Zobrazeno 1 - 10
of 445
pro vyhledávání: '"A J Robison"'
Autor:
Elizabeth Martin, Asadur Chowdury, John Kopchick, Patricia Thomas, Dalal Khatib, Usha Rajan, Caroline Zajac-Benitez, Luay Haddad, Alireza Amirsadri, Alfred J. Robison, Katherine N. Thakkar, Jeffrey A. Stanley, Vaibhav A. Diwadkar
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionSchizophrenia is characterized by a loss of network features between cognition and reward sub-circuits (notably involving the mesolimbic system), and this loss may explain deficits in learning and cognition. Learning in schizophrenia has
Externí odkaz:
https://doaj.org/article/6af58a1492f443ef80462fc8f425b07c
Autor:
Jason R Klug, Brian N Mathur, Thomas L Kash, Hui-Dong Wang, Robert T Matthews, A J Robison, Mark E Anderson, Ariel Y Deutch, David M Lovinger, Roger J Colbran, Danny G Winder
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45323 (2012)
Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is abundant in striatal medium spiny neurons (MSNs). CaMKII is dynamically regulated by changes in dopamine signaling, as occurs in Parkinson's disease as well as addiction. Although CaMKII has b
Externí odkaz:
https://doaj.org/article/c6e9de7145f7401bbe18de3e0c26e8d7
Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors
Autor:
Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Yan Wu, Adam J. Moeser, George I. Mias, Alfred J. Robison, Jin He
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Yuen Gao et al. characterize deficits in brain morphology, behavior, and gene expression following genetic ablation of the histone methyltransferase, ASH1L, during brain development in mice. Their results provide new insight into links between ASH1L
Externí odkaz:
https://doaj.org/article/4b96d495f04d482b9a52d8c90fd24875
Autor:
Francisco J. Flores-Ramirez, Anapaula Themann, Jorge A. Sierra-Fonseca, Israel Garcia-Carachure, Samuel A. Castillo, Minerva Rodriguez, Omar Lira, Joshua Preciado-Piña, Brandon L. Warren, Alfred J. Robison, Sergio D. Iñiguez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The objective of this study was to evaluate whether juvenile fluoxetine (FLX) exposure induces long-term changes in baseline responses to anxiety-inducing environments, and if so, whether its re-exposure in adulthood would ameliorate this an
Externí odkaz:
https://doaj.org/article/80c4ded134d041aa88cdd77b4d2e9863
Publikováno v:
Cold Spring Harbor perspectives in biology. 14(3)
Depression and related mood disorders constitute an enormous burden on health, quality of life, and the global economy, and women have roughly twice the lifetime risk of men for experiencing depression. Here, we review sex differences in human brain
Autor:
Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Adam J. Moeser, George I. Mias, Alfred J. Robison, Yi Zhang, Jin He
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103742- (2022)
Summary: Recent clinical studies report that chromosomal 12q24.31 microdeletions are associated with autism spectrum disorder (ASD) and intellectual disability (ID). However, the causality and underlying mechanisms linking 12q24.31 microdeletions to
Externí odkaz:
https://doaj.org/article/7c4859cbe5774588b7eece70ffe4b2db
Autor:
Andrew L. Eagle, Claire E. Manning, Elizabeth S. Williams, Ryan M. Bastle, Paula A. Gajewski, Amber Garrison, Alexis J. Wirtz, Seda Akguen, Katie Brandel-Ankrapp, Wilson Endege, Frederick M. Boyce, Yoshinori N. Ohnishi, Michelle Mazei-Robison, Ian Maze, Rachel L. Neve, Alfred J. Robison
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Chronic stress is a risk factor for mood disorders, yet the molecular and circuit mechanisms of stress-induced changes are not well understood. Here, the authors report the role of the transcription factor ΔFosB in driving activity changes in respon
Externí odkaz:
https://doaj.org/article/d4b95067e74845b094227a1938275611
Autor:
Zhou Yin, Harikanth Venkannagari, Haley Lynch, Galina Aglyamova, Mukund Bhandari, Mischa Machius, Eric J. Nestler, Alfred J. Robison, Gabby Rudenko
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss , Pp 1-13 (2020)
ΔFosB is a highly stable transcription factor that accumulates in specific brain regions upon chronic exposure to drugs of abuse, stress, or seizures, and mediates lasting behavioral responses. ΔFosB reportedly heterodimerizes with JunD forming a c
Externí odkaz:
https://doaj.org/article/2ba2f505e8a0466988fa56318724b382
Autor:
Lindon J. Robison
Publikováno v:
Modern Economy. 14:510-537
Autor:
Avinash Chandran, Reagan E. Moffit, Alexandra F. DeJong Lempke, Adrian J. Boltz, Andrew S. Alexander, Hannah J. Robison, Zachary Yukio Kerr, Christy L. Collins, Erik A. Wikstrom
Publikováno v:
The American Journal of Sports Medicine. 51:169-178
Background: Epidemiological studies of lateral ankle sprains in NCAA sports are important in appraising the burden of this injury and informing prevention efforts. Purpose: To describe the epidemiology of lateral ankle sprains in NCAA sports during t