The association of pre-operative biomarkers of endothelial dysfunction with the risk of post-operative neurocognitive disorders: results from the BioCog study

Autor: Sara Moazzen, Jürgen Janke, Arjen J. C. Slooter, Georg Winterer, Claudia Spies, Tobias Pischon, Insa Feinkohl

Publikováno v: BMC Anesthesiology, Vol 24, Iss 1, Pp 1-15 (2024)

Abstract Introduction Endothelial dysfunction (ED) promotes the development of atherosclerosis, and studies suggest an association with age-related neurocognitive disorders. It is currently unclear whether ED is also associated with the risk of perio

Externí odkaz: https://doaj.org/article/6a197ae9917142a69c9ad741dcdbf44f

Neurobiological basis and risk factors of persistent fatigue and concentration problems after COVID-19: study protocol for a prospective case–control study (VeCosCO)

Autor: Frederik Barkhof, Johanna M A Visser-Meily, Maria Prins, Janneke Horn, Menno D de Jong, Arjen J C Slooter, Caroline M van Heugten, Denise Visser, Michele van Vugt, Hanneke E Hulst, Nelleke Tolboom, Bart N M van Berckel, Dook W Koch, Godelieve de Bree, Cees C van den Wijngaard, Tessa van der Maaden, Anouk Verveen, Sander C J Verfaillie, Irene Csorba, Emma M Coomans, Brent Appelman, Ronald Boellaard, Elsmarieke M van de Giessen, Sandeep Golla, Tanja A Kuut, Yvonne M G van Os, P T Nieuwkerk, H Knoop

Publikováno v: BMJ Open, Vol 13, Iss 6 (2023)

Introduction The risk factors for persistent fatigue and cognitive complaints after infection with SARS-CoV-2 and the underlying pathophysiology are largely unknown. Both clinical factors and cognitive-behavioural factors have been suggested to play

Externí odkaz: https://doaj.org/article/e696799c650c4ba8830baf18716f9f63

Cohort profile of PLUTO: a perioperative biobank focusing on prediction and early diagnosis of postoperative complications

Autor: Johannes B Reitsma, Marc J M Bonten, Anne Marie G A de Smet, Remco de Bree, Arjen J C Slooter, Gert-Jan de Borst, Imo E Hoefer, Menno R Vriens, Jelle P Ruurda, Peter Noordzij, Lisette M Vernooij, Ronald P Zweemer, Nikki de Mul, Diede Verlaan, Wilhelmina M U van Grevenstein, Jeroen Hagendoorn, Charles Vogely, Jelle L G Haitsma Mulier, Marcel R de Zoete, Janetta Top, Jan A J Kluijtmans, Thijs Rettig, Marije Marsman, Lennie Derde, Judith van Waes, Mienke Rijsdijk, Willem Jan M Schellekens, Olaf L Cremer

Publikováno v: BMJ Open, Vol 13, Iss 4 (2023)

Purpose Although elective surgery is generally safe, some procedures remain associated with an increased risk of complications. Improved preoperative risk stratification and earlier recognition of these complications may ameliorate postoperative reco

Externí odkaz: https://doaj.org/article/8d68fc10c3e94d30b4d1e3e6deaf8592

Preoperative medication use and development of postoperative delirium and cognitive dysfunction

Autor: Maria Heinrich, Anja Nottbrock, Friedrich Borchers, Rudolf Mörgeli, Jochen Kruppa, Georg Winterer, Arjen J. C. Slooter, Claudia Spies, the BioCog Consortium

Publikováno v: Clinical and Translational Science, Vol 14, Iss 5, Pp 1830-1840 (2021)

Abstract Postoperative delirium (POD) and postoperative (neuro‐)cognitive disorder (POCD) are frequent and serious complications after operations. We aim to investigate the association between pre‐operative polypharmacy and potentially inappropri

Externí odkaz: https://doaj.org/article/e3df7062ecea49eab352c2c70f5c5963

Some Patients Are More Equal Than Others: Variation in Ventilator Settings for Coronavirus Disease 2019 Acute Respiratory Distress Syndrome

Autor: Tariq A. Dam, MD, Harm-Jan de Grooth, MD, PhD, Thomas Klausch, PhD, Lucas M. Fleuren, MD, Daan P. de Bruin, MSc, Robert Entjes, MD, Thijs C. D. Rettig, MD, PhD, Dave A. Dongelmans, MD, PhD, Age D. Boelens, MD, Sander Rigter, MD, Stefaan H. A. Hendriks, MD, Remko de Jong, MD, Marlijn J. A Kamps, MD, Marco Peters, MD, A. Karakus, MD, Diederik Gommers, MD, PhD, Dharmanand Ramnarain, MD, Evert-Jan Wils, MD, PhD, Sefanja Achterberg, MD, PhD, Ralph Nowitzky, MD, Walter van den Tempel, MD, Cornelis P. C. de Jager, MD, PhD, Fleur G. C. A. Nooteboom, MD, Evelien Oostdijk, MD, PhD, Peter Koetsier, MD, Alexander D. Cornet, MD, PhD, FRCP, Auke C. Reidinga, MD, Wouter de Ruijter, MD, PhD, Rob J. Bosman, MD, Tim Frenzel, MD, PhD, Louise C. Urlings-Strop, MD, PhD, Paul de Jong, MD, Ellen G. M. Smit, MD, Olaf L. Cremer, MD, PhD, D. Jannet Mehagnoul-Schipper, MD, PhD, Harald J. Faber, MD, Judith Lens, MD, Gert B. Brunnekreef, MD, Barbara Festen-Spanjer, MD, Tom Dormans, MD, PhD, Annemieke Dijkstra, MD, Bram Simons, MD, A. A. Rijkeboer, MD, Sesmu Arbous, MD, PhD, Marcel Aries, MD, PhD, Menno Beukema, MD, Daniël Pretorius, MD, Rutger van Raalte, MD, Martijn van Tellingen, MD, EDIC, Niels C. Gritters van den Oever, MD, Robbert C. A. Lalisang, MD, Michele Tonutti, MRes, Armand R. J. Girbes, MD, PhD, EDIC, Mark Hoogendoorn, PhD, Patrick J. Thoral, MD, EDIC, Paul W. G. Elbers, MD, PhD, EDIC, on behalf of the Dutch ICU Data Sharing Against COVID-19 Collaborators, Remko van den Akker, Tom A. Rijpstra, M. C. Reuland, Klaas Sierk Arnold, Arend Jan Meinders, Nicolas Schroten, Laura van Manen, Leon Montenij, Julia Koeter, J. W. Fijen, Jasper van Bommel, Roy van den Berg, Martha de Bruin, Roger van Rietschote, Ellen van Geest, Koen S. Simons, Anisa Hana, Joost Labout, Michael Kuiper, Albertus Beishuizen, Bart van de Gaauw, Roos Renckens, B. van den Bogaard, Peter Pickkers, Pim van der Heiden, Dennis Geutjes, Claudia (C. W.) van Gemeren, Emma Rademaker, Frits H. M. van Osch, Johan Lutisan, Jacomar J. M. van Koesveld, Bart P. Grady, Martijn de Kruif, Martin E. Haan, Luca Roggeveen, Dagmar M. Ouweneel, Ronald Driessen, Jan Peppink, G. J. Zijlstra, A. J. van Tienhoven, Evelien van der Heiden, Jan Jaap Spijkstra, Hans van der Spoel, Angelique de Man, Heder J. de Vries, Fuda van Diggelen, Ali el Hassouni, David Romero Guzman, Sandjai Bhulai, Sebastiaan J. J. Vonk, Mattia Fornasa, Tomas Machado, Adam Izdebski, Taco Houwert, Hidde Hovenkamp, Roberto Noorduijn Londono, Davide Quintarelli, Martijn G. Scholtemeijer, Aletta A. de Beer, Giovanni Cinà, Willem E. Herter, Michael de Neree tot Babberich, Olivier Thijssens, Lot Wagemakers, Hilde G. A. van der Pol, Tom Hendriks, Julie Berend, Virginia Ceni Silva, Robert F. J. Kullberg, Leo Heunks, Nicole Juffermans, Arjen J. C. Slooter, Martijn Beudel, Nicolet F. de Keizer

Publikováno v: Critical Care Explorations, Vol 3, Iss 10, p e0555 (2021)

OBJECTIVES:. As coronavirus disease 2019 is a novel disease, treatment strategies continue to be debated. This provides the intensive care community with a unique opportunity as the population of coronavirus disease 2019 patients requiring invasive m

Externí odkaz: https://doaj.org/article/32f239460e134af0a3cea6a1b4ef0a1c