Zobrazeno 1 - 10
of 84
pro vyhledávání: '"A K, Tanswell"'
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 288:L384-L389
We recently reported the existence of a bronchial epithelium-derived relaxing factor (BrEpRF) capable of reducing pulmonary arterial smooth muscle force generation in the newborn rat. We reasoned in this study that BrEpRF has physiological significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cbf7b692b0a575193d6b116941621b
https://doi.org/10.1152/ajplung.00309.2004
https://doi.org/10.1152/ajplung.00309.2004
Publikováno v:
Journal of Applied Physiology. 95:1979-1985
8-Isoprostaglandin F2α (8-iso-PGF2α) is a bioactive lipid peroxidation product that is a vasoconstrictor at high concentrations. Paradoxically, at lower, and possibly physiological, concentrations, it is a pulmonary vascular muscle's relaxant. Its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112b631120370c45ca5ab95ff31509fd
https://doi.org/10.1152/japplphysiol.00420.2003
https://doi.org/10.1152/japplphysiol.00420.2003
Publikováno v:
Journal of Applied Physiology. 94:2303-2312
Neonatal rats exposed to 60% O2 for 14 days develop lung changes compatible with human bronchopulmonary dysplasia and pulmonary hypertension. Our aim was to evaluate and compare the newborn and adult rat pulmonary vascular and airway smooth muscle fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9d31109f80c4cb41e67d4254051edc
https://doi.org/10.1152/japplphysiol.00820.2002
https://doi.org/10.1152/japplphysiol.00820.2002
Autor:
Judy Cabacungan, Xiaoping Luo, Stephen J. Lye, Helena Frndova, R. P. Jankov, Rosetta Belcastro, A. K. Tanswell
Publikováno v:
Pediatric Research. 48:289-298
We hypothesized that reactive O2 species, or their intermediary products, generated during exposure to elevated O2 lead to pathologic endothelin-1 expression in the newborn lung. Endothelin-1 expression and 8-isoprostane content (an in vivo marker of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f807db67afcea3a20aa004f2c51b97f8
https://doi.org/10.1203/00006450-200009000-00005
https://doi.org/10.1203/00006450-200009000-00005
Publikováno v:
Journal of Membrane Biology. 168:91-101
The aim of the present study was to investigate the roles of Ca2+ and protein tyrosine kinase (PTK) in the insulin action on cell volume in fetal rat (20-day gestational age) type II pneumocytes. Insulin (100 nm) increased cell volume in the presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12592d8b86af6b40b75920ec1019141e
https://doi.org/10.1007/s002329900500
https://doi.org/10.1007/s002329900500
Publikováno v:
Neonatology. 73:112-120
Lung epithelial and mesenchymal cells are separated by a basement membrane. At late fetal gestation, this basement membrane in fenestrated, allowing epithelial cytoplasmic extensions to reach in close proximity of the interstitial fibroblast. The enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ace6ac8385170046ea6e765e2286864
https://doi.org/10.1159/000013967
https://doi.org/10.1159/000013967
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 75:1030-1033
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe7e0f558ab334c45a5a67fde673cc0
https://doi.org/10.1139/y97-122
https://doi.org/10.1139/y97-122
Autor:
A. K. Tanswell, Hugh O'Brodovich
Publikováno v:
Current Opinion in Pediatrics. 9:141-145
There are currently a large number of ongoing gene therapy trials in North America and Europe. These trials have almost exclusively involved patients with inherited lethal disorders or malignancies. Although there are significant ethical and safety i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9c557e03f8bb5fe3ddce5d5129d37d
https://doi.org/10.1097/00008480-199704000-00004
https://doi.org/10.1097/00008480-199704000-00004
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 75:1030-1033
On a examine les effets d'un agoniste β 2 -adrenergique (agoniste β 2 ) et de l'AMPc sur la concentration de Ca 2+ cytosolique ([Ca 2+ ] c ) et sur le volume cellulaire dans les cellules de l'epithelium pulmonaire distal foetal. Tant la terbutaline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c5fcfdc5aa351653edf684ead530427
https://doi.org/10.1139/cjpp-75-8-1030
https://doi.org/10.1139/cjpp-75-8-1030
Publikováno v:
Development. 122:3107-3115
Lung branching morphogenesis depends on mesenchymalepithelial tissue interactions. Keratinocyte growth factor (KGF) has been implicated to be a regulator of these tissue interactions. In the present study, we investigated the role of KGF in early rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee0cd3d992c5fb5784e82a672fd609f
https://doi.org/10.1242/dev.122.10.3107
https://doi.org/10.1242/dev.122.10.3107