Zobrazeno 1 - 10
of 16
pro vyhledávání: '"A J Schlabach"'
The Partnership for Chemicals Risk Assessment (PARC) is currently under development as a joint research and innovation programme to strengthen the scientific basis for chemical risk assessment in the EU. The plan is to bring chemical risk assessors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::9ef8f41da98042a07cd845eea4c944f0
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3057544
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3057544
Non-target screening (NTS) including suspect screening with high resolution mass spectrometry has already shown its feasibility in detecting and identifying emerging contaminants, which subsequently triggered exposure mitigating measures. NTS has a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::f270a195e859ef79e795168e52d7d0cf
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3057670
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3057670
Autor:
W J Long, J A Wolfgang, Jon H. Condra, V V Sardana, A J Schlabach, C L Schneider, J A Waterbury, B S Wolanski, William A. Schleif, V W Byrnes
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:1576-1579
The nonnucleoside reverse transcriptase (RT) inhibitors comprise a class of structurally diverse compounds that are functionally related and specific for the human immunodeficiency virus type 1 RT. Viral variants resistant to these compounds arise re
Autor:
Jill A. Wolfgang, V V Sardana, William J. Long, Donald J. Graham, Emilio A. Emini, Donald W. Lineberger, Jon H. Condra, A J Schlabach, Leah Gotlib
Publikováno v:
Journal of Biological Chemistry. 267:17526-17530
Several novel, structurally distinct classes of specific human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) nonnucleoside inhibitors have been described recently. These include the pyridinone derivatives L-697,639, L-697,661, and
Autor:
J A Wolfgang, R J Colonno, V V Sardana, A J Schlabach, Jon H. Condra, L Gotlib, Emilio A. Emini, Donald J. Graham
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:1441-1446
The reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) is potently inhibited by a structurally diverse group of nonnucleoside compounds. These include pyridinone derivatives, tetrahydroimadazo[4,5,1-j,k][1,4]-benzodiazepin-2(1H
Autor:
Richard J. Colonno, Joanne E. Tomassini, Leah Gotlib, V V Sardana, M E Davies, Donald W. Lineberger, Jon H. Condra, Donald J. Graham, A J Schlabach
Publikováno v:
Journal of Biological Chemistry. 265:2292-2295
Human rhinoviruses are the major causative agents of the common cold in humans and have been divided into major and minor groups based on receptor specificity. cDNAs encoding the light and heavy chains of a murine monoclonal antibody that recognizes
Publikováno v:
ECBS
Stability and support operations (SASO) are becoming increasingly important in modern military operations. Conflicts are no longer comprised solely of two opposing sides engaged in combat on an open battlefield. Instead, they are more likely to invol
Publikováno v:
SMC
The current state of military operations includes many stability and support (SASO), multi-sided conflicts. The research presented in this paper attempts to address this complex environment by creating a SASO simulation, coevolutionary generation of
Autor:
Donald J. Graham, J A Wolfgang, W J Long, Emilio A. Emini, L Gotlib, William A. Schleif, Jon H. Condra, C L Schneider, V W Byrnes, A J Schlabach
Publikováno v:
Antimicrobial agents and chemotherapy. 38(6)
To evaluate the potential that multiply resistant human immunodeficiency virus type 1 variants may arise during combination nucleoside and nonnucleoside reverse transcriptase inhibitor therapy, we constructed a series of mutant reverse transcriptase
Autor:
Culberson Jc, R L LaFemina, Kohl Ne, Donald J. Graham, Graham P, V V Sardana, Gotlib L, Jon H. Condra, A J Schlabach, Bush Bl
Publikováno v:
Biochemistry. 33(8)
The human immunodeficiency virus type 1 (HIV-1) protease is a homodimeric aspartyl endopeptidase that is required for virus replication. A number of specific, active-site inhibitors for this enzyme have been described. Many of the inhibitors exhibit