Zobrazeno 1 - 10
of 135
pro vyhledávání: '"A J, Minn"'
Autor:
Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis I. Verginadis, Andrea R. Daniel, Danielle N. Burner, Lucy M. Driver, Sloane Satow, Stephanie Hasapis, Reem Ghinnagow, Lixia Luo, Yan Ma, Laura D. Attardi, Constantinos Koumenis, Andy J. Minn, Jeffrey L. Wrana, Chang-Lung Lee, David G. Kirsch
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Ionizing radiation induces cell death in the gastrointestinal (GI) epithelium by activating p53. However, p53 also prevents animal lethality caused by radiation-induced acute GI syndrome. Through single-cell RNA-sequencing of the irradiated
Externí odkaz:
https://doaj.org/article/f8259dde53cf4c8bad036795c5ff982c
Autor:
Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Chowell, Lisa M. Coussens, Daniel D. De Carvalho, David G. DeNardo, Jérôme Galon, Howard L. Kaufman, Tomas Kirchhoff, Michael T. Lotze, Jason J. Luke, Andy J. Minn, Katerina Politi, Leonard D. Shultz, Richard Simon, Vésteinn Thórsson, Joanne B. Weidhaas, Maria Libera Ascierto, Paolo Antonio Ascierto, James M. Barnes, Valentin Barsan, Praveen K. Bommareddy, Adrian Bot, Sarah E. Church, Gennaro Ciliberto, Andrea De Maria, Dobrin Draganov, Winson S. Ho, Heather M. McGee, Anne Monette, Joseph F. Murphy, Paola Nisticò, Wungki Park, Maulik Patel, Michael Quigley, Laszlo Radvanyi, Harry Raftopoulos, Nils-Petter Rudqvist, Alexandra Snyder, Randy F. Sweis, Sara Valpione, Roberta Zappasodi, Lisa H. Butterfield, Mary L. Disis, Bernard A. Fox, Alessandra Cesano, Francesco M. Marincola, Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-23 (2019)
Abstract Tumor immunology has changed the landscape of cancer treatment. Yet, not all patients benefit as cancer immune responsiveness (CIR) remains a limitation in a considerable proportion of cases. The multifactorial determinants of CIR include th
Externí odkaz:
https://doaj.org/article/864f25d06ad04690a4ef2014434f0547
Autor:
Amit Maity, Rosemarie Mick, Ramesh Rengan, Tara C. Mitchell, Ravi K. Amaravadi, Lynn M. Schuchter, Daniel A. Pryma, Dana M. Patsch, Alisha P. Maity, Andy J. Minn, Robert H. Vonderheide, John N. Lukens
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
We conducted a phase I dose-escalation trial of radiation with ipilimumab in patients with melanoma with ≥2 metastatic lesions. Here, we report the final full clinical analysis. Patients received RT (6 or 8 Gy x 2 or 3 doses) to a single lesion fol
Externí odkaz:
https://doaj.org/article/095b996398624a97bbe6f7d9f1fa3de8
Autor:
Mark D. Murphey, Matthew J. Minn, Alejandro Luiña Contreras, Kelly K. Koeller, Robert Y. Shih, Carrie Y. Inwards, Takehiko Yamaguchi
Publikováno v:
Skeletal Radiology. 52:349-363
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea504cd1cdaaae347604a06c9aab2a4f
https://doi.org/10.1007/s00256-022-04158-7
https://doi.org/10.1007/s00256-022-04158-7
Autor:
Zhaojun Zhang, Divij Mathew, Tristan Lim, Sijia Huang, E. John Wherry, Andy J. Minn, Zongming Ma, Nancy R. Zhang
Data integration to align cells across batches has become a cornerstone of most single cell data analysis pipelines, critically affecting downstream analyses. Yet, when the batches are expected to biologically differ, how much signal is erased during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29cb922295af9b887b67ec0b5f92dd9b
https://doi.org/10.1101/2023.05.05.539614
https://doi.org/10.1101/2023.05.05.539614
Autor:
James P. Grayczyk, Marisa S. Egan, Luying Liu, Emily Aunins, Meghan A. Wynosky-Dolfi, Scott Canna, Andy J. Minn, Sunny Shin, Igor E. Brodsky
Publikováno v:
bioRxiv
NLR family, apoptosis inhibitory proteins (NAIPs) detect bacterial flagellin and structurally related components of bacterial type III secretion systems (T3SS), and recruit NLR family, CARD domain containing protein 4 (NLRC4) and caspase-1 into an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab2db818611498cc590dfac6c0cade1
https://europepmc.org/articles/PMC10187295/
https://europepmc.org/articles/PMC10187295/
Autor:
Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis Verginadis, Andrea R. Daniel, Danielle N. Burner, Lucy M. Driver, Sloane Satow, Stephanie Hasapis, Reem Ghinnagow, Lixia Luo, Yan Ma, Laura D. Attardi, Costas Koumenis, Andy J Minn, Jeffrey L. Wrana, Chang-Lung Lee, David G. Kirsch
Publikováno v:
bioRxiv
Ionizing radiation induces cell death in the gastrointestinal (GI) epithelium by activating p53. However, p53 also prevents animal lethality caused by radiation-induced GI injury. Through single-cell RNA-sequencing of the irradiated mouse intestine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36630c4c6812ec55c808e0065a530c5b
https://doi.org/10.1101/2023.04.27.538576
https://doi.org/10.1101/2023.04.27.538576
Autor:
Robert H. Vonderheide, Christina Twyman-Saint Victor, Andy J. Minn, Jorge Henao-Mejia, Jonathan J. Kotzin, Hannah Dada, Andrew J. Rech
Immunotherapy in pancreatic ductal adenocarcinoma (PDA) remains a difficult clinical problem despite success in other disease types with immune checkpoint blockade (ICB) and chimeric antigen receptor T-cell therapy. Mechanisms driving immunosuppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb3596efca2f3dc0cb396dd7f12ef8d
https://doi.org/10.1158/0008-5472.c.6510188
https://doi.org/10.1158/0008-5472.c.6510188
Autor:
Robert H. Vonderheide, Christina Twyman-Saint Victor, Andy J. Minn, Jorge Henao-Mejia, Jonathan J. Kotzin, Hannah Dada, Andrew J. Rech
Supplemental Methods: Mouse strains and flow cytometry antibodies Supplemental Figure 1: Individual tumor kinetics of the unirradiated tumor in the PDA model. Tumor kinetics (mean and individual) of the irradiated tumor and survival in the B16-F10 me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3981ee8baea49c564aef73279598404e
https://doi.org/10.1158/0008-5472.22418657.v1
https://doi.org/10.1158/0008-5472.22418657.v1
Autor:
Theresa M. Busch, Amit Maity, Keith A. Cengel, Constantinos Koumenis, James Metz, Lei Dong, Eric Diffenderfer, Jennifer Huck, Enrico Radaelli, Charles-Antoine Assenmacher, Matthew Lanza, Mary Putt, Andy J. Minn, Artemis G. Hatzigeorgiou, Ling Qin, Lutian Yao, Kelley Varner, Michelle Cerullo, June Chiango, Khayrullo Shoniyozov, Ioannis I. Verginadis, Sarah Hagan, Denisa Goia, Giorgos Skoufos, Michele M. Kim, Gwendolyn M. Cramer, Ilias V. Karagounis, Anastasia Velalopoulou
Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1824ac287fe8dc74ac12e4a6395dea5b
https://doi.org/10.1158/0008-5472.22362482.v1
https://doi.org/10.1158/0008-5472.22362482.v1