Zobrazeno 1 - 10
of 2 316
pro vyhledávání: '"A J Knox"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Knowledge of remaining battery charge is fundamental to electric vehicle deployment. Accurate measurements of state-of-charge (SOC) cannot be obtained directly and estimation methods must be used instead. This requires both a good model of a
Externí odkaz:
https://doaj.org/article/4d043048e4bc43d79c87ebfacef1a93c
Autor:
J R Anderson, K Mortimer, L Pang, K M Smith, H Bailey, D B Hodgson, D E Shaw, A J Knox, T W Harrison
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160257 (2016)
BACKGROUND:Peroxisome proliferator-activated receptor gamma (PPAR-γ) is a nuclear receptor that modulates inflammation in models of asthma. To determine whether pioglitazone improves measures of asthma control and airway inflammation, we performed a
Externí odkaz:
https://doaj.org/article/123f9377020448fc90faf7664c3e2e86
Autor:
Rishyashring R. Iyer, Catherine C. Applegate, Opeyemi H. Arogundade, Sushant Bangru, Ian C. Berg, Bashar Emon, Marilyn Porras-Gomez, Pei-Hsuan Hsieh, Yoon Jeong, Yongdeok Kim, Hailey J. Knox, Amir Ostadi Moghaddam, Carlos A. Renteria, Craig Richard, Ashlie Santaliz-Casiano, Sourya Sengupta, Jason Wang, Samantha G. Zambuto, Maria A. Zeballos, Marcia Pool, Rohit Bhargava, H. Rex Gaskins
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32546- (2024)
Understanding the molecular and physical complexity of the tissue microenvironment (TiME) in the context of its spatiotemporal organization has remained an enduring challenge. Recent advances in engineering and data science are now promising the abil
Externí odkaz:
https://doaj.org/article/bd413684ef534d0492f05f355dd609c3
Autor:
Man-Fung Yuen, Scott Fung, Xiaoli Ma, Tuan T. Nguyen, Tarek Hassanein, Hie-Won Hann, Magdy Elkhashab, Ronald G. Nahass, James S. Park, Ira M. Jacobson, Walid S. Ayoub, Steven-Huy Han, Edward J. Gane, Katie Zomorodi, Ran Yan, Julie Ma, Steven J. Knox, Luisa M. Stamm, Maurizio Bonacini, Frank Weilert, Alnoor Ramji, Michael Bennett, Natarajan Ravendhran, Sing Chan, Douglas T. Dieterich, Paul Yien Kwo, Eugene R. Schiff, Ho S. Bae, Jacob Lalezari, Kosh Agarwal, Mark S. Sulkowski
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 100999- (2024)
Background & Aims: The investigational first-generation core inhibitor vebicorvir (VBR) demonstrated safety and antiviral activity over 24 weeks in two phase IIa studies in patients with chronic HBV infection. In this long-term extension study, patie
Externí odkaz:
https://doaj.org/article/79c1f480374a43d2b19433829b3f31b0
Autor:
Cha Len Lee, Mark Freeman, Kelly W. Burak, Gordon T. Moffat, Conor D. J. O’Donnell, Philip Q. Ding, Hanna Lyubetska, Brandon M. Meyers, Vallerie Gordon, Ekaterina Kosyachkova, Roxana Bucur, Winson Y. Cheung, Jennifer J. Knox, Vincent C. Tam
Publikováno v:
Cancers, Vol 16, Iss 16, p 2878 (2024)
The IMbrave150 trial established atezolizumab with bevacizumab (A+B) as standard care for hepatocellular carcinoma (HCC), recommending an esophagogastroduodenoscopy (EGD) within 6 months of treatment initiation to prevent bleeding from esophagogastri
Externí odkaz:
https://doaj.org/article/f1fa92983f06416981e36c47e6099ff6
Autor:
Richard S. Finn, Shukui Qin, Fabio Piscaglia, Thomas R Jeffry Evans, Jennifer J. Knox, Carlos López López, Zahra Ramji, Min Ren, Kalgi Mody, Arndt Vogel, Masatoshi Kudo
Publikováno v:
Liver Cancer (2024)
Introduction: In REFLECT, lenvatinib was noninferior to sorafenib in terms of overall survival (OS) in patients with unresectable hepatocellular carcinoma (uHCC; median 13.6 vs 12.3 months; HR 0.92, 95% CI 0.79-1.06). The objective response rate (ORR
Externí odkaz:
https://doaj.org/article/d6ae54a6e78a47678e598fa918d4b74a
Publikováno v:
mBio, Vol 15, Iss 1 (2024)
ABSTRACTThe National Summer Undergraduate Research Program (NSURP) is a mentored summer research program in biosciences for undergraduate students from underrepresented backgrounds in science, technology, engineering, and mathematics (STEM). Conducte
Externí odkaz:
https://doaj.org/article/84c7850789ff48338d1bec47bd15e223
Autor:
Ravi Ramjeesingh, Prosanto Chaudhury, Vincent C. Tam, David Roberge, Howard J. Lim, Jennifer J. Knox, Jamil Asselah, Sarah Doucette, Nirlep Chhiber, Rachel Goodwin
Publikováno v:
Current Oncology, Vol 30, Iss 8, Pp 7132-7150 (2023)
Biliary tract cancers (BTC) are rare and aggressive tumors with poor prognosis. Radical surgery offers the best chance for cure; however, most patients present with unresectable disease, and among those receiving curative-intent surgery, recurrence r
Externí odkaz:
https://doaj.org/article/d675e5bc97264225a33cf325df2fb002
Autor:
Travis Zack, Kurt P. Losert, Samantha M. Maisel, Jennifer Wild, Amin Yaqubie, Michael Herman, Jennifer J. Knox, Robert J. Mayer, Alan P. Venook, Atul Butte, Allison F. O’Neill, Ghassan K. Abou-Alfa, John D. Gordan
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract The incidence and biochemical consequences of rare tumor subtypes are often hard to study. Fibrolamellar liver cancer (FLC) is a rare malignancy affecting adolescents and young adults. To better characterize the incidence and biochemical con
Externí odkaz:
https://doaj.org/article/a6be12a913714c2aaed7398302e34be1
Autor:
James T. Topham, Erica S. Tsang, Joanna M. Karasinska, Andrew Metcalfe, Hassan Ali, Steve E. Kalloger, Veronika Csizmok, Laura M. Williamson, Emma Titmuss, Karina Nielsen, Gian Luca Negri, Sandra E. Spencer Miko, Gun Ho Jang, Robert E. Denroche, Hui-li Wong, Grainne M. O’Kane, Richard A. Moore, Andrew J. Mungall, Jonathan M. Loree, Faiyaz Notta, Julie M. Wilson, Oliver F. Bathe, Patricia A. Tang, Rachel Goodwin, Gregg B. Morin, Jennifer J. Knox, Steven Gallinger, Janessa Laskin, Marco A. Marra, Steven J. M. Jones, David F. Schaeffer, Daniel J. Renouf
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
KRAS wildtype metastatic pancreatic ductal adenocarcinoma (mPDAC) could represent a distinct molecular entity from other PDACs. Here, the authors analyse KRAS wildtype mPDAC tumours using genomics and transcriptomics and find molecular similarities w
Externí odkaz:
https://doaj.org/article/14e83fbde8ea418ebe058f1c83ca1f44