Zobrazeno 1 - 10
of 23
pro vyhledávání: '"A J, Okragly"'
Autor:
Angela J. Okragly, Aya Ryuzoji, Isabella Wulur, Montanea Daniels, Robert D. Van Horn, Chetan N. Patel, Robert J. Benschop
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 7, Pp 1535-1547 (2023)
Abstract Introduction IL-13 is the primary upregulated cytokine in atopic dermatitis (AD) skin and is the pathogenic mediator driving AD pathophysiology. Lebrikizumab, tralokinumab and cendakimab are therapeutic monoclonal antibodies (mAb) that targe
Externí odkaz:
https://doaj.org/article/dbd152b9d5754b53906c6ae3157c3648
Autor:
Teresa Ju, Angelina Labib, Leigh Nattkemper, Sarah Engle, Autum Auxier, Nathan Hahn, Sean Sissons, Jonathan T. Sims, Zhe Sun, Angela J. Okragly, Gil Yosipovitch
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Abstract is missing (Short communication)
Externí odkaz:
https://doaj.org/article/900ff7d1930b47eabce69544610638f6
Autor:
Varsha Parthasarathy, Karen Cravero, Junwen Deng, Zhe Sun, Sarah M. Engle, Autum N. Auxier, Nathan Hahn, Jonathan T. Sims, Angela J. Okragly, Martin P. Alphonse, Shawn G. Kwatra
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ImportancePrurigo nodularis (PN) is a chronic heterogeneous inflammatory skin disease.ObjectiveTo elucidate which components of type 2 inflammation are dysregulated systemically in PN.DesignWhole blood was obtained from PN patients with uncontrolled
Externí odkaz:
https://doaj.org/article/5555746fa38d4b13b12e24ca57522990
Autor:
Varsha Parthasarathy, Karen Cravero, Lillian Xu, Junwen Deng, Zhe Sun, Sarah M. Engle, Jonathan T. Sims, Angela J. Okragly, Shawn G. Kwatra
Publikováno v:
Journal of the American Academy of Dermatology. 88:1101-1109
Autor:
Vivian Laquer, Viviana Parra, Jean-Philippe Lacour, Hidetoshi Takahashi, Jack Knorr, Angela J. Okragly, Douglas E. James, Jonathan T. Sims, Ching-Yun Chang, Jeannie Chao, Paul Klekotka
Publikováno v:
British Journal of Dermatology. 187:599-602
Autor:
William A. Rose, Angela J. Okragly, Ningjie N. Hu, Montanea R. Daniels, Andrea P. Martin, Yi Ting Koh, Kristine Kikly, Robert J. Benschop
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Breaking tolerance is a key event leading to autoimmunity, but the exact mechanisms responsible for this remain uncertain. Here we show that the alarmin IL-33 is able to drive the generation of autoantibodies through induction of the B cell survival
Externí odkaz:
https://doaj.org/article/d1228f9ab1f94cada93acf6e5a47d8bd
Autor:
Sarah B Dicker, Tatiyana L. Shiyanova, Patel Chetankumar Natvarlal, Stephanie Marie Truhlar, Robert J. Benschop, Stuart W. Bright, Dongmei He, Oliver Schroeder, Katie Brannon Corwin, Marikka Elia, Qing Zhang, Julian Davies, Lukasz K. Chlewicki, Angela J. Okragly
Publikováno v:
Journal of Inflammation Research
Angela J Okragly,1 Katie Brannon Corwin,2 Marikka Elia,3 Dongmei He,3 Oliver Schroeder,3 Qing Zhang,3 Tatiyana Shiyanova,2 Stuart Bright,1 Sarah B Dicker,4 Lukasz Chlewicki,4 Stephanie ME Truhlar,3 Julian Davies,3 Chetan N Patel,2 Robert J Benschop1
Autor:
Heather A Bullock, Hana E. Baker, Matthew J Hamang, Angela J. Okragly, Y. Linda Ma, Jonathan Lucchesi, Andrea P. Martin, Robert J. Benschop, Emily A. Pena
Publikováno v:
Cytokine. 79:66-73
Interleukin (IL)-33 is a member of the IL-1 family. IL-33 effects are mediated through its receptor, ST2 and IL-1RAcP, and its signaling induces the production of a number of pro-inflammatory mediators, including TNFα, IL-1β, IL-6, and IFN-γ. Ther
Autor:
Ningjie N. Hu, William A. Rose, Yi Ting Koh, Kristine Kay Kikly, Angela J. Okragly, Montanea R. Daniels, Andrea P. Martin, Robert J. Benschop
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Breaking tolerance is a key event leading to autoimmunity, but the exact mechanisms responsible for this remain uncertain. Here we show that the alarmin IL-33 is able to drive the generation of autoantibodies through induction of the B cell survival
Autor:
David C. DeRosa, Angela J. Okragly, Kirk W. Johnson, Michael P. Johnson, Andrea P. Martin, Robert J. Benschop, S Michelle Morin
Publikováno v:
Cephalalgia : an international journal of headache. 38(9)
Background Many patients with migraines suffer from allergies and vice versa, suggesting a relationship between biological mechanisms of allergy and migraine. It was proposed many years ago that mast cells may be involved in the pathophysiology of mi