Zobrazeno 1 - 10
of 11
pro vyhledávání: '"A K, Wensky"'
Autor:
Bruce S. Schneider, Evgenij Evdokimov, Larisa Rudenko, Cheng-Hong Wei, Phillip J. Snoy, Allen K. Wensky, Jeff Jones, Judith Arcidiacono, Mark H. Lee, Keith Wonnacott
Publikováno v:
Xenotransplantation. 17:329-337
The use of xenogeneic porcine pancreatic islets has been shown to be a potentially promising alternative to using human allogeneic islets to treat insulin-dependent type 1 diabetes (T1D). This article provides an overview of the existing FDA regulato
Autor:
Allen K. Wensky, Maria Cecilia Garibaldi Marcondes, Jo-Ann Latkowski, Juan J. Lafaille, Glaucia C. Furtado, Julia Tsai
Publikováno v:
The Journal of Immunology. 181:4648-4655
Strong evidence supports that CNS-specific CD4+ T cells are central to the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Using a model of spontaneous EAE, we demonstrated that myelin basic protein (MBP)-speci
Autor:
Allen K. Wensky, Howard S. Fox, Glaucia C. Furtado, Maria Cecilia Garibaldi Marcondes, Maria A. Curotto de Lafaille, Juan J. Lafaille
Publikováno v:
The American Journal of Pathology. 166:1749-1760
Injuries to the central nervous system (CNS) trigger an inflammatory reaction with potentially devastating consequences. In this report we compared the characteristics of the inflammatory response on spinal cord injury (SCI) caused by a stab wound be
Autor:
Denise Manfra, David Zagzag, Shaohua Chen, Maria Cecilia Garibaldi Marcondes, Glaucia C. Furtado, Juan J. Lafaille, Allen K. Wensky, Sergio A. Lira
Publikováno v:
The Journal of Immunology. 174:1416-1423
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory disease of the CNS initiated by autoreactive CD4+ T cells. EAE classically presents with a progressive ascending paralysis and is a model of multiple sclerosis that recapitulates some
Autor:
Juan J. Lafaille, Stephanie J. Muriglan, Glaucia C. Furtado, Ying Lei, Danyvid Olivares-Villagómez, Mary Jean Sunshine, Nino Kutchukhidze, Maria A. Curotto de Lafaille, Allen K. Wensky
Publikováno v:
Journal of Experimental Medicine. 194:1349-1360
A key event in the pathogenesis of allergies is the production of antibodies of the immunoglobulin (Ig)E class. In normal individuals the levels of IgE are tightly regulated, as illustrated by the low serum IgE concentration. In addition, multiple im
Autor:
Joey L. Perez, Pavel Osten, Edward B. Ziff, Georg Köhr, Christopher Daly, Günter Giese, Torsten Wilhelm Schulz, Latika Khatri, Allen K. Wensky, Laveria M. Lee
Publikováno v:
Neuron
We studied the role of PDZ proteins GRIP, ABP, and PICK1 in GluR2 AMPA receptor trafficking. An epitope-tagged MycGluR2 subunit, when expressed in hippocampal cultured neurons, was specifically targeted to the synaptic surface. With the mutant MycGlu
Autor:
Judith A, Arcidiacono, Evgenij, Evdokimov, Mark H, Lee, Jeff, Jones, Larisa, Rudenko, Bruce, Schneider, Phillip J, Snoy, Cheng-Hong, Wei, Allen K, Wensky, Keith, Wonnacott
Publikováno v:
Xenotransplantation. 17(5)
The use of xenogeneic porcine pancreatic islets has been shown to be a potentially promising alternative to using human allogeneic islets to treat insulin-dependent type 1 diabetes (T1D). This article provides an overview of the existing FDA regulato
Autor:
G C, Furtado, D, Olivares-Villagómez, M A, Curotto de Lafaille, A K, Wensky, J A, Latkowski, J J, Lafaille
Publikováno v:
Immunological reviews. 182
Spontaneous experimental autoimmune encephalomyelitis (EAE) develops in 100% of mice harboring a monoclonal myelin basic protein (MBP)-specific CD4+ alphabeta T-cell repertoire. Monoclonality of the alphabeta T-cell repertoire can be achieved by cros
Autor:
M A, Curotto de Lafaille, S, Muriglan, M J, Sunshine, Y, Lei, N, Kutchukhidze, G C, Furtado, A K, Wensky, D, Olivares-Villagómez, J J, Lafaille
Publikováno v:
The Journal of Experimental Medicine
A key event in the pathogenesis of allergies is the production of antibodies of the immunoglobulin (Ig)E class. In normal individuals the levels of IgE are tightly regulated, as illustrated by the low serum IgE concentration. In addition, multiple im
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 167(6)
It has become increasingly apparent in studies of mutant mice and observations of disease that cytokine production by fully committed effector T cells within the Th1 and Th2 phenotype can vary within each group. This can potentially influence the typ