Zobrazeno 1 - 10
of 202
pro vyhledávání: '"A Joseph, Tector"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Seventy to ninety percentage of preformed xenoreactive antibodies in human serum bind to the galactose-α(1,3)-galactose Gal epitope, and the creation of Gal knockout (KO) pigs has eliminated hyperacute rejection as a barrier to xenotransplantation.
Externí odkaz:
https://doaj.org/article/b82e0f16d92b49ffa0e3a9d83e6cafde
Autor:
Takayuki Yamamoto, Qi Li, Hidetaka Hara, Liaoran Wang, Hongmin Zhou, Juan Li, Devin E. Eckhoff, A. Joseph Tector, Edwin C. Klein, Ray Lovingood, Mohamed Ezzelarab, David Ayares, Yi Wang, David K.C. Cooper, Hayato Iwase
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 1965-1974 (2018)
This report is related to the research article entitled “B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy” (Yamamoto et al., in press). Herein we provide the data regarding pig artery patc
Externí odkaz:
https://doaj.org/article/9d0de587a0d34f36a487a19b6e26b0ae
Autor:
Hongmin Zhou, Zhongqiang Zhang, A. Joseph Tector, Qi Li, Juan Li, Hayato Iwase, David Ayares, Hendrik Jan Schuurman, Takayuki Yamamoto, Jeremy B. Foote, Liaoran Wang, Devin E. Eckhoff, Edwin Klein, David K. C. Cooper, Hidetaka Hara, Ray Lovingood, Mohamed Ezzelarab
Publikováno v:
Transplantation. 103:2090-2104
The aims of this study were to evaluate the efficacy of US Food and Drug Administration-approved drugs in genetically engineered pig-to-baboon kidney xenotransplantation and compare the results with those using an anti-CD40 monoclonal antibody (mAb)-
Autor:
Elizabeth Strobert, Laura B. Higginbotham, Alfred Joseph Tector, Joseph M. Ladowski, Andrew B. Adams, Eric M. Walters, David V. Mathews, Alton B. Farris, Joe B. Jenkins, Gregory Martens, Cynthia P. Breeden, Christian P. Larsen, Allison Stephenson, Matthew Tector, Steven C. Kim
Publikováno v:
Am J Transplant
The shortage of available organs remains the greatest barrier to expanding access to transplantation. Despite advances in genetic editing and immunosuppression, survival in experimental models of kidney xenotransplantation has generally been limited
Autor:
Zheng-Yu Wang, James R. Butler, Devin E. Eckhoff, Joseph M. Ladowski, Clarkson Smith, Luz M. Reyes, Joseph Tector, Juliet L. Easlick, Jose Estrada, Gregory R. Martens, Matthew Tector, Richard A. Sidner
Publikováno v:
Transplantation. 103:1620-1629
Background Highly sensitized patients are difficult to match with suitable renal allograft donors and may benefit from xenotransplant trials. We evaluate antibody binding from sensitized patients to pig cells and engineered single allele cells to ide
Autor:
Phillipe Abreu, Vighnesh Venkatasamy, Juliano Riella, Giselle Guerra, Rafael Miyashiro, Alfred Joseph Tector, Akin Tekin, Gennaro Selvaggi, Rodrigo Vianna
Publikováno v:
Transplantation. 106:S354-S354
Publikováno v:
Xenotransplantation. 27
Progress has been made in overcoming antibody-mediated rejection of porcine xenografts by deleting pig genes that produce unique carbohydrate epitopes. Pigs deficient in galactose α-1,3 galactose (gene modified: GGTA1) and neu5Gc (gene modified: CMA
Autor:
Andrew B. Adams, Alton B. Farris, Brendon Lovasik, Stuart J. Knechtle, A. Joseph Tector, Jean Kwun
Publikováno v:
Clinical Xenotransplantation ISBN: 9783030491260
Antibody-mediated rejection (AMR) is a barrier to successful long-term xenograft survival. We compared AMR in kidney xenotransplantation to sensitized kidney allotransplantation in a nonhuman primate model. With conventional CNI-based immunosuppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15466347df15f09a8b44fe2a8abeb0be
https://doi.org/10.1007/978-3-030-49127-7_9
https://doi.org/10.1007/978-3-030-49127-7_9
Autor:
Liaoran Wang, Juan Li, Mohamed Ezzelarab, Hongmin Zhou, Hayato Iwase, Hidetaka Hara, Yi Wang, David K. C. Cooper, David Ayares, Takayuki Yamamoto, Edwin Klein, Ray Lovingood, A. Joseph Tector, Qi Li, Devin E. Eckhoff
Publikováno v:
Data in Brief, Vol 20, Iss, Pp 1965-1974 (2018)
Data in Brief
Data in Brief
This report is related to the research article entitled "B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy" (Yamamoto et al., in press). Herein we provide the data regarding pig artery patch xe
Autor:
Luz M. Reyes, Rafael Miyashiro Nunes dos Santos, Luiz Augusto Carneiro D'Albuquerque, Matthew Tector, A. Joseph Tector, Zheng-Yu Wang, Jose Estrada
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background Tools for genome editing in pigs are improving rapidly so that making precise cuts in DNA for the purposes of deleting genes is straightforward. Development of means to replace pig genes with human genes with precision is very desirable fo