Zobrazeno 1 - 10
of 18
pro vyhledávání: '"A K, Ratty"'
Publikováno v:
Behavioral Neuroscience. 128:460-467
Schizophrenia is a prevalent neurodevelopmental psychiatric disorder with poor prognosis and limited understanding of its etiology. This limited etiological understanding renders developing animal models of schizophrenia difficult. Although attempts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f775e770e8e796e4dfda9f2c0f2e7f2c
https://doi.org/10.1037/a0036425
https://doi.org/10.1037/a0036425
Autor:
Gavin S. Dawe, Anil K. Ratty
Publikováno v:
Biotechnology Journal. 2:1344-1352
The chakragati (ckr) mouse is a serendipitously discovered insertional transgenic mutant that exhibits circling and hyperactivity. Studies of social behavior, sensorimotor gating and ventricular anatomy suggest that the ckr mouse models aspects of sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10372bb16906eeddcf9b0a28a22b9aa6
https://doi.org/10.1002/biot.200700145
https://doi.org/10.1002/biot.200700145
Publikováno v:
University of Bristol-PURE
The single-copy genes encoding the vasopressin and oxytocin prepropeptides are closely linked in mouse genome, being separated by an intergenic region of only 3 kbp. These genes are expressed in anatomically defined hypothalamic neurons—in the adul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20fc8c814248c8112be551f64db62e0
https://doi.org/10.1016/s0168-0102(98)00017-0
https://doi.org/10.1016/s0168-0102(98)00017-0
Publikováno v:
Cellular and Molecular Neurobiology. 18:149-171
1. Studies of the regulation of neurosecretory cell gene expression suffer from the lack of suitable cell lines. Two approaches have been used to overcome this deficit: transfection of neuropeptide genes into heterologous cell lines and generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33dbbc8a71329fa31aa5fb9da9145a71
https://doi.org/10.1023/a:1022512819023
https://doi.org/10.1023/a:1022512819023
Autor:
Dominic J. Smiraglia, Chuanzhen Wu, Mary K. Ellsworth, Anil K. Ratty, Verne M. Chapman, Kenneth W. Gross
Publikováno v:
Genomics. 45:572-579
We have previously reported that the circling phenotype of the chakragati mouse segregates with the transgene integration event as an autosomal recessive trait. It was unclear, however, whether the phenotype was linked to the transgene integration po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f7226b90fd3e14ac23c47184ff14c2
https://doi.org/10.1006/geno.1997.4976
https://doi.org/10.1006/geno.1997.4976
Autor:
Hemin Chin, Anil K. Ratty, Harold Gainer, David Murphy, James W. Nagle, Byrappa Venkatesh, Seong-Whan Jeong
Publikováno v:
Gene. 174:71-78
The genomic region between the oxytocin (OT) and vasopressin (VP) genes in the two strains of mice was independently sequenced by our two groups. In this report, we present our collated sequence data and analyses. The mouse intergenic region (MUIGR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6545fa8a6101bc8dab578e7634d3762
https://doi.org/10.1016/0378-1119(96)00370-8
https://doi.org/10.1016/0378-1119(96)00370-8
Publikováno v:
Mammalian Genome. 3:5-10
We present here the genetic mapping of two novel loci, D16Ros1 and D16Ros2, to mouse Chromosome (Chr) 16. The probes for these loci were genomic fragments isolated from the chakragati mouse, a behavioral mutant resulting from insertional mutagenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c25064151b3c6266f1eeac9aeb5424
https://doi.org/10.1007/bf00355834
https://doi.org/10.1007/bf00355834
Autor:
Lawrence W. Fitzgerald, Anil K. Ratty, Keith J. Miller, Mary K. Ellsworth, Stanley D. Glick, Kenneth W. Gross
Publikováno v:
Behavioral Neuroscience. 105:755-763
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91d97584f4c94422110d1b8643a91e73
https://doi.org/10.1037/0735-7044.105.5.755
https://doi.org/10.1037/0735-7044.105.5.755
The chakragati mouse shows deficits in prepulse inhibition of acoustic startle and latent inhibition
Autor:
Richard Salvi, Craig A. Jones, Vivek Verma, Kenneth W. Gross, G. A. Grigor'yan, Wei-Yi Ong, Gavin S. Dawe, Anil K. Ratty, Daniel Stolzberg, Chay Hoon Tan
Publikováno v:
Neuroscience research. 60(3)
The chakragati (ckr) mouse, which was serendipitously created as a result of a transgenic insertional mutation, has been proposed as a model of aspects of schizophrenia. The mice exhibit circling, hyperactivity, reduced social interactions, and enlar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86df754f13d89070dc591e9779d08b02
https://pubmed.ncbi.nlm.nih.gov/18164085
https://pubmed.ncbi.nlm.nih.gov/18164085
Publikováno v:
Genomics. 45(3)
The circling phenotype of the chakragati mouse is a result of a transgenic insertional mutation. The absence of the phenotype in mice heterozygous for the transgene insertion suggests that this is due to a loss of function of an endogenous gene. Effo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a28cc2045a62d3dd26345114f844ca
https://pubmed.ncbi.nlm.nih.gov/9367681
https://pubmed.ncbi.nlm.nih.gov/9367681