Zobrazeno 1 - 10
of 334
pro vyhledávání: '"A J, Smout"'
Autor:
Sujittra Chaiyadet, Sirikachorn Tangkawattana, Michael J Smout, Wannaporn Ittiprasert, Victoria H Mann, Raksawan Deenonpoe, Patpicha Arunsan, Alex Loukas, Paul J Brindley, Thewarach Laha
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010839 (2022)
Infection with the food-borne liver fluke Opisthorchis viverrini is the principal risk factor for cholangiocarcinoma (CCA) in the Mekong Basin countries of Thailand, Lao PDR, Vietnam, Myanmar and Cambodia. Using a novel model of CCA, involving infect
Externí odkaz:
https://doaj.org/article/fdd882f39a254d7a85d1ab254586a92d
Autor:
Evaristus C. Mbanefo, Chinwike Terry Agbo, Yuanlong Zhao, Olivia K. Lamanna, Kim H. Thai, Shannon E. Karinshak, Mohammad Afzal Khan, Chi-Ling Fu, Justin I. Odegaard, Irina V. Saltikova, Michael J. Smout, Luke F. Pennington, Mark R. Nicolls, Theodore S. Jardetzky, Alex Loukas, Paul J. Brindley, Franco H. Falcone, Michael H. Hsieh
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background Schistosoma haematobium, the helminth causing urogenital schistosomiasis, is a known bladder carcinogen. Despite the causal link between S. haematobium and bladder cancer, the underlying mechanisms are poorly understood. S. haemat
Externí odkaz:
https://doaj.org/article/6279d08d2cba439eb9c52b553d18d985
Autor:
Patpicha Arunsan, Apisit Chaidee, Christina J. Cochran, Victoria H. Mann, Toshihiko Tanno, Chutima Kumkhaek, Michael J. Smout, Shannon E. Karinshak, Rutchanee Rodpai, Javier Sotillo, Alex Loukas, Thewarach Laha, Paul J. Brindley, Wannaporn Ittiprasert
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 5, Pp 203-216 (2020)
Crosstalk between malignant and neighboring cells contributes to tumor growth. In East Asia, infection with the liver fluke is a major risk factor for cholangiocarcinoma (CCA). The liver fluke Opisthorchis viverrini secretes a growth factor termed li
Externí odkaz:
https://doaj.org/article/3799a2516bc54006934f1b0afa1bd439
Autor:
Casey A. Schmidt, Ira Cooke, David T. Wilson, David J. Miller, Steve Peigneur, Jan Tytgat, Matthew Field, Rozita Takjoo, Michael J. Smout, Alex Loukas, Norelle L. Daly
Publikováno v:
Journal of Natural Products. 85:1789-1798
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a08a74d7d2ced00404647140b797061
https://doi.org/10.1021/acs.jnatprod.2c00325
https://doi.org/10.1021/acs.jnatprod.2c00325
Autor:
Patpicha Arunsan, Wannaporn Ittiprasert, Michael J Smout, Christina J Cochran, Victoria H Mann, Sujittra Chaiyadet, Shannon E Karinshak, Banchob Sripa, Neil David Young, Javier Sotillo, Alex Loukas, Paul J Brindley, Thewarach Laha
Publikováno v:
eLife, Vol 8 (2019)
Infection with the food-borne liver fluke Opisthorchis viverrini is the principal risk factor (IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2012) for cholangiocarcinoma (CCA) in the Lower Mekong River Basin countries includin
Externí odkaz:
https://doaj.org/article/396bc5f294004fa185c635a8aa2ab358
Autor:
Thanapat Hembasat, Sujittra Chaiyadet, Wannaporn Ittiprasert, Michael J Smout, Neil D Young, Alex Loukas, Paul J Brindley, THEWARACH LAHA
Purpose Progranulin (PGRN) is a secreted glycoprotein growth factor with roles in wound healing, inflammation, angiogenesis and malignancy. An orthologue of the gene encoding human PGRN was identified in the carcinogenic liver fluke Opisthorchis vive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a030f1f6809a4bb2327f1ae07c27bd
https://doi.org/10.21203/rs.3.rs-2586058/v1
https://doi.org/10.21203/rs.3.rs-2586058/v1
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 5, Iss 3, Pp 141-148 (2015)
Infection with helminth parasites causes morbidity and mortality in billions of people and livestock worldwide. Where anthelmintic drugs are available, drug resistance is a major problem in livestock parasites, and a looming threat to public health.
Externí odkaz:
https://doaj.org/article/a5afad1bec7d41d38663171de5e9714e
Autor:
Rozita Takjoo, David Wilson, Paramjit S. Bansal, Alex Loukas, Michael J. Smout, Norelle L. Daly
Publikováno v:
Biomolecules, Vol 10, Iss 8, p 1152 (2020)
Granulins are a family of unique protein growth factors which are found in a range of species and have several bioactivities that include cell proliferation and wound healing. They typically contain six disulfide bonds, but the sequences, structures
Externí odkaz:
https://doaj.org/article/1be1a0c3fdb3469483fd10052d35a963
Autor:
Brandon Haugen, Shannon E. Karinshak, Victoria H. Mann, Anastas Popratiloff, Alex Loukas, Paul J. Brindley, Michael J. Smout
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
The liver fluke Opisthorchis viverrini is a food-borne, zoonotic pathogen endemic to Thailand and adjacent countries in Southeast Asia. The adult developmental stage of the O. viverrini parasite excretes and secretes numerous proteins within the bili
Externí odkaz:
https://doaj.org/article/a9b28bbc4aa445a1aa2e442a34ea66e4
Autor:
Madhu K Sundaraneedi, Bemnet A Tedla, Ramon M Eichenberger, Luke Becker, Darren Pickering, Michael J Smout, Siji Rajan, Phurpa Wangchuk, F Richard Keene, Alex Loukas, J Grant Collins, Mark S Pearson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 12, p e0006134 (2017)
Schistosomiasis affects over 200 million people and there are concerns whether the current chemotherapeutic control strategy (periodic mass drug administration with praziquantel (PZQ)-the only licenced anti-schistosome compound) is sustainable, neces
Externí odkaz:
https://doaj.org/article/092fa447a02a4f12a7290df14a2f9ef0