Zobrazeno 1 - 10
of 115
pro vyhledávání: '"A K, Foulis"'
Autor:
Donald C. McMillan, Campbell S.D. Roxburgh, H.C. van Wyk, Paul G. Horgan, Alan K. Foulis, James H. Park
Publikováno v:
Cancer Treatment Reviews. 41:151-159
Tumour budding reflects a detachment of tumour cells at the invasive front of carcinomas and is presumed to be an early step in the metastatic process. Tumour budding has received some attention in colorectal cancer as it has been proposed as an addi
Publikováno v:
IUBMB Life. 66:723-734
Type 1 diabetes mellitus (T1DM) is caused by the selective deletion of pancreatic β-cells in response to an assault mounted within the pancreas by infiltrating immune cells. However, this apparently clear and focussed annunciation conceals a stark r
Autor:
Deborah Kronenberg-Versteeg, Sarah J. Richardson, Abby Willcox, Katherine Marks, John A. Todd, Noel G. Morgan, Nurhanani Mohamed Nor, Jake Powrie, Polly J. Bingley, Megan Estorninho, Alan K. Foulis, Pia Leete, David B. Dunger, Catherine Guy, Anna Lorenc, Sefina Arif, Mark Peakman, Vy Nguyen, Emanuele de Rinaldis
Publikováno v:
Diabetes
Studies in type 1 diabetes indicate potential disease heterogeneity, notably in the rate of β-cell loss, responsiveness to immunotherapies, and, in limited studies, islet pathology. We sought evidence for different immunological phenotypes using two
Autor:
Alan K. Foulis, Campbell S.D. Roxburgh, Colin H. Richards, Paul G. Horgan, Donald C. McMillan, Arfon Powell
Publikováno v:
European Journal of Cancer. 50:309-319
Background The host immune response is important in the prevention of tumour progression in solid organ cancers. The aim was to evaluate the clinical utility of the local inflammatory response in patients with colorectal cancer. Methods Three hundred
Autor:
Pia Leete, Alan K. Foulis, Maarit Oikarinen, Therese Rosenling, Sarah J. Richardson, Adrian J. Bone, Shalinee Dhayal, Katharina Lind, Mark Russell, Gun Frisk, Noel G. Morgan, Malin Flodström-Tullberg, Jutta E. Laiho, Heikki Hyöty, Didier Hober, Emma Svedin, Nora M. Chapman
Publikováno v:
Diabetologia; Vol 57
Enteroviral infection has been implicated in the development of islet autoimmunity in type 1 diabetes and enteroviral antigen expression has been detected by immunohistochemistry in the pancreatic beta cells of patients with recent-onset type 1 diabe
Autor:
Colin J. McKay, C. Ross Carter, Alan K. Foulis, Nigel B. Jamieson, Nigel I. J. Chan, Euan J. Dickson
Publikováno v:
Journal of Gastrointestinal Surgery. 17:511-521
The poor overall survival associated with pancreatic ductal adenocarcinoma (PDAC) despite complete resection suggests that occult metastatic disease is present in most at the time of surgery. Resection margin involvement (R1) following resection is a
Publikováno v:
Diabetologia; Vol 56
Immunohistochemical staining reveals that the enteroviral capsid protein VP1 is present at higher frequency in the insulin-containing islets of patients with recent-onset type 1 diabetes than in controls. This is consistent with epidemiological evide
Autor:
Clem W. Imrie, Alan K. Foulis, Nigel B. Jamieson, Euan J. Dickson, Colin J. McKay, Donald C. McMillan, Karin A. Oien, C. Ross Carter, Mohamed A. Mohamed
Publikováno v:
Annals of Surgical Oncology. 19:3581-3590
The tumor-associated inflammatory cell infiltrate is recognized to have prognostic value in various common solid tumors. However, the prognostic value of the tumor inflammatory cell infiltrate has not been established in pancreatic ductal adenocarcin
Autor:
Paul G. Horgan, Donald C. McMillan, Colin H. Richards, Susan Moug, Alan K. Foulis, Campbell S.D. Roxburgh
Publikováno v:
International Journal of Colorectal Disease. 27:363-369
The optimal surgical strategy for patients presenting with colorectal liver metastases has yet to be determined. Short- and long-term outcomes must be considered if simultaneous resection of primary and liver metastases is to gain acceptance. We exam
Autor:
James H. Anderson, Ruth F. McKee, Donald C. McMillan, Campbell S.D. Roxburgh, Alan K. Foulis, Paul G. Horgan, Colin H. Richards
Publikováno v:
British Journal of Surgery. 99:287-294
Background Tumour necrosis is a marker of poor prognosis in some tumours but the mechanism is unclear. This study examined the prognostic value of tumour necrosis and host inflammatory responses in colorectal cancer. Methods This was a retrospective