Zobrazeno 1 - 10
of 555
pro vyhledávání: '"A J, Workman"'
Autor:
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S. Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J. Workman, Dario A. A. Vignali, Ulrike C. Muller, Cong Liu, Han Seok Ko, Valina L. Dawson, Ted M. Dawson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/59a521d03e984273bb3d708b36d570e9
Autor:
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S. Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J. Workman, Dario A. A. Vignali, Ulrike C. Muller, Cong Liu, Han Seok Ko, Valina L. Dawson, Ted M. Dawson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Pathologic α-synuclein (α-syn) spreads from cell-to-cell, in part, through binding to the lymphocyte-activation gene 3 (Lag3). Here we report that amyloid β precursor-like protein 1 (Aplp1) interacts with Lag3 that facilitates the binding
Externí odkaz:
https://doaj.org/article/a51c0a5470e944f6b5b546f3fa48e34f
Autor:
Chan Chen, Ramhari Kumbhar, Hu Wang, Xiuli Yang, Kundlik Gadhave, Cyrus Rastegar, Yasuyoshi Kimura, Adam Behensky, Sumasri Kotha, Grace Kuo, Sruthi Katakam, Deok Jeong, Liang Wang, Anthony Wang, Rong Chen, Shu Zhang, Lingtao Jin, Creg J. Workman, Dario A. A. Vignali, Olga Pletinkova, Hongpeng Jia, Weiyi Peng, David W. Nauen, Philip C. Wong, Javier Redding‐Ochoa, Juan C. Troncoso, Mingyao Ying, Valina L. Dawson, Ted M. Dawson, Xiaobo Mao
Publikováno v:
Advanced Science, Vol 11, Iss 16, Pp n/a-n/a (2024)
Abstract The spread of prion‐like protein aggregates is a common driver of pathogenesis in various neurodegenerative diseases, including Alzheimer's disease (AD) and related Tauopathies. Tau pathologies exhibit a clear progressive spreading pattern
Externí odkaz:
https://doaj.org/article/145c90cce75b4410b097bed388733661
Autor:
Bruno Gomes, Huarlen Ogélio, Fabiane Brant, Camila Jesus Pereira-Pinto, Michael J. Workman, Monique Costa, José Bento Pereira Lima, Ademir Jesus Martins, Marcelo Ramalho-Ortigao, Ravi Durvasula, Ivy Hurwitz, Mariana Rocha David, Fernando Ariel Genta
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Background Botanical substances such as essential oils (EOs) have demonstrated insecticidal properties and are a valid option for vector control. However, free EOs are unreliable as mosquito larvicides due their easy degradation by environme
Externí odkaz:
https://doaj.org/article/ff24a5d1c98a41e2a9cc844d5999464b
Autor:
Thomas A. Anyorigiya, Sandra Castel, Katya Mauff, Frank Atuguba, Bernhards Ogutu, Abraham Oduro, David Dosoo, Kwaku-Poku Asante, Seth Owusu-Agyei, Alexander Dodoo, Abraham Hodgson, Fred Binka, Lesley J. Workman, Elizabeth N. Allen, Paolo Denti, Lubbe Wiesner, Karen I. Barnes
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-15 (2021)
Abstract Background Accurate measurement of anti-malarial drug concentrations in therapeutic efficacy studies is essential to distinguish between inadequate drug exposure and anti-malarial drug resistance, and to inform optimal anti-malarial dosing i
Externí odkaz:
https://doaj.org/article/644b2bab3f6a40269f45dfed47507949
Autor:
Behnam Keshavarz, Nathan E. Richards, Lisa J. Workman, Jaimin Patel, Lyndsey M. Muehling, Glenda Canderan, Deborah D. Murphy, Savannah G. Brovero, Samuel M. Ailsworth, Will H. Eschenbacher, Emily C. McGowan, Barbara J. Mann, Michael R. Nelson, Alexandra Kadl, Judith A. Woodfolk, Thomas A.E. Platts-Mills, Jeffrey M. Wilson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Three COVID-19 vaccines have received FDA-authorization and are in use in the United States, but there is limited head-to-head data on the durability of the immune response elicited by these vaccines. Using a quantitative assay we studied binding IgG
Externí odkaz:
https://doaj.org/article/f4a83396663b422295ffe601e519ff3a
Autor:
Michael J. Workman, Clive N. Svendsen
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-10 (2020)
Abstract The blood–brain barrier (BBB) is a critical component of the central nervous system that protects neurons and other cells of the brain parenchyma from potentially harmful substances found in peripheral circulation. Gaining a thorough under
Externí odkaz:
https://doaj.org/article/3e4eb519a1274e89a95fbc654d46a281
Autor:
Michael J. Workman, Bruno Gomes, Ju-Lin Weng, Linnea K. Ista, Camila P. Jesus, Mariana R. David, Marcelo Ramalho-Ortigao, Fernando A. Genta, Scott K. Matthews, Ravi Durvasula, Ivy Hurwitz
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Background Effective mosquito control approaches incorporate both adult and larval stages. For the latter, physical, biological, and chemical control have been used with varying results. Successful control of larvae has been demonstrated usi
Externí odkaz:
https://doaj.org/article/98d15d5faf7c46f783a66ec36c4f4ce5
Autor:
Tanyaporn Pattarabanjird, Jeffrey M. Wilson, Loren D. Erickson, Lisa J. Workman, Hui Qiao, Yanal Ghosheh, Rishab Gulati, Chistopher Durant, Jenifer Vallejo, Ryosuke Saigusa, Thomas A. E. Platts-Mills, Angela M. Taylor, Klaus Ley, Coleen A. McNamara
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Background: Recent studies have suggested that IgE sensitization to α-gal is associated with coronary artery disease (CAD). However, the B cell subtype(s) responsible for production of IgE to α-gal and mechanisms mediating this production remain el
Externí odkaz:
https://doaj.org/article/fdd20fd874ad4accbfddcc64261a926c
Autor:
V. Alexandra Moser, Michael J. Workman, Samantha J. Hurwitz, Rachel M. Lipman, Christian J. Pike, Clive N. Svendsen
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103238- (2021)
Summary: Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). APOE4 is known to affect the function of microglia, but to what extent this gene drives microglial gene expression has thus far not been
Externí odkaz:
https://doaj.org/article/fd27aedfef3942159b202a822dc10a26