Zobrazeno 1 - 10
of 18
pro vyhledávání: '"A J, Robert McGray"'
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-29 (2022)
Abstract Oncolytic viruses (OVs) represent a new class of multi-modal immunotherapies for cancer, with OV-elicited antitumor immunity being key to their overall therapeutic efficacy. Currently, the clinical effectiveness of OV as monotherapy remains
Externí odkaz:
https://doaj.org/article/4074a2360a934ab6876fef48c4fe0a6f
Autor:
Kunle Odunsi, Takemasa Tsuji, Mark Long, Danuta Kozbor, Scott I Abrams, Emese Zsiros, A J Robert McGray, Jessie L Chiello, Kathryn Maraszek, Nicole Gaulin, Spencer R Rosario, Suzanne M Hess
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background Cancer immunotherapies can produce complete therapeutic responses, however, outcomes in ovarian cancer (OC) are modest. While adoptive T-cell transfer (ACT) has been evaluated in OC, durable effects are rare. Poor therapeutic efficacy is l
Externí odkaz:
https://doaj.org/article/9b49e6bc2cfa4280884bd9b7ea9e2876
Autor:
Emad Y. Alqassim, Shraddha Sharma, A. N. M. Nazmul H. Khan, Tiffany R. Emmons, Eduardo Cortes Gomez, Abdulrahman Alahmari, Kelly L. Singel, Jaron Mark, Bruce A. Davidson, A. J. Robert McGray, Qian Liu, Brian D. Lichty, Kirsten B. Moysich, Jianmin Wang, Kunle Odunsi, Brahm H. Segal, Bora E. Baysal
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Alqassim et al find that RNA editing, known to be induced by IFN-1 in macrophages by the enzyme APOBEC3A, is required for the transcriptional, pro-inflammatory and metabolic responses that drive M1 macrophage polarization. APOBEC3A-mediated editing i
Externí odkaz:
https://doaj.org/article/8289df36f80e4288872e7c05d2e770f3
Autor:
A. J. Robert McGray, Ruea-Yea Huang, Sebastiano Battaglia, Cheryl Eppolito, Anthony Miliotto, Kyle B. Stephenson, Amit A. Lugade, Gill Webster, Brian D. Lichty, Mukund Seshadri, Danuta Kozbor, Kunle Odunsi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background Cancer immunotherapies are emerging as promising treatment strategies for ovarian cancer patients that experience disease relapse following first line therapy. As such, identifying strategies to bolster anti-tumor immunity and lim
Externí odkaz:
https://doaj.org/article/80478d4009594eabbb5adee11254fa6a
Autor:
Yali Zhang, Anthony Miliotto, Ruea-Yea Huang, Cheryl Eppolito, Jianming Wang, Adekunle Odunsi, A J Robert McGray, Adebukola Abiola
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immune checkpoint blockers (ICBs) have been approved by the Food and Drug Administration to be used alone in front-line therapies or in combination with other regimens for certain advanced cancers. Since ICB only works in a subset of patie
Externí odkaz:
https://doaj.org/article/01b53e8b84204e7e867eec1a252249a1
Autor:
Zongjie Wang, Sharif Ahmed, Mahmoud Labib, Hansen Wang, Licun Wu, Fatemeh Bavaghar-Zaeimi, Nastaran Shokri, Soraly Blanco, Saraf Karim, Kasia Czarnecka-Kujawa, Edward H. Sargent, A. J. Robert McGray, Marc de Perrot, Shana O. Kelley
Publikováno v:
Nature Biomedical Engineering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba3e9d5615841e8993f28b11bc1ac4c9
https://doi.org/10.1038/s41551-023-01023-3
https://doi.org/10.1038/s41551-023-01023-3
Autor:
Brendan Zangari, Takemasa Tsuji, Junko Matsuzaki, Hemn Mohammadpour, Cheryl Eppolito, Sebastiano Battaglia, Fumito Ito, Thinle Chodon, Richard Koya, A. J. Robert McGray, Kunle Odunsi
Publikováno v:
Cancer Immunology, Immunotherapy. 71:2881-2898
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28422963d9b2c2ebe8a099615812d3e4
https://doi.org/10.1007/s00262-022-03197-2
https://doi.org/10.1007/s00262-022-03197-2
Autor:
Gregory E. Sokolow, Matthew R. Crawley, Daniel R. Morphet, Didar Asik, Joseph A. Spernyak, A. J. Robert McGray, Timothy R. Cook, Janet R. Morrow
Publikováno v:
Inorganic Chemistry. 61:2603-2611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6e63cc92fd363ef57c072ae73899143
https://doi.org/10.1021/acs.inorgchem.1c03660
https://doi.org/10.1021/acs.inorgchem.1c03660
Autor:
Gregory E, Sokolow, Matthew R, Crawley, Daniel R, Morphet, Didar, Asik, Joseph A, Spernyak, A J Robert, McGray, Timothy R, Cook, Janet R, Morrow
Publikováno v:
Inorg Chem
A metal organic polyhedron (MOP) with four paramagnetic Fe(III) centers was studied as a magnetic resonance imaging (MRI) probe. The MOP was characterized in solution by using EPR and UV-vis spectroscopies, FT-ICR mass spectrometry, and in the solid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6945e6b4fbf6ecd0779999607699fd80
https://pubmed.ncbi.nlm.nih.gov/35073060
https://pubmed.ncbi.nlm.nih.gov/35073060
Autor:
Kunle Odunsi, Feng Qian, Amit A. Lugade, Han Yu, Melissa A. Geller, Steven P. Fling, Judith C. Kaiser, Andreanne M. Lacroix, Leonard D’Amico, Nirasha Ramchurren, Chihiro Morishima, Mary L. Disis, Lucas Dennis, Patrick Danaher, Sarah Warren, Van Anh Nguyen, Sudharshan Ravi, Takemasa Tsuji, Spencer Rosario, Wenjuan Zha, Alan Hutson, Song Liu, Shashikant Lele, Emese Zsiros, A. J. Robert McGray, Jessie Chiello, Richard Koya, Thinle Chodon, Carl D. Morrison, Vasanta Putluri, Nagireddy Putluri, Donald E. Mager, Rudiyanto Gunawan, Martin A. Cheever, Sebastiano Battaglia, Junko Matsuzaki
Publikováno v:
Sci Transl Med
To uncover underlying mechanisms associated with failure of indoleamine 2,3-dioxygenase 1 (IDO1) blockade in clinical trials, we conducted a pilot, window-of-opportunity clinical study in 17 patients with newly diagnosed advanced high-grade serous ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8e43c1970974a5d2ecf993085e3805
https://pubmed.ncbi.nlm.nih.gov/35294258
https://pubmed.ncbi.nlm.nih.gov/35294258