Zobrazeno 1 - 7
of 7
pro vyhledávání: '"A J Fucello"'
Autor:
A J Fucello, L K Jolliffe, E. S. Woodle, J. R. Thistlethwaite, Frank P. Stuart, Jeffrey A. Bluestone
Publikováno v:
Transplantation. 52:361-368
Several problems remain associated with anti-CD3 monoclonal antibody therapy, including first-dose reactions, recurrent rejection, and the host humoral response to the xenogeneic mAb. One approach toward optimization of anti-CD3 mAb therapy involves
Effect of isoelectric point on biodistribution and inflammation imaging with indium-111-labelled IgG
Autor:
Ban-An Khaw, L. Du, C. I. Ten Kate, D. Riexinger, Robert A. Wilkinson, Robert H. Rubin, H W Strauss, A. J. Fucello, Alan J. Fischman
Publikováno v:
European Journal of Nuclear Medicine. 17:305-309
Electrostatic effects play an important role in protein interactions and may alter the biodistribution of antibodies. To study the effect of molecular charge of the biodistribution and infection imaging properties of human polyclonal immunoglobulin G
Autor:
A J, Fischman, A J, Fucello, J L, Pellegrino-Gensey, J, Geltofsky, M L, Yarmush, R H, Rubin, H W, Strauss
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 33(7)
Radiolabeled human polyclonal IgG localizes at focal sites of infection/inflammation. Previous studies have sought to identify the mechanism of localization, but the relative importance of specific antigen recognition by individual antibody molecules
Publikováno v:
Transplantation. 52(2)
Several problems remain associated with anti-CD3 monoclonal antibody therapy, including first-dose reactions, recurrent rejection, and the host humoral response to the xenogeneic mAb. One approach toward optimization of anti-CD3 mAb therapy involves
Autor:
A J, Fischman, M C, Pike, D, Kroon, A J, Fucello, D, Rexinger, C, ten Kate, R, Wilkinson, R H, Rubin, H W, Strauss
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 32(3)
Four DTPA-derivatized chemotactic peptide analogs: ForNleLFNleYK-DTPA (P1), ForMLFNH(CH2)6NH-DTPA (P2), ForNleLFK(NH2)-DTPA (P3), and ForNleLFK-DTPA (P4), were synthesized and evaluated for in vitro bioactivity and receptor binding. The peptides were
Publikováno v:
Transplantation proceedings. 19(1 Pt 3)
Publikováno v:
Nephron. 46
Antimouse antibody is produced from 40 to 68% of the time after administration of Orthoclone OKT3. In patients treated with OKT3, however, if the concomitant immunosuppression is not decreased, the incidence of the antibody production is reduced to 4