Zobrazeno 1 - 10
of 65
pro vyhledávání: '"A J W Sim"'
Publikováno v:
eLife, Vol 11 (2022)
Dimorphic amino acids at positions 77 and 80 delineate HLA-C allotypes into two groups, C1 and C2, which associate with disease through interactions with C1 and C2-specific natural killer cell receptors. How the C1/C2 dimorphism affects T cell recogn
Externí odkaz:
https://doaj.org/article/5841704976004318b63b6c5d29ac4331
Autor:
Malcolm J. W. Sim, Peter D. Sun
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In cancer, non-synonymous DNA base changes alter protein sequence and produce neoantigens that are detected by the immune system. For immune detection, neoantigens must first be presented on class I or II human leukocyte antigens (HLA) followed by re
Externí odkaz:
https://doaj.org/article/bfb13742b2ad4c60862c0d6e150c8588
Autor:
Malcolm J. W. Sim, Paul Brennan, Katherine L. Wahl, Jinghua Lu, Sumati Rajagopalan, Peter D. Sun, Eric O. Long
SummaryGenetic studies associate killer-cell immunoglobulin-like receptors (KIR) and their HLA class I ligands with a variety of human diseases. The basis for these associations, and the relative contribution of inhibitory and activating KIR to NK ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d827f88cf384cacca04290523917c8c6
https://doi.org/10.1101/2023.02.06.527249
https://doi.org/10.1101/2023.02.06.527249
Publikováno v:
eLife. 11
Dimorphic residues at positions 77 and 80 delineate HLA-C allotypes into two groups, C1 and C2, which associate with disease through interactions with C1 and C2-specific natural killer cell receptors. How the C1/C2 dimorphism affects T cell recogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7339927e2d00e0b3a3f0097d9215c58b
https://doi.org/10.7554/elife.75670
https://doi.org/10.7554/elife.75670
Autor:
Steven A. Rosenberg, Peter D. Sun, Eric O. Long, Matthew Spencer, Jinghua Lu, Malcolm J. W. Sim, Eric Tran, Francis Hopkins
Publikováno v:
Proc Natl Acad Sci U S A
Complete cancer regression occurs in a subset of patients following adoptive T cell therapy (ACT) of ex vivo expanded tumor-infiltrating lymphocytes (TILs). However, the low success rate presents a great challenge to broader clinical application. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc41b873d72859dc2c0078506d899c8f
https://pubmed.ncbi.nlm.nih.gov/33077608
https://pubmed.ncbi.nlm.nih.gov/33077608
Autor:
Malcolm J W, Sim, Sumati, Rajagopalan, Daniel M, Altmann, Rosemary J, Boyton, Peter D, Sun, Eric O, Long
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(26)
Natural killer (NK) cells have an important role in immune defense against viruses and cancer. Activation of human NK cell cytotoxicity toward infected or tumor cells is regulated by killer cell immunoglobulin-like receptors (KIRs) that bind to human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3001cbc2ac4e87652a8b20262466f99c
https://pubmed.ncbi.nlm.nih.gov/31175150
https://pubmed.ncbi.nlm.nih.gov/31175150
Autor:
T Browne, N Miller, S Moore, R Pierce, A Holzapfel, J. W. Sim, R Maloney, J Watts, E Neill, R Keedwell
Publikováno v:
New Zealand Journal of Zoology. 43:258-274
Pāteke, brown teal (Anas chlorotis) were until recently restricted to two key strongholds in northern New Zealand: Great Barrier Island and eastern Northland. In 2000, we applied predator control at two sites within the strongholds. We analysed thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88559483dafd47b83bc20cb0fdc95aff
https://doi.org/10.1080/03014223.2016.1154078
https://doi.org/10.1080/03014223.2016.1154078
Autor:
Malcolm J. W. Sim, Peter D. Sun
Publikováno v:
Immunity. 46:972-974
HLA-F, a non-classical MHC molecule, is not known to present peptides. Dulberger et al. (2017) show that HLA-F contains a distinct peptide-binding groove and can present a diverse array of peptides. LIR1, however, recognized HLA-F away from bound pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0674be58eb2f44cd309772a0d7244ab6
https://doi.org/10.1016/j.immuni.2017.06.004
https://doi.org/10.1016/j.immuni.2017.06.004
Publikováno v:
Journal of Geotechnical and Geoenvironmental Engineering. 144
This paper reports a measure for easing spudcan-footprint interactions when a jack-up rig needs to be installed near existing jack-up footprints. Two novel spudcan shapes, a skirted spudcan...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6c7f27f6007465678b0ce945657e29
https://doi.org/10.1061/(asce)gt.1943-5606.0001925
https://doi.org/10.1061/(asce)gt.1943-5606.0001925