Repeated vital sign measurements in the emergency department predict patient deterioration within 72 hours: a prospective observational study

Autor: Vincent M. Quinten, Matijs van Meurs, Tycho J. Olgers, Judith M. Vonk, Jack J. M. Ligtenberg, Jan C. ter Maaten

Publikováno v: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 26, Iss 1, Pp 1-12 (2018)

Abstract Background More than one in five patients presenting to the emergency department (ED) with (suspected) infection or sepsis deteriorate within 72 h from admission. Surprisingly little is known about vital signs in relation to deterioration, e

Externí odkaz: https://doaj.org/article/ddf88f8925bb419aa52de6bc36669be9

Lfchimera

Autor: Jan G. M. Bolscher, Antoon J. M. Ligtenberg, Floris J. Bikker

Publikováno v: Biochemistry and Cell Biology, 99(1), 128-137. National Research Council of Canada
Ligtenberg, A J M, Bikker, F J & Bolscher, J G M 2021, ' Lfchimera : A synthetic mimic of the two antimicrobial domains of bovine lactoferrin ', Biochemistry and Cell Biology, vol. 99, no. 1, pp. 128-137 . https://doi.org/10.1139/bcb-2020-0285

© The author(s) or their institution(s).Saliva is essential for the maintenance of oral health. When salivary flow is impaired, the risk of various oral diseases such as caries and candidiasis increases drastically. Under healthy conditions, saliva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a5c4b57dcb9290114dee5bbb9472e
https://doi.org/10.1139/bcb-2020-0285

The Course of Skin and Serum Biomarkers of Advanced Glycation Endproducts and Its Association with Oxidative Stress, Inflammation, Disease Severity, and Mortality during ICU Admission in Critically Ill Patients: Results from a Prospective Pilot Study.

Autor: John H Meertens, Hans L Nienhuis, Joop D Lefrandt, Casper G Schalkwijk, Kristiina Nyyssönen, Jack J M Ligtenberg, Andries J Smit, Jan G Zijlstra, D J Mulder

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0160893 (2016)

Advanced glycation end products (AGEs) have been implicated in multiple organ failure, predominantly via their cellular receptor (RAGE) in preclinical studies. Little is known about the time course and prognostic relevance of AGEs in critically ill h

Externí odkaz: https://doaj.org/article/4cf5f2efc5ae4bedb3eab60ff265d8b3

The Effect of Exercise on Salivary Viscosity

Autor: Antoon J. M. Ligtenberg, Erwin H. S. Liem, Henk S. Brand, Enno C. I. Veerman

Publikováno v: Diagnostics, Vol 6, Iss 4, p 40 (2016)

A common experience after exercise is the presence of a thick and sticky saliva layer on the oral surfaces, which causes a feeling of a dry mouth. Since the salivary mucin MUC5B is responsible for the visco-elastic behavior of saliva, in the present

Externí odkaz: https://doaj.org/article/862bcd49e8cd40129a5ae7e7a1ba4eba

Polymorphonuclear neutrophil integrity and functionality are preserved when exposed to saliva

Autor: Bruno G. Loos, Antoon J. M. Ligtenberg, Enno C. I. Veerman, Sabrina T.G. Gunput, Patrick Rijkschroeff, Elena A. Nicu

Publikováno v: Rijkschroeff, P, Gunput, S T G, Ligtenberg, A J M, Veerman, E C I, Loos, B G & Nicu, E A 2018, ' Polymorphonuclear neutrophil integrity and functionality are preserved when exposed to saliva ', Archives of Oral Biology, vol. 92, pp. 68-74 . https://doi.org/10.1016/j.archoralbio.2018.04.019
Archives of Oral Biology, 92, 68-74. Elsevier
Archives of Oral Biology, 92, 68-74. Elsevier Limited

Objective Polymorphonuclear neutrophils (PMNs) are the most abundant innate immune cells and are also important effectors in the maintenance of oral health. However, little is known about the effects of saliva on the PMN. We therefore aimed to invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2de775c332e12516602e644cd52bbec
https://doi.org/10.1016/j.archoralbio.2018.04.019