Zobrazeno 1 - 10
of 201
pro vyhledávání: '"A J Simpkin"'
Autor:
Filomeno Sánchez Rodríguez, Adam J. Simpkin, Grzegorz Chojnowski, Ronan M. Keegan, Daniel J. Rigden
Publikováno v:
IUCrJ, Vol 11, Iss 6, Pp 938-950 (2024)
The accuracy of the information in the Protein Data Bank (PDB) is of great importance for the myriad downstream applications that make use of protein structural information. Despite best efforts, the occasional introduction of errors is inevitable, e
Externí odkaz:
https://doaj.org/article/5e6b06cec2dd4c3b99bbba3590a1c3f6
Autor:
Tanya Talkar, Daniel M. Low, Andrew J. Simpkin, Satrajit Ghosh, Derek T. O’Keeffe, Thomas F. Quatieri
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract In the face of the global pandemic caused by the disease COVID-19, researchers have increasingly turned to simple measures to detect and monitor the presence of the disease in individuals at home. We sought to determine if measures of neurom
Externí odkaz:
https://doaj.org/article/1c2896c08e0c4b5c8b026c18668d822a
Autor:
Bairbre A. McNicholas, Emanuele Rezoagli, Andrew J. Simpkin, Sankalp Khanna, Jacky Y. Suen, Pauline Yeung, Daniel Brodie, Gianluigi Li Bassi, Tai Pham, Giacomo Bellani, John F. Fraser, John Laffey, on behalf of the CCCC Consortium
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-14 (2023)
Abstract Background Acute kidney injury (AKI) is a frequent and severe complication of both COVID-19-related acute respiratory distress syndrome (ARDS) and non-COVID-19-related ARDS. The COVID-19 Critical Care Consortium (CCCC) has generated a global
Externí odkaz:
https://doaj.org/article/60e1e677b09f4f698adf996f8977182e
Autor:
Sarah Holmes Watkins, Karen Ho, Christian Testa, Louise Falk, Patrice Soule, Linda V. Nguyen, Sophie FitzGibbon, Catherine Slack, Jarvis T. Chen, George Davey Smith, Immaculata De Vivo, Andrew J. Simpkin, Kate Tilling, Pamela D. Waterman, Nancy Krieger, Matthew Suderman, Caroline Relton
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2366-2376 (2022)
DNA methylation (DNAm) is commonly assayed using the Illumina Infinium MethylationEPIC BeadChip, but there is currently little published evidence to define the lower limits of the amount of DNA that can be used whilst preserving data quality. Such ev
Externí odkaz:
https://doaj.org/article/eb96d333ade340c9b3ea5ba8f715f287
Autor:
Alexandre A. Lussier, Yiwen Zhu, Brooke J. Smith, Andrew J. Simpkin, Andrew D.A.C. Smith, Matthew J. Suderman, Esther Walton, Kerry J. Ressler, Erin C. Dunn
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1373-1388 (2022)
Biomedical research has grown increasingly cooperative through the sharing of consortia-level epigenetic data. Since consortia preprocess data prior to distribution, new processing pipelines can lead to different versions of the same dataset. Similar
Externí odkaz:
https://doaj.org/article/daf87760dcf940bba874e8977ca8eee4
Autor:
Grzegorz Chojnowski, Adam J. Simpkin, Diego A. Leonardo, Wolfram Seifert-Davila, Dan E. Vivas-Ruiz, Ronan M. Keegan, Daniel J. Rigden
Publikováno v:
IUCrJ, Vol 9, Iss 1, Pp 86-97 (2022)
Although experimental protein-structure determination usually targets known proteins, chains of unknown sequence are often encountered. They can be purified from natural sources, appear as an unexpected fragment of a well characterized protein or app
Externí odkaz:
https://doaj.org/article/c1c2d178143c4afebef407a453f3cfb8
Autor:
Marie Le Berre, Terézia Paulovčáková, Carolina De Marco Verissimo, Seán Doyle, John P Dalton, Claire Masterson, Eduardo Ribes Martínez, Laura Walsh, Conor Gormley, John G Laffey, Bairbre McNicholas, Andrew J Simpkin, Michelle Kilcoyne
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283537 (2023)
Zoonotic spillover of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans in December 2019 caused the coronavirus disease 2019 (COVID-19) pandemic. Serological monitoring is critical for detailed understanding of individual immune
Externí odkaz:
https://doaj.org/article/f8c17fe0125b43b9a646d144d9f63507
Autor:
Beatrice Charamba, Aaron Liew, Asma Nadeem, John Newell, Derek T O'Keeffe, Timothy O'Brien, William Wijns, Atif Shahzad, Andrew J Simpkin
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0269968 (2023)
ObjectivesThere has been a steady increase in the number of studies of the complex relationship between glucose and electrical cardiac activity which use simultaneous continuous glucose monitors (CGM) and continuous electrocardiogram (ECG). However,
Externí odkaz:
https://doaj.org/article/52ce52178171488e9fd9a9c0230004f4
Autor:
Bairbre A. McNicholas, Emanuele Rezoagli, Andrew J. Simpkin, Sankalp Khanna, Jacky Y. Suen, Pauline Yeung, Daniel Brodie, Gianluigi Li Bassi, Tai Pham, Giacomo Bellani, John F. Fraser, John Laffey, the CCCC Consortium
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/262c9a0debc3447286e799fb77baa919
Autor:
Talha Iqbal, Pau Redon-Lurbe, Andrew J. Simpkin, Adnan Elahi, Sandra Ganly, William Wijns, Atif Shahzad
Publikováno v:
IEEE Access, Vol 9, Pp 93567-93579 (2021)
Stress is known as a silent killer that contributes to several life-threatening health conditions such as high blood pressure, heart disease, and diabetes. The current standard for stress evaluation is based on self-reported questionnaires and standa
Externí odkaz:
https://doaj.org/article/a7e827adcc584134babcea5ae08b4903