Zobrazeno 1 - 10
of 863
pro vyhledávání: '"A J, Segal"'
Publikováno v:
BMC Nutrition, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Background The American Heart Association (AHA) chose the REAP-S dietary screener in 2020 as one of three US dietary screeners recommended for integrating dietary assessment into clinical care. The REAP-S v.2 is an updated version that is al
Externí odkaz:
https://doaj.org/article/cc921b3ba6ee42c2a5e26fe2cefd6825
Autor:
Jesse Papenburg, Anil Adisesh, Michael Liu, Tingting Yan, Matthew P Cheng, Niklas Bobrovitz, Rahul Arora, Christian Cao, Mercedes Yanes-Lane, Claire Donnici, Nathan Duarte, Sara Perlman-Arrow, Hannah P Rahim, Emily Boucher, Sean D’Mello, Natalie Duarte, Graham Bennett, David Kodama, Natasha Illincic, Mitchell J Segal, Lucas J Penny
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Objective To describe and synthesise studies of SARS-CoV-2 seroprevalence by occupation prior to the widespread vaccine roll-out.Methods We identified studies of occupational seroprevalence from a living systematic review (PROSPERO CRD42020183634). E
Externí odkaz:
https://doaj.org/article/8a0f3b6730774e398863cd423dff8698
Autor:
Ulrika Beitnere, Brayan Vilanova-Cuevas, Sarah G. Christian, Clint Taylor, Elizabeth L. Berg, Nycole A. Copping, Scott V. Dindot, Jill L. Silverman, Mélanie G. Gareau, David J. Segal
Publikováno v:
mSystems, Vol 8, Iss 1 (2023)
ABSTRACT A large subset of patients with Angelman syndrome (AS) suffer from concurrent gastrointestinal (GI) issues, including constipation, poor feeding, and reflux. AS is caused by the loss of ubiquitin ligase E3A (UBE3A) gene expression in the bra
Externí odkaz:
https://doaj.org/article/603c826aee6f48c298a9ce88f28aaa34
Autor:
David J. Segal
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2022)
Externí odkaz:
https://doaj.org/article/4b76b56c108247ca95782b28358a48db
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2022)
An extensive arsenal of biosensing tools has been developed based on the clustered regularly interspaced short palindromic repeat (CRISPR) platform, including those that detect specific DNA sequences both in vitro and in live cells. To date, DNA imag
Externí odkaz:
https://doaj.org/article/20d965019e1643b1abd364af6fdf42ec
Autor:
Jai Woong Seo, Elizabeth S. Ingham, Lisa Mahakian, Spencer Tumbale, Bo Wu, Sadaf Aghevlian, Shahin Shams, Mo Baikoghli, Poorva Jain, Xiaozhe Ding, Nick Goeden, Tatyana Dobreva, Nicholas C. Flytzanis, Michael Chavez, Kratika Singhal, Ryan Leib, Michelle L. James, David J. Segal, R. Holland Cheng, Eduardo A. Silva, Viviana Gradinaru, Katherine W. Ferrara
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Adeno-associated viruses (AAVs) can be targeted in a tissue-specific manner, but their tissue accumulation cannot be assessed in a non-invasive manner. Here the authors conjugate a multivalent chelator labelled with Cu-64 to the surface of AAVs and i
Externí odkaz:
https://doaj.org/article/3bffb0cc262e4293b560a67f7e3c6fd9
Autor:
Peter Deng, Julian A. N. M. Halmai, Ulrika Beitnere, David Cameron, Michele L. Martinez, Charles C. Lee, Jennifer J. Waldo, Krista Thongphanh, Anna Adhikari, Nycole Copping, Stela P. Petkova, Ruth D. Lee, Samantha Lock, Miranda Palomares, Henriette O’Geen, Jasmine Carter, Casiana E. Gonzalez, Fiona K. B. Buchanan, Johnathan D. Anderson, Fernando A. Fierro, Jan A. Nolta, Alice F. Tarantal, Jill L. Silverman, David J. Segal, Kyle D. Fink
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2022)
Zinc finger (ZF), transcription activator-like effectors (TALE), and CRISPR/Cas9 therapies to regulate gene expression are becoming viable strategies to treat genetic disorders, although effective in vivo delivery systems for these proteins remain a
Externí odkaz:
https://doaj.org/article/467d6e2aab3844e6b89d37a65f30a120
Publikováno v:
Microbiota in Health and Disease, Vol 3 (2021)
As the range of disease states associated with the gut microbiome expands – and the mechanistic links between the gut microbiome and host physiology further deepens – so interest also grows in microbiome manipulation as medical therapy. In partic
Externí odkaz:
https://doaj.org/article/d133e577e4c14de8b590211119213f4d
Autor:
Henriette O’Geen, Sofie L. Bates, Sakereh S. Carter, Karly A. Nisson, Julian Halmai, Kyle D. Fink, Suhn K. Rhie, Peggy J. Farnham, David J. Segal
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-20 (2019)
Abstract Background Rewriting of the epigenome has risen as a promising alternative to gene editing for precision medicine. In nature, epigenetic silencing can result in complete attenuation of target gene expression over multiple mitotic divisions.
Externí odkaz:
https://doaj.org/article/f99d86a8bbaf4fed912b9c90925d2dd9
Autor:
Henriette O’Geen, Ulrika Beitnere, Miranda S. Garcia, Anna Adhikari, David L. Cameron, Timothy A. Fenton, Nycole A. Copping, Peter Deng, Samantha Lock, Julian A.N.M. Halmai, Isaac J. Villegas, Jiajian Liu, Danhui Wang, Kyle D. Fink, Jill L. Silverman, David J. Segal
Publikováno v:
Molecular Therapy. 31:1088-1105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37fc565f97f8d789cc2309165788f0a
https://doi.org/10.1016/j.ymthe.2023.01.013
https://doi.org/10.1016/j.ymthe.2023.01.013