Zobrazeno 1 - 10
of 40
pro vyhledávání: '"A J, Tuchman"'
Publikováno v:
Journal of Alzheimer's disease : JAD. 86(3)
Background: In pre-clinical studies of Alzheimer’s disease (AD) transgenic mice, bryostatin restored synaptic connections, prevented neuronal death, reduced amyloid plaques, and reduced neurofibrillary tangles. Objective: Within pre-specified cohor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953df01dd2b819159dfa6825af62aba5
https://pubmed.ncbi.nlm.nih.gov/35124654
https://pubmed.ncbi.nlm.nih.gov/35124654
Autor:
Richard E. Thompson, Elaine Grenier, Alan J. Tuchman, Martin R. Farlow, Susanne Wilke, Jeffrey Benison, Lee-Jen Wei, David Crockford, Daniel L. Alkon
Publikováno v:
Journal of Alzheimer's Disease
Background: Bryostatin-activated PKC epsilon pre-clinically induces synaptogenesis, anti-apoptosis, anti-amyloid-β oligomers, and anti-hyperphosphorylated tau. Objectives: To investigate bryostatin safety, tolerability, and efficacy to improve cogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731a0f981866acc84f00f8b3ccaf1b0f
http://europepmc.org/articles/PMC6398557
http://europepmc.org/articles/PMC6398557
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66085d85543c25519c7341e359723573
https://doi.org/10.1016/j.jalz.2018.07.020
https://doi.org/10.1016/j.jalz.2018.07.020
Publikováno v:
Alzheimer's & Dementia. 15:P1584-P1584
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a4e39de225cd0edefeedb1d7325488
https://doi.org/10.1016/j.jalz.2019.09.027
https://doi.org/10.1016/j.jalz.2019.09.027
Publikováno v:
Acta Neurologica Scandinavica. 92:161-165
Rhabomyolysis with myoglobinuria has been added relatively recently to the neurologic complications associated with the increased use of cocaine and the introduction of its alkaloid form (crack). This retrospective study reports our experience with 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7abc2719d54714b73b85196e620959f
https://doi.org/10.1111/j.1600-0404.1995.tb01032.x
https://doi.org/10.1111/j.1600-0404.1995.tb01032.x
Publikováno v:
Acta Neurologica Scandinavica. 90:124-129
Use of cocaine in the USA, has reached epidemic proportions since 1983, when "crack" was introduced, its higher potency compared with cocaine HCl has been associated with a tremendous increase in the incidence of strokes. This study reports our exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2189e405c8bee03edbc9d63398f2196
https://doi.org/10.1111/j.1600-0404.1994.tb02691.x
https://doi.org/10.1111/j.1600-0404.1994.tb02691.x
Autor:
Alan J. Tuchman, Dial Hewlett, Gary P. Wormser, Michael Daras, Shlomo Maayan, Barbara S. Koppel
Publikováno v:
Acta Neurologica Scandinavica. 71:337-353
– Central nervous system involvement occurred in 28 of 121 patients with acquired immune deficiency syndrome (AIDS). The major risk factor in this AIDS population was intravenous drug abuse (64%). A neurologic symptom or disability was the principa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9306456f119388a8a3619ba4dba0df
https://doi.org/10.1111/j.1600-0404.1985.tb03211.x
https://doi.org/10.1111/j.1600-0404.1985.tb03211.x
Autor:
J. Van Adelsberg, Glen S. Markowitz, Li Li, Vivette D. D'Agati, Yiqiang Cai, Stephen M. Factor, Jong Hoon Park, Harry Hou, Raju Kucherlapati, Stefan Somlo, Winfried Edelmann, Lin Geng, Guanqing Wu, J. Tuchman, S. Tibara
Publikováno v:
Nature Genetics. 24:75-78
PKD2, mutations in which cause autosomal dominant polycystic kidney disease (ADPKD), encodes an integral membrane glycoprotein with similarity to calcium channel subunits. We induced two mutations in the mouse homologue Pkd2 (ref.4): an unstable alle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2332f47eee8776c350aa2a21ce452b7
https://doi.org/10.1038/71724
https://doi.org/10.1038/71724
Publikováno v:
Journal of Epilepsy. 9:75-78
Phenytoin (PHT) loading is indicated for acute seizure prophylaxis. Oral loading is safer than intravenous loading but is slower and less reliable. Oral PHT loading has historically been accomplished in several divided doses because of concerns about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b299135869c07c6c32a92773d3aa61ad
https://doi.org/10.1016/0896-6974(95)00069-0
https://doi.org/10.1016/0896-6974(95)00069-0
Publikováno v:
Journal of the History of the Neurosciences. 3:233-236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a62b7abb727c3fb90031e76ab93d9ac
https://doi.org/10.1080/09647049409525616
https://doi.org/10.1080/09647049409525616