Zobrazeno 1 - 10
of 15
pro vyhledávání: '"A J, Tomolonis"'
Autor:
Victor E. Pricolo, Shea C. Gregg, Richard J. Tomolonis, David A. Iannitti, William W. Mayo-Smith, William G. Cioffi
Publikováno v:
Digestive surgery. 20(4)
Background: Portal vein gas (PVG) has historically been associated with mortality rates of 75% or higher and mandatory abdominal exploration. The following study reassesses the clinical significance of gas in the portal venous system detected by comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2240b510177b7938944b04ff8e5e89ed
https://pubmed.ncbi.nlm.nih.gov/12806196
https://pubmed.ncbi.nlm.nih.gov/12806196
Autor:
Dallas M. Green, Karl G. Untch, Wendell H. Rooks, Albert J. Tomolonis, James Patrick Dunn, Peter H. Nelson
Publikováno v:
Journal of Medicinal Chemistry. 20:1557-1562
The syntheses and antiinflammatory assays of some dibenztroponeacetic and -propionic acids and derivatives are described. The most potent compound, d-2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)propionic acid, has a potency of ca, 70 times phenylbutazone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e41a6f060ea3cbd34eb6ecd40c0e8a0
https://doi.org/10.1021/jm00222a004
https://doi.org/10.1021/jm00222a004
Publikováno v:
Agents and Actions. 10:266-273
Tiopinac displayed marked anti-inflammatory activity when given p.o. in rat models of acute and chronic inflammation. It inhibited carrageenan-induced paw edema (40 x phenylbutazone), and cotton-pellet-induced granuloma (0.8 x indomethacin). In an 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc342eb35d6ed7c99f591a6eaf71ed0f
https://doi.org/10.1007/bf02025946
https://doi.org/10.1007/bf02025946
Autor:
J M, Muchowski, E, Galeazzi, R, Greenhouse, A, Guzmán, V, Peréz, N, Ackerman, S A, Ballaron, J R, Rovito, A J, Tomolonis, J M, Young
Publikováno v:
Journal of Medicinal Chemistry. 32:1202-1207
5-Aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carb oxylic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids were synthesized and assayed as antiinflammatory and analgesic agents. The majority of these compounds exhibit a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3358609500e27ed1c0289d373c26e25
https://doi.org/10.1021/jm00126a010
https://doi.org/10.1021/jm00126a010
Autor:
Brian. Lewis, Wendell H. Rooks, John H Fried, Ian T. Harrison, A. P. Roszkowski, Peter H. Nelson, Albert J. Tomolonis
Publikováno v:
Journal of Medicinal Chemistry. 13:203-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22763acc257646341e432f35b82adc27
https://doi.org/10.1021/jm00296a008
https://doi.org/10.1021/jm00296a008
Autor:
Gabriel Garay, Angel Guzman, Wendell H. Rooks, Joseph M. Muchowski, Albert J. Tomolonis, Esperanza Velarde, Roman Davis
Publikováno v:
Journal of pharmaceutical sciences. 75(3)
11-Deoxy-11 alpha,12 alpha-methanoprostaglandin E2 (1b) and the corresponding methyl ester 7a were highly potent, but short acting, bronchodilators both by the intravenous (80 and 10 times PGE2, respectively) and aerosol (2 and approximately 1 times
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a08f6429c4948e4b4d55c86e09cb442
https://pubmed.ncbi.nlm.nih.gov/3701618
https://pubmed.ncbi.nlm.nih.gov/3701618
ChemInform Abstract: 11-Deoxy-11α,12α-methanoprostaglandin E2, a Potent, Short-Acting Bronchodilator
Autor:
Roman Davis, Esperanza Velarde, Albert J. Tomolonis, Wendell H. Rooks, Gabriel Garay, Joseph M. Muchowski, Angel Guzman
Publikováno v:
Chemischer Informationsdienst. 17
11-Deoxy-11α,12α-methanoprostaglandin E2 (1b) and the corresponding methyl ester 7a were highly potent, but short acting, bronchodilators both by the intravenous (80 and 10 times PGE2, respectively) and aerosol (2 and ~1 times PGE2) routes, as meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0728fb7b852857d6148646e93e1ee3e9
https://doi.org/10.1002/chin.198641333
https://doi.org/10.1002/chin.198641333
Autor:
A J Tomolonis, J M Young
Publikováno v:
Agents and actions. 21(3-4)
Indomethacin was administered subcutaneously to rats, 4 mg/kg/day for 4 consecutive days in order to produce erosions of the small intestine which were scored at necropsy on day 5. Orally administered phenidone (up to 250 mg/kg/day), a mixed cycloocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a9b1fc2359823d8971f3386e28a924
https://pubmed.ncbi.nlm.nih.gov/3687586
https://pubmed.ncbi.nlm.nih.gov/3687586
Publikováno v:
Agents and actions. 12(5-6)
RS-37619 showed highly potent analgesic activity when given p.o. in tests utilizing underlying inflammation. It inhibited phenylquinone-induced writhing in the mouse and rat (350 and 180 x aspirin respectively) and the pain induced by flexing the adj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b482e03ccf6c9aed9691b6e9519815
https://pubmed.ncbi.nlm.nih.gov/6984594
https://pubmed.ncbi.nlm.nih.gov/6984594
Publikováno v:
Journal of medicinal chemistry. 29(11)
A number of 7-benzoylbenzofuran-5-ylacetic acids and 7-benzoylbenzothiophene-5-ylacetic acids were synthesized. The compounds were generally only 1/2 to 3 times as potent as phenylbutazone in the rat paw edema antiinflammatory assay. However, they sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc06ce2016ff7a3794194718103e420
https://pubmed.ncbi.nlm.nih.gov/3491210
https://pubmed.ncbi.nlm.nih.gov/3491210