Immunogenicity and reactogenicity of SARS-CoV-2 vaccines in people living with HIV in the Netherlands: A nationwide prospective cohort study.

Autor: Kathryn S Hensley, Marlou J Jongkees, Daryl Geers, Corine H GeurtsvanKessel, Yvonne M Mueller, Virgil A S H Dalm, Grigorios Papageorgiou, Hanka Steggink, Alicja Gorska, Susanne Bogers, Jan G den Hollander, Wouter F W Bierman, Luc B S Gelinck, Emile F Schippers, Heidi S M Ammerlaan, Marc van der Valk, Marit G A van Vonderen, Corine E Delsing, Elisabeth H Gisolf, Anke H W Bruns, Fanny N Lauw, Marvin A H Berrevoets, Kim C E Sigaloff, Robert Soetekouw, Judith Branger, Quirijn de Mast, Adriana J J Lammers, Selwyn H Lowe, Rory D de Vries, Peter D Katsikis, Bart J A Rijnders, Kees Brinkman, Anna H E Roukens, Casper Rokx

Publikováno v: PLoS Medicine, Vol 19, Iss 10, p e1003979 (2022)

BackgroundVaccines can be less immunogenic in people living with HIV (PLWH), but for SARS-CoV-2 vaccinations this is unknown. In this study we set out to investigate, for the vaccines currently approved in the Netherlands, the immunogenicity and reac

Externí odkaz: https://doaj.org/article/9ad594b98b274203b73f9a4dbe6a6859

The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice.

Autor: Alex F de Vos, Mark C Dessing, Adriana J J Lammers, Alexander P N A de Porto, Sandrine Florquin, Onno J de Boer, Regina de Beer, Sanne Terpstra, Hester J Bootsma, Peter W Hermans, Cornelis van 't Veer, Tom van der Poll

Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0118181 (2015)

Toll-like receptors (TLR) and the downstream adaptor protein MyD88 are considered crucial for protective immunity during bacterial infections. Streptococcus (S.) pneumoniae is a human respiratory pathogen and a large majority of clinical pneumococcal

Externí odkaz: https://doaj.org/article/d80b3c2742ac4e1081d1dc30e8b62baf

Leven zonder milt

Autor: A J J Lammers

Publikováno v: Nederlands Tijdschrift voor Tandheelkunde. 117:611-614

The spleen plays a significant role in the defence against infections, especially infections caused by encapsulated bacteria, such as Streptococcus pneumoniae. In case of (functional) asplenia, a fulminant sepsis with a high mortality rate may develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcb8e42fb71e7d105055badfba0825d1
https://doi.org/10.5177/ntvt.2010.12.10195

Assessment of splenic function

Autor: Joost B. L. Hoekstra, I. J. M. ten Berge, A. J. J. Lammers, A. P. N. A. de Porto, Peter Speelman, Roelof J. Bennink

Publikováno v: European Journal of Clinical Microbiology & Infectious Diseases
European journal of clinical microbiology & infectious diseases, 29(12), 1465-1473. Springer Verlag

Hyposplenic patients are at risk of overwhelming post-splenectomy infection (OPSI), which carries mortality of up to 70%. Therefore, preventive measures are warranted. However, patients with diminished splenic function are difficult to identify. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e2aba9964b37a8c5c76887b5e443ac
https://doi.org/10.1007/s10096-010-1049-1

Eosinophilia à deux: a brain nagging souvenir from the Philippines

Autor: M. van Vugt, Martin P. Grobusch, D. van de Beek, T. van Gool, Aldert Bart, Abraham Goorhuis, A. J. J. Lammers

Publikováno v: Infection, 43(5), 615-617. Urban und Vogel

Angiostrongylus cantonensis is the most common cause of eosinophilic meningitis. Although a rare condition among travelers, increased travel and global transportation of food products may result in more cases across non-endemic, developed countries i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238c802896e12ae75ccaf6b366b4f16e
https://pure.amc.nl/en/publications/eosinophilia-a-deux-a-brain-nagging-souvenir-from-the-philippines(faeba4cb-c9a5-40c8-95f4-2b6026b96bdd).html