Výsledky vyhledávání - "A J E Vulink"

Akademický článek

High-dose alkylating chemotherapy in BRCA-altered triple-negative breast cancer: the randomized phase III NeoTN trial

Publikováno v: npj Breast Cancer, Vol 9, Iss 1, Pp 1-9 (2023)

Abstract Exploratory analyses of high-dose alkylating chemotherapy trials have suggested that BRCA1 or BRCA2-pathway altered (BRCA-altered) breast cancer might be particularly sensitive to this type of treatment. In this study, patients with BRCA-alt

Externí odkaz: https://doaj.org/article/8df2c3c9b54e4fdaa94ca1a2ca82efc6

Zobrazit plný text záznamu

Discontinuation of adjuvant endocrine therapy and impact on quality of life and functional status in older patients with breast cancer

Autor: Annelieke A. Lemij, Nienke A. de Glas, Marloes G. M. Derks, Esther Bastiaannet, Jos W. S. Merkus, Titia E. Lans, Carmen C. van der Pol, Thijs van Dalen, Annelie J. E. Vulink, Leander van Gerven, Onno R. Guicherit, Eugenie M. H. Linthorst-Niers, Frederiek van den Bos, Judith R. Kroep, Gerrit Jan Liefers, Johanneke E. A. Portielje

Publikováno v: Breast Cancer Research and Treatment, 193, 567-577. SPRINGER
Breast cancer research and treatment, 193(3), 567-577. Springer New York

Purpose Side effects are the main reason for discontinuation of adjuvant endocrine therapy in older adults. The aim of this study was to examine geriatric predictors of treatment discontinuation of adjuvant endocrine therapy within the first 2 years

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f264eae5daa2fba28aaa1fcc95b32ffb
https://doi.org/10.1007/s10549-022-06583-7

Zobrazit plný text záznamu

Effects of the Moderate CYP3A4 Inhibitor Erythromycin on the Pharmacokinetics of Palbociclib

Autor: Hilde Rosing, Stijn L.W. Koolen, Laura Molenaar-Kuijsten, Annelie J E Vulink, Niels de Vries, Ron H.J. Mathijssen, Stefanie L. Groenland, Marloes G J van Dongen, Alwin D. R. Huitema, C. Louwrens Braal, Neeltje Steeghs, Jos H. Beijnen

Publikováno v: Clinical Pharmacology and Therapeutics, 111(2), 477-484. Wiley-Blackwell

Palbociclib is an oral inhibitor of cyclin-dependent kinases 4 and 6 used in the treatment of locally advanced and metastatic breast cancer, and is extensively metabolized by cytochrome P450 enzyme 3A4 (CYP3A4). A pharmacokinetic/pharmacodynamic rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c6bd2e721c934241b5a8cddea185eb
https://doi.org/10.1002/cpt.2455

Zobrazit plný text záznamu

Physical Function and Physical Activity in Older Breast Cancer Survivors: 5-Year Follow-Up from the Climb Every Mountain Study

Autor: Annelieke A Lemij, Gerrit Jan Liefers, Marloes G M Derks, Esther Bastiaannet, Marta Fiocco, Titia E Lans, Carmen C van der Pol, Annelie J E Vulink, Leander van Gerven, Onno R Guicherit, Eugenie M H Linthorst-Niers, Jos W S Merkus, Thijs van Dalen, Johanneke E A Portielje, Nienke A de Glas

Publikováno v: The Oncologist.

BackgroundA decline in physical activity and the ability to perform activities of daily living (ADL) and instrumental activities of daily living (IADL) could interfere with independent living and quality of life in older patients, but may be prevente

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ad83dffcfb65edbefa954cd5182aaee
https://doi.org/10.1093/oncolo/oyad027

Zobrazit plný text záznamu

Phase 1 study to evaluate the safety of reducing the prophylactic dose of dexamethasone around docetaxel infusion in patients with prostate and breast cancer

Autor: Rieneke T. Lugtenberg, Stefanie de Groot, Danny Houtsma, Vincent O. Dezentjé, Annelie J. E. Vulink, Maarten J. Fischer, Johanneke E. A. Portielje, Jacobus J. M. van der Hoeven, Hans Gelderblom, Hanno Pijl, Judith R. Kroep

Publikováno v: Cancers, 15(6). MDPI
Cancers; Volume 15; Issue 6; Pages: 1691

Simple Summary: Docetaxel has been approved as an anti-cancer agent in 1995. High rates of hypersensitivity reactions (HSR) and fluid retention were observed when this agent was first introduced. The use of high dose systemic corticosteroids around d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6dde910724a5797de220c309b36eaf
https://hdl.handle.net/1887/3619418

Zobrazit plný text záznamu

Predicting postoperative complications and their impact on quality of life and functional status in older patients with breast cancer

Autor: A A Lemij, W G van der Plas-Krijgsman, E Bastiaannet, J W S Merkus, T van Dalen, A J E Vulink, L van Gerven, O R Guicherit, E M H Linthorst-Niers, T E Lans, C C van der Pol, L Wyld, J L Morgan, J E A Portielje, N A de Glas, G J Liefers

Publikováno v: British Journal of Surgery. OXFORD UNIV PRESS
British Journal of Surgery

Background The percentage of older patients undergoing surgery for early-stage breast cancer has decreased over the past decade. This study aimed to develop a prediction model for postoperative complications to better inform patients about the benefi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5240cfdec7ecdc4430b7f36a0761189
https://hdl.handle.net/1887/3566660

Zobrazit plný text záznamu

Clinical outcomes of definitive chemoradiotherapy using carboplatin and paclitaxel in esophageal cancer

Autor: M.A.P. Van Ruler, D.A.R.H. Grootenboers, A J E Vulink, Marije Slingerland, Corrie A.M. Marijnen, Femke P. Peters, K J Neelis, Marta Fiocco

Publikováno v: Diseases of the Esophagus, 30(4)

Patients with nonmetastatic esophageal cancer not suitable for surgery can be treated with definitive chemoradiotherapy with curative intent. The purpose of this retrospective study is to evaluate the clinical outcomes of definitive chemoradiotherapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13470bf694e7439930d55d5510f8aadf
https://doi.org/10.1093/dote/dow033

Zobrazit plný text záznamu

Human CD1c (BDCA-1)+ myeloid dendritic cells secrete IL-10 and display an immuno-regulatory phenotype and function in response to Escherichia coli

Autor: Andrew J, Kassianos, Melinda Y, Hardy, Xinsheng, Ju, Dipti, Vijayan, Yitian, Ding, Annelie J E, Vulink, Kylie J, McDonald, Sarah L, Jongbloed, Robert B, Wadley, Christine, Wells, Derek N J, Hart, Kristen J, Radford

Publikováno v: European journal of immunology. 42(6)

Human blood myeloid DCs can be subdivided into CD1c (BDCA-1)(+) and CD141 (BDCA-3)(+) subsets that display unique gene expression profiles, suggesting specialized functions. CD1c(+) DCs express TLR4 while CD141(+) DCs do not, thus predicting that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa4929ad8c1adcda7753bb6432282559
https://pubmed.ncbi.nlm.nih.gov/22678905

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání