Zobrazeno 1 - 10
of 41
pro vyhledávání: '"A J, Trimboli"'
Autor:
Gina M. Sizemore, Subhasree Balakrishnan, Katie A. Thies, Anisha M. Hammer, Steven T. Sizemore, Anthony J. Trimboli, Maria C. Cuitiño, Sarah A. Steck, Gary Tozbikian, Raleigh D. Kladney, Neelam Shinde, Manjusri Das, Dongju Park, Sarmila Majumder, Shiva Krishnan, Lianbo Yu, Soledad A. Fernandez, Arnab Chakravarti, Peter G. Shields, Julia R. White, Lisa D. Yee, Thomas J. Rosol, Thomas Ludwig, Morag Park, Gustavo Leone, Michael C. Ostrowski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The tumor microenvironment influences tumor progression. Here the authors show that lack of stromal PTEN phosphatase induces DNA repair defects in the neighboring mammary gland epithelial cells via hyperactivation of EGF-receptor signaling, resulting
Externí odkaz:
https://doaj.org/article/f4113fd816a74125b1e376f6cb322dab
Autor:
Michael C. Ostrowski, Blake E. Hildreth, Gustavo W. Leone, Morag Park, Michael Hallett, Lianbo Yu, Soledad A. Fernandez, Shan K. Naidu, Gina M. Sizemore, Thierry Pécot, Anthony J. Trimboli, Julie A. Wallace Reeser, Xin Liu, Jinghai Wu
Supplementary Data from Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2308e3a914ef71eb9e9d9ab883f67a57
https://doi.org/10.1158/1541-7786.22527600.v1
https://doi.org/10.1158/1541-7786.22527600.v1
Autor:
Gustavo Leone, Michael C. Ostrowski, Charis Eng, Michael L. Robinson, Thomas J. Rosol, Nicholas Creasap, Stephan M. Tanner, Lei Shen, Guo Wei, Alain de Bruin, Koichi Fukino, Anthony J. Trimboli
Supplementary Figure Legends 1-2 from Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cd5428bb6b24ec3c4344bdf1fe227d
https://doi.org/10.1158/0008-5472.22373553.v1
https://doi.org/10.1158/0008-5472.22373553.v1
Autor:
Gustavo Leone, Michael C. Ostrowski, Charis Eng, Michael L. Robinson, Thomas J. Rosol, Nicholas Creasap, Stephan M. Tanner, Lei Shen, Guo Wei, Alain de Bruin, Koichi Fukino, Anthony J. Trimboli
Supplementary Figures 1-2 from Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2559c8a9ca89755af3888dcc744686d4
https://doi.org/10.1158/0008-5472.22373550
https://doi.org/10.1158/0008-5472.22373550
Autor:
Gustavo Leone, Michael C. Ostrowski, Charis Eng, Michael L. Robinson, Thomas J. Rosol, Nicholas Creasap, Stephan M. Tanner, Lei Shen, Guo Wei, Alain de Bruin, Koichi Fukino, Anthony J. Trimboli
We developed stromal- and epithelial-specific cre-transgenic mice to directly visualize epithelial-mesenchymal transition (EMT) during cancer progression in vivo. Using three different oncogene-driven mouse mammary tumor models and cell-fate mapping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7736a032be1dfdbe05b2030697eb25e2
https://doi.org/10.1158/0008-5472.c.6497130
https://doi.org/10.1158/0008-5472.c.6497130
Autor:
Luke Russell, Sarah A. Steck, Bhuvaneswari Ramaswamy, Daniel G. Stover, Jose Otero, Zaibo Li, Robert Pilarski, Jonathan M. Spehar, Jonathan P. Godbout, Raleigh D. Kladney, Michael C. Ostrowski, Gustavo Leone, Gina M. Sizemore, Steven T. Sizemore, Arnab Chakravarti, Maria C. Cuitiño, Blake E. Hildreth, Christopher Koivisto, Anisha M. Hammer, Lynn Schoenfield, Manjusri Das, Katie A. Thies, Anthony J. Trimboli, Jennifer A. Geisler, Chelsea Bolyard, Matthew D. Ringel, Balveen Kaur, Jerome F. Bey
Publikováno v:
Cancer Research. 81:606-618
Platelet-derived growth factor receptor-beta (PDGFRβ) is a receptor tyrosine kinase found in cells of mesenchymal origin such as fibroblasts and pericytes. Activation of this receptor is dependent on paracrine ligand induction, and its preferred lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5dd524112bcd03fb8667bb601420a71
https://doi.org/10.1158/0008-5472.can-19-3731
https://doi.org/10.1158/0008-5472.can-19-3731
Autor:
Julie A Wallace, Fu Li, Subhasree Balakrishnan, Carmen Z Cantemir-Stone, Thierry Pecot, Chelsea Martin, Raleigh D Kladney, Sudarshana M Sharma, Anthony J Trimboli, Soledad A Fernandez, Lianbo Yu, Thomas J Rosol, Paul C Stromberg, Robert Lesurf, Michael Hallett, Morag Park, Gustavo Leone, Michael C Ostrowski
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71533 (2013)
Tumor fibroblasts are active partners in tumor progression, but the genes and pathways that mediate this collaboration are ill-defined. Previous work demonstrates that Ets2 function in stromal cells significantly contributes to breast tumor progressi
Externí odkaz:
https://doaj.org/article/0d4bcc502f7c4211a33d43fcc4b6843f
Autor:
Michael C. Ostrowski, Lynn Schoenfield, Gina M. Sizemore, Sarah A. Steck, Chelsea Bolyard, Manjusri Das, Arnab Chakravarti, Luke Russell, Anthony J. Trimboli, Balveen Kaur, Anisha M. Hammer, Jose Otero, Raleigh D. Kladney, Gustavo Leone, Robert Pilarski, Steven T. Sizemore, Matthew D. Ringel, Blake E. Hildreth, Katie A. Thies
Publikováno v:
Cancer Research. 79:PD9-11
PDGFRβ is a receptor tyrosine kinase found in cells of mesenchymal origin such as fibroblasts and pericytes. Activation of this receptor is dependent on paracrine ligand induction, and its preferred ligand, PDGFB, is released by neighboring epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4998202804374459fba44bd4c9311007
https://doi.org/10.1158/1538-7445.sabcs18-pd9-11
https://doi.org/10.1158/1538-7445.sabcs18-pd9-11
Autor:
Maria C. Cuitiño, Santiago Acero-Bedoya, Marilly Palettas, Julie A. Stephens, Bhuvaneswari Ramaswamy, Jo L. Freudenheim, Daniel G. Stover, Christopher Koivisto, Mustafa M. Basree, Jianying Zhang, Sarmila Majumder, Gina M. Sizemore, Peter G. Shields, Allen Zhang, Anthony J. Trimboli, Gustavo Leone, Thomas Ludwig, Daniel Weng, Neelam Shinde, Raleigh D. Kladney, Hee Kyung Kim, Ramesh K. Ganju
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 21, Iss 1, Pp 1-18 (2019)
Breast Cancer Research, Vol 21, Iss 1, Pp 1-18 (2019)
Background A large collaborative analysis of data from 47 epidemiological studies concluded that longer duration of breastfeeding reduces the risk of developing breast cancer. Despite the strong epidemiological evidence, the molecular mechanisms link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48df3c589732a5828e430ffc17a45f0d
http://europepmc.org/articles/PMC6637535
http://europepmc.org/articles/PMC6637535
Autor:
Lisa D. Yee, Michael C. Ostrowski, Subhasree Balakrishnan, Shiva Krishnan, Sarah A. Steck, Thomas J. Rosol, Peter G. Shields, Sarmila Majumder, Neelam Shinde, Gary Tozbikian, Maria C. Cuitiño, Morag Park, Manjusri Das, Julia White, Lianbo Yu, Anisha M. Hammer, Gustavo Leone, Katie A. Thies, Steven T. Sizemore, Arnab Chakravarti, Dongju Park, Raleigh D. Kladney, Soledad Fernandez, Thomas Ludwig, Gina M. Sizemore, Anthony J. Trimboli
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The importance of the tumor–associated stroma in cancer progression is clear. However, it remains uncertain whether early events in the stroma are capable of initiating breast tumorigenesis. Here, we show that in the mammary glands of non-tumor bea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e728ef4557be0c6f11c9703f2c0fa013
http://europepmc.org/articles/PMC6050339
http://europepmc.org/articles/PMC6050339