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Akademický článek

Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity.

Autor: Roger Pelle, Simon P Graham, Moses N Njahira, Julius Osaso, Rosemary M Saya, David O Odongo, Philip G Toye, Paul R Spooner, Anthony J Musoke, Duncan M Mwangi, Evans L N Taracha, W Ivan Morrison, William Weir, Joana C Silva, Richard P Bishop

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e19015 (2011)

Theileria parva causes an acute fatal disease in cattle, but infections are asymptomatic in the African buffalo (Syncerus caffer). Cattle can be immunized against the parasite by infection and treatment, but immunity is partially strain specific. Ava

Externí odkaz: https://doaj.org/article/3ce08aaecc574375b437ae2f7867f147

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Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus

Autor: Richard P. Bishop, Cordula Nitsch, Anthony J. Musoke, David Odongo, Stephen Mwaura, Lucy Kamau, Claudia Daubenberger, Robert A. Skilton, Evans L. N. Taracha

Publikováno v: Vaccine. 25:1287-1296

Vaccines based on recombinant Bm86 gut antigen from Boophilus microplus are a useful component of integrated control strategies against B. microplus infestations of cattle. The capacity of such vaccines to control heterologous infestations by two Afr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7d386b9b75d0426fde74d2de23525b
https://doi.org/10.1016/j.vaccine.2006.09.085

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Novel baculovirus-derived p67 subunit vaccines efficacious against East Coast fever in cattle

Autor: John Rowlands, Stephen A. Kaba, Monique M. van Oers, Just M. Vlak, Theo P.M. Schetters, Vishvanath Nene, Arno N. Vermeulen, Anthony J. Musoke, Dick Schaap

Publikováno v: Vaccine, 23(21), 2791-2800
Vaccine 23 (2005) 21

Two novel baculovirus-derived recombinant Theileria parva p67 constructs were tested for their vaccine potential against East Coast fever. Boran calves were immunized with a his-GFP-p67 fusion protein (GFP:p67deltaSS) or with GP64:p67C, a protein fus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cfdc558a6859b387c36e96cf827c97
https://doi.org/10.1016/j.vaccine.2004.10.043

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Bovine Leukocyte Antigen Major Histocompatibility Complex Class IIDRB3*2703andDRB3*1501Alleles Are Associated with Variation in Levels of Protection againstTheileria parvaChallenge following Immunization with the Sporozoite p67 Antigen

Autor: Keith T. Ballingall, Anthony Luyai, Subash P. Morzaria, G. John Rowlands, Anthony J. Musoke, Declan J. McKeever, Jill Sales

Publikováno v: Infection and Immunity. 72:2738-2741

Initial laboratory trials of an experimental subunit vaccine againstTheileria parvabased on the 67-kDa major sporozoite surface antigen revealed a range of responses to challenge. We have analyzed convergence in seven sets of monozygotic twins which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aedef4a70508ca853174b2c50486a180
https://doi.org/10.1128/iai.72.5.2738-2741.2004

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Confirmation and dissection of QTL controlling resistanceto malaria in mice

Autor: Anthony J. Musoke, Sonal Nagda, O.K. Ole-MoiYoi, Maria Hernandez-Valladares, Jan Naessens, Pascal Rihet, Fuad A. Iraqi, John P. Gibson

Publikováno v: Mammalian Genome. 15:390-398

We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49edf04329bbe5de3a22058e1497699a
https://doi.org/10.1007/s00335-004-3042-4

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Monoclonal Antibody Binding to a Surface-Exposed Epitope on Cowdria ruminantium That Is Conserved among Eight Strains

Autor: Travis C. McGuire, Anderson N. Wambugu, John Sitienei, Clive Wells, Fred R. Rurangirwa, Anthony J. Musoke, Sankale Shompole, Suman M. Mahan, Duncan Mwangi

Publikováno v: Clinical Diagnostic Laboratory Immunology. 7:983-986

Monoclonal antibodies (MAb) binding to Cowdria ruminantium elementary bodies (EB) were identified by enzyme-linked immunosorbent assay, and surface binding of one MAb (446.15) to intact EB was determined by immunofluorescence, immunogold labeling, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9b8a56dfb018a1be81a8b4d6183382
https://doi.org/10.1128/cdli.7.6.983-986.2000

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A Rab1 homologue with a novel isoprenylation signal provides insight into the secretory pathway of Theileria parva

Autor: Richard P. Bishop, Clive Wells, Rozmin Janoo, Anthony J. Musoke

Publikováno v: Molecular and Biochemical Parasitology. 102:131-143

As a first step in developing compartment-specific markers for protein trafficking within Theileria parva, we have isolated cDNAs encoding homologues of the small GTP binding proteins Rab1 and Rab4. The T. parva homologue of Rab1 (TpRab1), a protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbf3d9e6d3ff62ad0f1563ebaf50be5
https://doi.org/10.1016/s0166-6851(99)00093-6

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