Zobrazeno 1 - 10
of 5 819
pro vyhledávání: '"A J Carter"'
Autor:
Xiaomei Chen, Rikard Nordgren, Stella Belin, Alzahra Hamdan, Shijun Wang, Tianwu Yang, Zhe Huang, Simon J. Carter, Simon Buatois, João A. Abrantes, Andrew C. Hooker, Mats O. Karlsson
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 10, Pp 1784-1797 (2024)
Abstract Population pharmacokinetic (PK) models are widely used to inform drug development by pharmaceutical companies and facilitate drug evaluation by regulatory agencies. Developing a population PK model is a multi‐step, challenging, and time‐
Externí odkaz:
https://doaj.org/article/7b021a7f7b66484a8b7f9eaa81834ea5
Autor:
G. Kayode, A. Howell, C. Burden, R. Margelyte, V. Cheng, M. Viner, J. Sandall, J. Carter, L. Brigante, C. Winter, F. Carroll, B. Thilaganathan, D. Anumba, A. Judge, E. Lenguerrand, Tommy’s National Centre for Maternity Improvemen t
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Preterm birth is a major cause of infant mortality and morbidity and accounts for 7–8% of births in the UK. It is more common in women from socially deprived areas and from minority ethnic groups, but the reasons for this dispar
Externí odkaz:
https://doaj.org/article/db857312e00443b6bbfb4f47c7d89685
Autor:
Harsita Patel, Michael J. Carter, Heather Jackson, Oliver Powell, Matthew Fish, Manuela Terranova-Barberio, Filomena Spada, Nedyalko Petrov, Paul Wellman, Sarah Darnell, Sobia Mustafa, Katrina Todd, Cynthia Bishop, Jonathan M. Cohen, Julia Kenny, Sarah van den Berg, Thomas Sun, Francesca Davis, Aislinn Jennings, Emma Timms, Jessica Thomas, Maggie Nyirendra, Samuel Nichols, Leire Estamiana Elorieta, Giselle D’Souza, Victoria Wright, Tisham De, Dominic Habgood-Coote, Padmanabhan Ramnarayan, Pierre Tissières, Elizabeth Whittaker, Jethro Herberg, Aubrey Cunnington, Myrsini Kaforou, Richard Ellis, Michael H. Malim, Shane M. Tibby, Manu Shankar-Hari, Michael Levin, On behalf of the DIAMONDS Consortium
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Severe febrile illnesses in children encompass life-threatening organ dysfunction caused by diverse pathogens and other severe inflammatory syndromes. A comparative approach to these illnesses may identify shared and distinct features of hos
Externí odkaz:
https://doaj.org/article/d2c0c6faa08d407fae3fa0e21cb48076
Autor:
Oliver J. Evans, Josh Norman, Liam J. Carter, Thomas Hutchinson, Andrew Don, Rosalind M. Wright, Jeffrey A. Tuhtan, Gert Toming, Jonathan D. Bolland
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Globally, catadromous freshwater eels of the genus Anguilla are of conservation concern, including critically endangered European eel (Anguilla anguilla). Pumping stations that move river water to a higher elevation severely impact eels duri
Externí odkaz:
https://doaj.org/article/505874b083df424690108b2b2f88f4d3
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Compact, high-precision inertial sensors are needed in the control schemes of many modern physics experiments to isolate them from disturbances caused by seismic motion. We present an inertial sensor whose mechanical oscillator fits on a one
Externí odkaz:
https://doaj.org/article/2c94108aed9a4495ad6c29b94e6be079
Publikováno v:
Geoscientific Model Development, Vol 17, Pp 5733-5757 (2024)
Climate models, derived from process understanding, are essential tools in the study of climate change and its wide-ranging impacts. Hindcast and future simulations provide comprehensive spatiotemporal estimates of climatology that are frequently emp
Externí odkaz:
https://doaj.org/article/be41f261fecd41be9fc68db46958d31d
Autor:
Julie Dangremond Stanton, Stephanie M. Halmo, Rayna J. Carter, Kira A. Yamini, Deborah Ososanya
Publikováno v:
Journal of Microbiology & Biology Education, Vol 25, Iss 3 (2024)
ABSTRACT Students with strong metacognitive skills are positioned to learn and achieve more than peers who are still developing their metacognition. Yet, many students come to college without well-developed metacognitive skills. As part of a longitud
Externí odkaz:
https://doaj.org/article/710e8ccfe9694ba49fdab17b2ad1695c
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
The self-association of therapeutic antibodies can result in elevated viscosity and create problems in manufacturing and formulation, as well as limit delivery by subcutaneous injection. The high concentration viscosity of some antibodies has been re
Externí odkaz:
https://doaj.org/article/1c2c74ea9eeb426685561bfdd47cda1b
Autor:
Wen-Ting K. Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J. Carter
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Bispecific antibodies, including bispecific IgG, are emerging as an important new class of antibody therapeutics. As a result, we, as well as others, have developed engineering strategies designed to facilitate the efficient production of bispecific
Externí odkaz:
https://doaj.org/article/9805ef0547804dc680ba4370dfa5869f
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Subcutaneous injection is the preferred route of administration for many antibody therapeutics for reasons that include its speed and convenience. However, the small volume limit (typically [Formula: see text]2 mL) for subcutaneous delivery often nec
Externí odkaz:
https://doaj.org/article/a50ad440254f4b97bb89e51aeaf46a98