Zobrazeno 1 - 10
of 2 177
pro vyhledávání: '"A J, Whelan"'
Autor:
Owen Byford, Amelia B. Shaw, Hiu Nam Tse, Alex Moon-Walker, Erica Ollmann Saphire, Sean P. J. Whelan, Martin Stacey, Roger Hewson, Juan Fontana, John N. Barr
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The Arenaviridae family of segmented RNA viruses contains nearly 70 species with several associated with fatal haemorrhagic fevers, including Lassa, Lujo and Junin viruses. Lymphocytic choriomeningitis arenavirus (LCMV) is associated with fa
Externí odkaz:
https://doaj.org/article/26962a6cb1244fc191ee31f6d4307627
Autor:
Todd Gouin, Michael J. Whelan
Publikováno v:
Microplastics and Nanoplastics, Vol 4, Iss 1, Pp 1-16 (2024)
Abstract Microplastic particles (MPs) represent potential hazards for humans and wildlife, including as vectors for chemical exposure (e.g. plastic additives and pollutants sorbed from the surrounding environment). The leaching of chemicals from MPs
Externí odkaz:
https://doaj.org/article/22a6121393514fc3af109de4824f3d6d
Autor:
Catherine A. Doyle, Gregory W. Busey, Wesley H. Iobst, Volker Kiessling, Chloe Renken, Hansa Doppalapudi, Marta E. Stremska, Mohan C. Manjegowda, Mohd Arish, Weiming Wang, Shardul Naphade, Joel Kennedy, Louis-Marie Bloyet, Cassandra E. Thompson, Paul W. Rothlauf, Eric J. Stipes, Sean P. J. Whelan, Lukas K. Tamm, Alex J. B. Kreutzberger, Jie Sun, Bimal N. Desai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The majority of viruses classified as pandemic threats are enveloped viruses which enter the cell through receptor-mediated endocytosis and take advantage of endosomal acidification to activate their fusion machinery. Here we report that the
Externí odkaz:
https://doaj.org/article/dee6605d5bdc48a684b5ee4df122fe09
Autor:
Jennifer B. Permuth, Margaret A. Park, Dung-Tsa Chen, Toni Basinski, Benjamin D. Powers, Clement K. Gwede, Kaleena B. Dezsi, Maria Gomez, Shraddha L. Vyas, Tiago Biachi, Elena M. Cortizas, Sylvia Crowder, Maria Genilo-Delgado, B.Lee Green, Anna Greene, Christopher Gregg, Sarah E. Hoffe, Kun Jiang, Bora Kim, Vanitha Vasudevan, Jeronimo Garcialopez De Llano, Anjana A. Menon, Qianxing Mo, Lina M. MorenoUrazan, Shaffer Mok, Nathan Parker, Sahana Rajasekhara, Ghulam Rasool, Andrew Sinnamon, Lauren Sparks, Paul A. Stewart, Kenneth Tardif, Alexandra F. Tassielli, Jamie K. Teer, Dan Viet Tran, Kea L. Turner, Susan T. Vadaparampil, Christopher J. Whelan, Wade G. Douglas, Vic Velanovich, Andreas Karachristos, Adrian Legaspi, Kenneth Meredith, Manual A. Molina-Vega, Kevin L. Huguet, Juan P. Arnoletti, Mark Bloomston, Jose Trevino, Nipun B. Merchant, Jose M. Pimiento, Pamela J. Hodul, Mokenge Malafa, Jason Fleming, Sarah M. Judge, Daniel K. Jeong, Andrew Judge
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionCancer-associated cachexia (CC) is a progressive syndrome characterized by unintentional weight loss, muscle atrophy, fatigue, and poor outcomes that affects most patients with pancreatic ductal adenocarcinoma (PDAC). The ability to ident
Externí odkaz:
https://doaj.org/article/99b382aea6824ea3b6624e0a14f602fd
Autor:
Amelia B. Shaw, Hiu Nam Tse, Owen Byford, Grace Plahe, Alex Moon-Walker, Samantha E. Hover, Erica Ollmann Saphire, Sean P. J. Whelan, Jamel Mankouri, Juan Fontana, John N. Barr
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Lymphocytic choriomeningitis virus (LCMV) is an enveloped and segmented negative-sense RNA virus classified within the Arenaviridae family of the Bunyavirales order. LCMV is associated with fatal disease in immunocompromised populations and,
Externí odkaz:
https://doaj.org/article/6df5a69e4c1d4c89b36dd639fa6325a6
Autor:
Sandeep Sharma, Cecilia A. Badenhorst, Donovan M. Ashby, Stephanie A. Di Vito, Michelle A. Tran, Zahra Ghavasieh, Gurleen K. Grewal, Cole R. Belway, Alexander McGirr, Patrick J. Whelan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The cuneiform nucleus (CnF) regulates locomotor activity, which is canonically viewed as being primarily involved in initiating locomotion and regulating speed. Recent research shows greater context dependency in the locomotor functions of t
Externí odkaz:
https://doaj.org/article/1c74346562b3406a8373f34dd6788ab5
Autor:
Wenjuan Dong, Jing Wang, Lei Tian, Jianying Zhang, Erik W. Settles, Chao Qin, Daniel R. Steinken-Kollath, Ashley N. Itogawa, Kimberly R. Celona, Jinhee Yi, Mitchell Bryant, Heather Mead, Sierra A. Jaramillo, Hongjia Lu, Aimin Li, Ross E. Zumwalt, Sanjeet Dadwal, Pinghui Feng, Weiming Yuan, Sean P. J. Whelan, Paul S. Keim, Bridget Marie Barker, Michael A. Caligiuri, Jianhua Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The serine protease factor Xa (FXa) is upregulated in COVID-19 patients and functions in the coagulation pathway. Here, Dong et al characterise the basis of its antiviral activity in the context of SARS-CoV-2 pandemic variants.
Externí odkaz:
https://doaj.org/article/b9e60e8540004b07b41e6a1c7eaa4a58
Autor:
Eliza K. Hanson, Rebecca J. Whelan
Publikováno v:
Sensors, Vol 24, Iss 9, p 2805 (2024)
The high affinity of the biotin–streptavidin interaction has made this non-covalent coupling an indispensable strategy for the immobilization and enrichment of biomolecular affinity reagents. However, the irreversible nature of the biotin–strepta
Externí odkaz:
https://doaj.org/article/22c1dca470a2498c9c32d2db88f11b29
Autor:
IceCube Collaboration, R. Abbasi, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, C. Alispach, A. A. Alves, N. M. Amin, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, S. Axani, X. Bai, A. V. Balagopal, A. Barbano, S. W. Barwick, B. Bastian, V. Basu, V. Baum, S. Baur, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, C. Bellenghi, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, M. A. Campana, C. Chen, D. Chirkin, S. Choi, B. A. Clark, K. Clark, L. Classen, A. Coleman, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, A. Desai, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, S. Dharani, A. Diaz, J. C. Díaz-Vélez, H. Dujmovic, M. Dunkman, M. A. DuVernois, E. Dvorak, T. Ehrhardt, P. Eller, R. Engel, J. Evans, P. A. Evenson, S. Fahey, A. R. Fazely, S. Fiedlschuster, A. T. Fienberg, K. Filimonov, C. Finley, L. Fischer, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, P. Fürst, T. K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, A. Ghadimi, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, S. Goswami, D. Grant, T. Grégoire, Z. Griffith, S. Griswold, M. Gündüz, C. Haack, A. Hallgren, R. Halliday, L. Halve, F. Halzen, M. Ha Minh, K. Hanson, J. Hardin, A. Haungs, S. Hauser, D. Hebecker, K. Helbing, F. Henningsen, S. Hickford, J. Hignight, C. Hill, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, M. Jansson, G. S. Japaridze, M. Jeong, B. J. P. Jones, R. Joppe, D. Kang, W. Kang, X. Kang, A. Kappes, D. Kappesser, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, M. Kellermann, J. L. Kelley, A. Kheirandish, J. Kim, K. Kin, T. Kintscher, J. Kiryluk, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, P. Koundal, M. Kovacevich, M. Kowalski, K. Krings, G. Krückl, N. Kulacz, N. Kurahashi, A. Kyriacou, C. Lagunas Gualda, J. L. Lanfranchi, M. J. Larson, F. Lauber, J. P. Lazar, K. Leonard, A. Leszczyńska, Y. Li, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, A. Ludwig, W. Luszczak, Y. Lyu, W. Y. Ma, J. Madsen, K. B. M. Mahn, Y. Makino, P. Mallik, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, F. McNally, K. Meagher, A. Medina, M. Meier, S. Meighen-Berger, J. Merz, J. Micallef, D. Mockler, G. Momenté, T. Montaruli, R. W. Moore, R. Morse, M. Moulai, R. Naab, R. Nagai, U. Naumann, J. Necker, G. Neer, L. V. Nguyễn, H. Niederhausen, M. U. Nisa, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, M. Oehler, A. Olivas, E. O’Sullivan, H. Pandya, D. V. Pankova, N. Park, G. K. Parker, E. N. Paudel, P. Peiffer, C. Pérez de los Heros, S. Philippen, D. Pieloth, S. Pieper, A. Pizzuto, M. Plum, Y. Popovych, A. Porcelli, M. Prado Rodriguez, P. B. Price, G. T. Przybylski, C. Raab, A. Raissi, M. Rameez, K. Rawlins, I. C. Rea, A. Rehman, R. Reimann, M. Renschler, G. Renzi, E. Resconi, S. Reusch, W. Rhode, M. Richman, B. Riedel, S. Robertson, G. Roellinghoff, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk Cantu, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Scharf, M. Schaufel, H. Schieler, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, F. G. Schröder, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, S. Shefali, M. Silva, B. Smithers, R. Snihur, J. Soedingrekso, D. Soldin, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, I. Taboada, F. Tenholt, S. Ter-Antonyan, S. Tilav, F. Tischbein, K. Tollefson, L. Tomankova, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, J. P. Twagirayezu, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, D. van Eijk, N. van Eijndhoven, D. Vannerom, J. van Santen, S. Verpoest, M. Vraeghe, C. Walck, A. Wallace, N. Wandkowsky, T. B. Watson, C. Weaver, A. Weindl, M. J. Weiss, J. Weldert, C. Wendt, J. Werthebach, M. Weyrauch, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, D. R. Williams, M. Wolf, T. R. Wood, K. Woschnagg, G. Wrede, J. Wulff, X. W. Xu, Y. Xu, J. P. Yanez, S. Yoshida, T. Yuan, Z. Zhang
Publikováno v:
European Physical Journal C: Particles and Fields, Vol 82, Iss 11, Pp 1-15 (2022)
Abstract High-energy tau neutrinos are rarely produced in atmospheric cosmic-ray showers or at cosmic particle accelerators, but are expected to emerge during neutrino propagation over cosmic distances due to flavor mixing. When high energy tau neutr
Externí odkaz:
https://doaj.org/article/b22c46e8f4cf494eaf3364d297855531
Autor:
Anand Swaminath, Marcin Wierzbicki, Sameer Parpia, Vijayananda Kundapur, Sergio Faria, Naseer Ahmed, Alexis Bujold, Khalid Hirmiz, Timothy Owen, Nelson Leong, Kevin Ramchandar, Edith Filion, Harold Lau, Robert Thompson, Brian Yaremko, Zsolt Gabos, Selma Mehiri, James R. Wright, Theodoros K. Tsakiridis, Kathryn Cline, Timothy J. Whelan
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 37, Iss , Pp 145-152 (2022)
Purpose: To report on the Stereotactic Body Radiation Therapy (SBRT) credentialing experience during the Phase III Ontario Clinical Oncology Group (OCOG) LUSTRE trial for stage I non-small cell lung cancer. Methods: Three credentialing requirements w
Externí odkaz:
https://doaj.org/article/0dfb58d755984234bc52727ca70b9654