Zobrazeno 1 - 10
of 20
pro vyhledávání: '"A K, Tsaturian"'
Autor:
F A, Sëmin, A K, Tsaturian
Publikováno v:
Biofizika. 57(5)
A simple kinetic model of muscle contraction is suggested. The rates of cross-bridge transitions from one kinetic state to another are supposed to depend on the averaged (over ensemble of actin-bound bridges) strain. With a proper set of the strain-d
Autor:
D A, Afanas'eva, A K, Tsaturian
Publikováno v:
Biofizika. 55(5)
A mathematical model of the propagation of acoustic shear waves in muscle tissue is considered. The muscle is modelled by an incompressible transversely isotropic viscoelastic continuum with quasi-one-dimensional active tension. Two types of shear wa
Publikováno v:
Molekuliarnaia biologiia. 43(4)
The interference fine structure of the M3 reflection on the low-angle x-ray diffraction patterns of muscle fibres is used for the measurements of axial movements of myosin heads with a precision of 0.1-0.2 nm. We have measured changes in the M3 inter
Publikováno v:
Biofizika. 54(4)
A structural and kinetic model of actomyosin interaction in a contracting muscle fibre has been proposed, which is based on the assumption that the myosin molecular motor generates the force in two steps. Initially the nonstereospecifically attached
Autor:
D A, Shestakov, A K, Tsaturian
Publikováno v:
Biofizika. 51(1)
The structure of the strongly bound complex of the globular myosin head and F-actin is a key for understanding some important details of the mechanism of the actin-myosin motor. Current knowledge about the structure is based on the docking of known a
Autor:
D A, Shestakov, A K, Tsaturian
Publikováno v:
Biofizika. 43(2)
A mathematical model describing mechanical transients induced by the step length changes in skeletal muscle fibres is suggested. The model takes into account compliance of actin filaments and the cross-bridge mechanics. Two different approaches were
Autor:
A K, Tsaturian, Iu G, Iakimova
Publikováno v:
Biofizika. 40(3)
A mathematical model of an actin filament sliding along myosin-coated surface in the in vitro motility assay is considered. The frontal end of the filament is supposed to be affected by a random Brownian force. The relation between the surface densit
Autor:
O N, Vershintskaia, A K, Tsaturian
Publikováno v:
Biofizika. 40(3)
A new in vitro approach to study biological motility called movement or motility assay has been developed in last ten years. The method enabling direct observation of actin filament movement through the light microscope permits rather simple measurem
Autor:
A K, Tsaturian
Publikováno v:
Biofizika. 36(4)
A kinetic scheme of the mechano-chemical cycle of the cross-bridges and a mathematical model based on this scheme are proposed. The main assumptions accepted in the scheme are: the step of the inorganic phosphate release precedes the force-generating
Autor:
A K, Tsaturian, D M, Antipov
Publikováno v:
Biofizika. 36(4)
Using a recently proposed model of muscle contraction with a modified six-state kinetic scheme of the cross-bridge cycle, computer simulation was made of the dependence of the muscle fibre tension, stiffness and ATPase rate on the contraction velocit