Zobrazeno 1 - 10
of 13 910
pro vyhledávání: '"A J, Murphy"'
Autor:
Zahraa S. Al-Taie, Simon J. Coles, Aileen Congreve, Dylan Ford, Lucy Green, Peter N. Horton, Leigh F. Jones, Pippa Kett, Rolf Kraehenbuehl, Patrick J. Murphy, Graham J. Tizzard, Niles B. Willmore, Oliver T. Wright
Publikováno v:
Reactions, Vol 5, Iss 3, Pp 567-586 (2024)
N-alkylated C2-symmetric amino acid amide derivatives were shown to catalyse the Michael addition of 2-hydroxy-1,4-napthoquinone to β-nitrostyrene, achieving a maximum ee of 44%. The corresponding trifluoroacetic acid salts also catalysed the aldol
Externí odkaz:
https://doaj.org/article/2e058adf8e1e4961b8135f679ae6da19
Autor:
Dimitri Daldegan-Bueno, Carina Joy Donegan, Anna Forsyth, Rachael Louise Sumner, Robin J. Murphy, David B. Menkes, William Evans, Nicholas Hoeh, Frederick Sundram, Lisa M. Reynolds, Rhys Ponton, Alana Cavadino, Todd Smith, Partha Roop, Nathan Allen, Binu Abeysinghe, Darren Svirskis, Mahima Bansal, Suresh Muthukumaraswamy
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Major depressive disorder (MDD) poses a significant global health burden with available treatments limited by inconsistent efficacy and notable side effects. Classic psychedelics, including lysergic acid diethylamide (LSD), have g
Externí odkaz:
https://doaj.org/article/70cd426a594a4075b74f8e1ff6061e30
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-10 (2024)
Abstract We conducted a high-resolution study of lead in an urban moss, Orthotrichum lyellii, to better understand lead distributions and sources in Portland, Oregon (United States). The outdoor lead landscape is found to be heterogenous, with lead c
Externí odkaz:
https://doaj.org/article/85ee249bdad04f07bbd6f938f6278024
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Regenerative potential is governed by a complex process of transcriptional reprogramming, involving chromatin reorganization and dynamics in transcription factor binding patterns throughout the genome. The degree to which chromatin and epige
Externí odkaz:
https://doaj.org/article/91bd966c9e0f4dd186dd0f806506d69b
Autor:
Kailyn Valido, BS, Vandan Patel, DO, Michael J. Murphy, BS, Muhammad H. Junejo, MD, Devisha K. Patel, DO, Alana Deutsch, MD, Noel Turner, MD, Theodore D. Zaki, MD, Brett King, MD, PhD, William Damsky, MD, PhD, Caroline A. Nelson, MD
Publikováno v:
JAAD Case Reports, Vol 48, Iss , Pp 49-53 (2024)
Externí odkaz:
https://doaj.org/article/d23467c42d2e480b9e2a99a4f82551f3
Autor:
Denis J. Murphy
Publikováno v:
Earth, Vol 5, Iss 2, Pp 195-213 (2024)
In the global carbon cycle, atmospheric carbon emissions, both ‘natural’ and anthropogenic, are balanced by carbon uptake (i.e., sequestration) that mostly occurs via photosynthesis, plus a much smaller proportion via geological processes. Since
Externí odkaz:
https://doaj.org/article/07e47a114cce4944bd2463a94b059f3e
Autor:
Kimberly Conteddu, Holly M. English, Andrew W. Byrne, Bawan Amin, Laura L. Griffin, Prabhleen Kaur, Virginia Morera-Pujol, Kilian J. Murphy, Michael Salter-Townshend, Adam F. Smith, Simone Ciuti
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-21 (2024)
Abstract Zoonotic diseases represent a significant societal challenge in terms of their health and economic impacts. One Health approaches to managing zoonotic diseases are becoming more prevalent, but require novel thinking, tools and cross-discipli
Externí odkaz:
https://doaj.org/article/ecb3014557df473c8f0393190988944b
Autor:
Dmitry A. Kretov, Leighton Folkes, Alexandra Mora-Martin, Isha A. Walawalkar, Imrat, Noreen Syedah, Kim Vanuytsel, Simon Moxon, George J. Murphy, Daniel Cifuentes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Differentiation of stem and progenitor cells is a highly regulated process that involves the coordinated action of multiple layers of regulation. Here we show how the post-transcriptional regulatory layer instructs the level of chromatin reg
Externí odkaz:
https://doaj.org/article/12c9809215524e7283c8840d491bb1be
Autor:
Esperanza Muñoz-Muela, María Trujillo-Rodríguez, Ana Serna-Gallego, Abraham Saborido-Alconchel, Carmen Gasca-Capote, Ana Álvarez-Ríos, Ezequiel Ruiz-Mateos, Dmitri Sviridov, Andrew J. Murphy, Man K.S. Lee, Luis F. López-Cortés, Alicia Gutiérrez-Valencia
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105338- (2024)
Summary: Background: Among people living with HIV-1 (PHIV), immunological non-responders (INR) experience incomplete immune recovery despite suppressive antiretroviral treatment (ART), facing more severe non-AIDS events than immunological responders
Externí odkaz:
https://doaj.org/article/47ad10b8ca9a4c4b83f25cd317d658ff
Autor:
Craig P. Collins, Lam T. Khuat, Gail D. Sckisel, Logan V. Vick, Christine M. Minnar, Cordelia Dunai, Catherine T. Le, Brendan D. Curti, Marka Crittenden, Alexander Merleev, Michael Sheng, Nelson J. Chao, Emanual Maverakis, Spencer R. Rosario, Arta M. Monjazeb, Bruce R. Blazar, Dan L. Longo, Robert J. Canter, William J. Murphy
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The thymus is the central organ involved with T-cell development and the production of naïve T cells. During normal aging, the thymus undergoes marked involution, reducing naïve T-cell output and resulting in a predominance of long-lived memory T c
Externí odkaz:
https://doaj.org/article/1e288536df9248b1a327800dd3a6007e