumour response in relation to drug exposure and dosing schedule. Methods Plasma samples and longitudinal tumour size measurem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5695a0e4295430267de3e301d0c07fac
https://doi.org/10.1111/bcp.12378

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Colloidal silver: a novel treatment forStaphylococcus aureusbiofilms?

Autor: Rachel K. Goggin, Camille Jardeleza, Peter-John Wormald, Sarah Vreugde

Publikováno v: International Forum of Allergy & Rhinology. 4:171-175

Background Colloidal silver is an alternative medicine consisting of silver particles suspended in water. After using this solution as a nasal spray, the symptoms of a previously recalcitrant Staphylococcus aureus (S. aureus)-infected chronic rhinosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::510794f9c6ab22294876e963024273c7
https://doi.org/10.1002/alr.21259

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