Co-inhibitor expression on tumor infiltrating and splenic lymphocytes after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer

Autor: Ryan J. Slovak, Hong-Jai Park, William M. Kamp, Johannes M. Ludwig, Insoo Kang, Hyun S. Kim

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)

Abstract Checkpoint inhibitors have demonstrated clinical impact in colorectal cancer with deficient mismatch repair and high microsatellite instability. However, the majority of patients have disease with stable microsatellites that responds poorly

Externí odkaz: https://doaj.org/article/c3f1eaec71aa4d68a08a5f210792e245

Multicenter, dose-ranging study of efegatran sulfate versus heparin with thrombolysis for acute myocardial infarction: The Promotion of Reperfusion in Myocardial Infarction Evolution (PRIME) trial

Autor: T. Fawcett, P. DeSantis, David R. Jacobs, J. Kmonicek, A. Stein, T. Browning, Jean-Francois Marquis, A. Friedewald, J. Glassman, William J. French, L. Cahoon, A. Edwards, Douglas Spriggs, Jeffery J. Johnson, J. Slovak, A. N. Tenaglia, J. Scrivner, K. Browne, M. Telatnik, J. Calarco, V. Foulger, K. Teeter, M. Bloom, K. Knepper, D. Goodman, B. Owens, D. L. Brewer, Neal S. Kleiman, Erik Magnus Ohman, Seth J. Worley, B. Kennelly, J. Butler, M. Hudson, M. Boyles, J. S. Wilson, Joanne White, C. Clinton, K. Carr, James B. Hermiller, D. Marsh, M. Bulley, B. Penny, S. Diel, J. Bengtson, M. Myrna, L. Baysinger, M. J. Koren, L. Hollywood, J. Shane, Gérald Barbeau, S. Wahl, S. Webber, M. J. Miller, David J. Moliterno, R. Bozeman, F. M. Krainin, M. Adolphson, C. Corder, C Kells, J. D. Talley, R. Andersen, K. Fletcher, A. G. Adelman, W. Grossman, D. Walston, M. M. Lariviere, Shaojun Wang, J. L. Gard, C. Martz, K. Porter, David L. Brown, D. Small, Martin J. Frey, Sharon Ann Kearns, D. Almond, W. Roper

Publikováno v: American Heart Journal. 143:95-105

Background Adjunctive therapies that increase the incidence of normal reperfusion after thrombolysis for acute myocardial infarction (MI) could enhance clinical outcomes. Direct thrombin inhibitors may offer an advantage over standard adjunctive ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de890b0b4279a29ac5c30d258f142c6
https://doi.org/10.1067/mhj.2002.119896

Trap for polarized atoms based on light-induced drift

Autor: Hradecn C, Buric F, T. Tethal, I.M. Yermolayev, J. Slovak

Publikováno v: Physical Review A. 54:3250-3253

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec9a4484e76014c242cdb8709965978
https://doi.org/10.1103/physreva.54.3250

Radioactive isotope and isomer separation using the light induced drift effect

Autor: T. Tethal, C. Hradecny, A.M. Shalagin, I.M. Yermolayev, J. Slovak

Publikováno v: International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes. 43:1259-1264

Isotope separation with using light induced drift (LID) is discussed. Two basic theoretical characteristics of the method are deduced. I, separation simultaneously with an arbitrary high enrichment and without significant losses; 2, high separation p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ea8672c1c45cc8ad926a606e1a5b644
https://doi.org/10.1016/0883-2889(92)90204-r

Low temperature nuclear orientation of238NpGd

Autor: Michael Finger Jr, V. N. Pavlov, J. Slovak, I. Novotný, Jan John, E. Šimečková

Publikováno v: Hyperfine Interactions. 59:181-184

The decay of238Np oriented at low temperatures in gadolinium host was investigated. Multipole mixing ratios for beta-transition to the level 1028.6 keV and nine gamma-transitions in238Pu were calculated from the anisotropies of gamma radiation. The a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dabdb45129ec7097d96bd4ecd5043a4d
https://doi.org/10.1007/bf02401219