Zobrazeno 1 - 10
of 275
pro vyhledávání: '"A J Sant"'
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109992- (2024)
Summary: The studies reported here focus on the impact of pre-existing CD4 T cell immunity on the first encounter with SARS-CoV-2. They leverage PBMC samples from plasma donors collected after a first SARS-CoV-2 infection, prior to vaccine availabili
Externí odkaz:
https://doaj.org/article/a9bbb7698104469788e566c4ff8e1423
Autor:
Sean A. Nelson, Katherine A. Richards, Maryah A. Glover, Francisco A. Chaves, Michelle C. Crank, Barney S. Graham, Masaru Kanekiyo, Andrea J. Sant
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Nanoparticle vaccines based on H. pylori ferritin are increasingly used as a vaccine platform for many pathogens, including RSV, influenza, and SARS-CoV-2. They have been found to elicit enhanced, long-lived B cell responses. The basis for i
Externí odkaz:
https://doaj.org/article/fdb8daa72b4e4c18aca6e6142b4badea
Autor:
Chantelle L. White, Maryah A. Glover, Siva K. Gandhapudi, Katherine A. Richards, Andrea J. Sant
Publikováno v:
Vaccines, Vol 12, Iss 3, p 281 (2024)
It is clear that new approaches are needed to promote broadly protective immunity to viral pathogens, particularly those that are prone to mutation and escape from antibody-mediated immunity. CD4+ T cells, known to target many viral proteins and high
Externí odkaz:
https://doaj.org/article/77efefa51104490eb1720966d5705462
Autor:
Lauren R Parola, Megan P Pinette, Benedikt L Proffen, Nicholas J Sant, N Padmini Karamchedu, Meggin Q Costa, Janine Molino, Braden C Fleming, Martha M Murray
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0278338 (2022)
The study objective was to determine if intraarticular injections of an extracellular matrix (ECM) powder and blood composite (ECM-B) would have a significant impact on post-operative gait parameters without eliciting adverse cartilage changes or sev
Externí odkaz:
https://doaj.org/article/105a4be668024f419b01f1b36270ccd5
Autor:
Thomas R. Henson, Katherine A. Richards, Siva K. Gandhapudi, Jerold G. Woodward, Andrea J. Sant
Publikováno v:
Viruses, Vol 15, Iss 2, p 538 (2023)
It is clear that new approaches are needed to promote broadly protective immunity to viral pathogens, particularly those that are prone to mutation and escape from antibody-mediated immunity. Prototypic pathogens of this type are influenza and SARS-C
Externí odkaz:
https://doaj.org/article/9349ee20a25f415a9021e013f3fd4160
Autor:
Sean A. Nelson, Andrea J. Sant
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Yearly administration of influenza vaccines is our best available tool for controlling influenza virus spread. However, both practical and immunological factors sometimes result in sub-optimal vaccine efficacy. The call for improved, or even universa
Externí odkaz:
https://doaj.org/article/437b6f166f094ee5a8a528962e3faf91
Autor:
Jennifer Cable, Siddharth Balachandran, Lisa P. Daley‐Bauer, Arjun Rustagi, Ferrin Antony, Justin J. Frere, Jamie Strampe, Katherine Kedzierska, Judy L. Cannon, Maureen A. McGargill, Daniela Weiskopf, Robert C. Mettelman, Julia Niessl, Paul G. Thomas, Bryan Briney, Sophie A. Valkenburg, Jesse D. Bloom, Pamela J. Bjorkman, Sho Iketani, C. Garrett Rappazzo, Chelsea M. Crooks, Kali F. Crofts, Stefan Pöhlmann, Florian Krammer, Andrea J. Sant, Gary J. Nabel, Stacey Schultz‐Cherry
Publikováno v:
Annals of the New York Academy of Sciences. 1521:32-45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ae512b46e8bbda4f04547ea661655b
https://doi.org/10.1111/nyas.14960
https://doi.org/10.1111/nyas.14960
Autor:
Ajitanuj Rattan, Chantelle L. White, Sean Nelson, Max Eismann, Herbey Padilla-Quirarte, Maryah A. Glover, Thamotharampillai Dileepan, Bindumadhav M. Marathe, Elena A. Govorkova, Richard J. Webby, Katherine A. Richards, Andrea J. Sant
Publikováno v:
Pathogens, Vol 11, Iss 2, p 251 (2022)
The adaptive T cell response to influenza B virus is understudied, relative to influenza A virus, for which there has been considerable attention and progress for many decades. Here, we have developed and utilized the C57BL/6 mouse model of intranasa
Externí odkaz:
https://doaj.org/article/012e78623e6545a8bb6cc225113d664b
Autor:
Thomas E. Lachmar, Thomas G. Freeman, Christopher J. Sant, Jeffrey R. Walker, Joseph F. Batir, John W. Shervais, James P. Evans, Dennis L. Nielson, David D. Blackwell
Publikováno v:
Geothermal Energy, Vol 5, Iss 1, Pp 1-16 (2017)
Abstract A 1912-m exploration corehole was drilled along the axis of the eastern Snake River Plain, Idaho. Two temperature logs run on the corehole display an obvious inflection point at about 960 m. Such behavior is indicative of downward fluid flow
Externí odkaz:
https://doaj.org/article/a74bc7ac9fb04efc8f45371f48482bb4
Autor:
Sean A. Nelson, Andrea J. Sant
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Immunity to influenza is unique among pathogens, in that immune memory is established both via intermittent lung localized infections with highly variable influenza virus strains and by intramuscular vaccinations with inactivated protein-based vaccin
Externí odkaz:
https://doaj.org/article/ffb994293b434a50b600508744c00f9f