Zobrazeno 1 - 10
of 83
pro vyhledávání: '"A J Abrunhosa"'
Autor:
Catarina I. G. Pinto, André D. M. Branco, Sara Bucar, Alexandra Fonseca, Antero J. Abrunhosa, Cláudia L. da Silva, Joana F. Guerreiro, Filipa Mendes
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background Glioblastoma is an extremely aggressive malignant tumor with a very poor prognosis. Due to the increased proliferation rate of glioblastoma, there is the development of hypoxic regions, characterized by an increased concentration
Externí odkaz:
https://doaj.org/article/fb07ff3d769046bc8ef6dbf895b15980
Autor:
Sara F.F. Almeida, Liliana Santos, Gabriela Sampaio-Ribeiro, Hugo R.S. Ferreira, Nuno Lima, Rui Caetano, Mónica Abreu, Mónica Zuzarte, Ana Sofia Ribeiro, Artur Paiva, Tânia Martins-Marques, Paulo Teixeira, Rui Almeida, José Manuel Casanova, Henrique Girão, Antero J. Abrunhosa, Célia M. Gomes
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background Lung metastasis is the most adverse clinical factor and remains the leading cause of osteosarcoma-related death. Deciphering the mechanisms driving metastatic spread is crucial for finding open therapeutic windows for successful o
Externí odkaz:
https://doaj.org/article/2ba18eea1a9d4b39afe0032c0bc02775
Autor:
Sergio J. C. do Carmo, Ângela C. B. Neves, Eric Kral, Jean-Michel Geets, Benoit Nactergal, Antero J. Abrunhosa, Francisco Alves
Publikováno v:
Instruments, Vol 8, Iss 3, p 38 (2024)
The implementation of the Variable Energy (VE) feature in the previously fixed-energy IBA Cyclone® Kiube cyclotron is presented as an upgrade enabling the production of novel radioisotopes with improved radionuclidic purity and production yields. Th
Externí odkaz:
https://doaj.org/article/23b0a9f49a874c13ab6ade65896d0408
Autor:
Inês C. F. Fonseca, Mariana Lapo Pais, Fábio M. S. Rodrigues, José Sereno, Miguel Castelo-Branco, Cláudia Cavadas, Mariette M. Pereira, Antero J. Abrunhosa
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 474 (2024)
Neuropeptide Y (NPY) is one of the most abundant peptides in the central nervous system of mammals and is involved in several physiological processes through NPY Y1, Y2, Y4 and Y5 receptors. Of those, the Y2 receptor has particular relevance for its
Externí odkaz:
https://doaj.org/article/9a7cc3037cdf4417b0c11ae063dde911
Autor:
Diana Cocioabă, Alexandra I. Fonseca, Radu Leonte, Ivanna Hrynchak, Roxana Tudoroiu-Cornoiu, Sergio J. C. do Carmo, Bogdan Burghelea, Simona Băruță, Ana Rita Almeida, Radu Șerban, Anca Dinischiotu, Antero J. Abrunhosa, Dana Niculae
Publikováno v:
Molecules, Vol 29, Iss 6, p 1390 (2024)
On the verge of a theranostic approach to personalised medicine, copper-64 is one of the emerging radioisotopes in nuclear medicine due to its exploitable nuclear and biochemical characteristics. The increased demand for copper-64 for preclinical and
Externí odkaz:
https://doaj.org/article/65aa69a591734cd7a2fe00914b4c8230
Autor:
Ivanna Hrynchak, Diana Cocioabă, Alexandra I. Fonseca, Radu Leonte, Sérgio J. C. do Carmo, Roxana Cornoiu, Amílcar Falcão, Dana Niculae, Antero J. Abrunhosa
Publikováno v:
Molecules, Vol 28, Iss 12, p 4670 (2023)
Antibody and nanobody-based copper-64 radiopharmaceuticals are increasingly being proposed as theranostic tools in multiple human diseases. While the production of copper-64 using solid targets has been established for many years, its use is limited
Externí odkaz:
https://doaj.org/article/2baf189e8d844e77878f52becd51db8c
Autor:
Ângela C. B. Neves, Ivanna Hrynchak, Inês Fonseca, Vítor H. P. Alves, Mariette M. Pereira, Amílcar Falcão, Antero J. Abrunhosa
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-19 (2021)
Abstract The neurotracer 6-[18F] FDOPA has been, for many years, a powerful tool in PET imaging of neuropsychiatric diseases, movement disorders and brain malignancies. More recently, it also demonstrated good results in the diagnosis of other malign
Externí odkaz:
https://doaj.org/article/1c01afc15ef04c6397a64225cdc1ab92
Autor:
Alexandra I. Fonseca, Vítor H. Alves, Sérgio J. C. do Carmo, Magda Silva, Ivanna Hrynchak, Francisco Alves, Amílcar Falcão, Antero J. Abrunhosa
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 723 (2022)
PET imaging has gained significant momentum in the last few years, especially in the area of oncology, with an increasing focus on metal radioisotopes owing to their versatile chemistry and favourable physical properties. Copper-61 (t1/2 = 3.33 h, 61
Externí odkaz:
https://doaj.org/article/a2e0fb73e4574e5a99ea2c4ff6442773
Publikováno v:
Molecules, Vol 27, Iss 12, p 3726 (2022)
Neuropeptide Y (NPY) is a vastly studied biological peptide with numerous physiological functions that activate the NPY receptor family (Y1, Y2, Y4 and Y5). Moreover, these receptors are correlated with the pathophysiology of several diseases such as
Externí odkaz:
https://doaj.org/article/0554ab14cc0c4f7a8d043b05cb5b44c8
Autor:
Catarina I. G. Pinto, Sara Bucar, Vítor Alves, Alexandra Fonseca, Antero J. Abrunhosa, Cláudia L. da Silva, Joana F. Guerreiro, Filipa Mendes
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Prostate cancer (PCa) is the second most common cancer type in men, and in advanced metastatic stages is considerable incurable. This justifies the need for efficient early diagnostic methods and novel therapies, particularly radiopharmaceuticals wit
Externí odkaz:
https://doaj.org/article/7c33e91262f746b991a2370762239b60