Zobrazeno 1 - 10
of 36
pro vyhledávání: '"A J, Luzzio"'
Autor:
Xiaoming Zhang, William G. Dauben, Michael J. Luzzio, Shung C. Wu, Bipin Pandy, Robert T. Hendricks
Publikováno v:
Tetrahedron Letters. 36:2385-2388
Two efficient enantioselective syntheses of an A-ring precursor to 1 α,25-dihydroxyvitamin D3 have been developed. The key step in these sequences involves the stereoselective cyclopropanation of a chiral γ-alkoxy-α-diazo-β-keto ester. In one seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec2a33f13ab49da1c0977250d82668e
https://doi.org/10.1016/0040-4039(95)00284-j
https://doi.org/10.1016/0040-4039(95)00284-j
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2e3f8af6c989469e3b2a9664cbbdd3
https://doi.org/10.1002/chin.199209053
https://doi.org/10.1002/chin.199209053
Publikováno v:
The Journal of Organic Chemistry. 55:918-924
La synthese du compose du titre necessite la preparation de l'intermediaire cle suivant: 3-hydroxymethyl-6-oxo-perhydropyrano [3,4-c] pyrrole-2-carboxylate de methyl; a partir du N-methoxycarbonyl glycinate de methyl et du 4-t-butoxycrotonate d'ethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ac95ee7f3378458336f86ba42fc4d8
https://doi.org/10.1021/jo00290a023
https://doi.org/10.1021/jo00290a023
Publikováno v:
Tetrahedron Letters. 31:6969-6972
A series of unsaturated α-diazo carbonyl compounds underwent enantioselective intramolecular cyclopropanation (ee = 4–77%) when treated with an enantiomerically pure chiral copper catalyst. The nature of the diazo substrate was critical: α-diazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97308893d65b6f744a4abf3970a7a83a
https://doi.org/10.1016/s0040-4039(00)97218-6
https://doi.org/10.1016/s0040-4039(00)97218-6
Autor:
D L, Emerson, R, Bendele, E, Brown, S, Chiang, J P, Desjardins, L C, Dihel, S C, Gill, M, Hamilton, J D, LeRay, L, Moon-McDermott, K, Moynihan, F C, Richardson, B, Tomkinson, M J, Luzzio, D, Baccanari
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(7)
Lurtotecan is a clinically active water-soluble camptothecin analogue that has been formulated into a low-clearance unilamellar liposome, NX 211. Comparative studies between free drug and NX 211 have been performed assessing pharmacokinetics in nude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abc9e48a0e7831ecfb80c7a78e6ebf3f
https://pubmed.ncbi.nlm.nih.gov/10914740
https://pubmed.ncbi.nlm.nih.gov/10914740
Autor:
Micheal J. Luzzio, E. Hinnant, J. Yates, Tiechao Li, Wuyi Wang, Robert Milburn, Giorgio Attardo, Stuart A. Noble
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(13)
Novel antitumor 5,10-dihydro-5,10-dioxo-1 H -benzo[ g ]isochromene-3-carboxamides were discovered.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f398a54683099c4e594115801bebdc17
https://pubmed.ncbi.nlm.nih.gov/9873394
https://pubmed.ncbi.nlm.nih.gov/9873394
Autor:
Tona M. Gilmer, Michael J. Luzzio
Publikováno v:
Drug Discovery Today: Therapeutic Strategies. 2:297-298
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96ec39ce8cb96eaa9f085fca5957d0eb
https://doi.org/10.1016/j.ddstr.2005.11.008
https://doi.org/10.1016/j.ddstr.2005.11.008
Autor:
D L, Emerson, J M, Besterman, H R, Brown, M G, Evans, P P, Leitner, M J, Luzzio, J E, Shaffer, D D, Sternbach, D, Uehling, A, Vuong
Publikováno v:
Cancer research. 55(3)
The development of camptothecin-like compounds as inhibitors of topoisomerase I for the treatment of resistant tumors has generated clinical excitement in this new class of drugs. We have developed two novel water-soluble camptothecin analogues which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2045e2519a5e7223e015d8336d45c9f6
https://pubmed.ncbi.nlm.nih.gov/7834631
https://pubmed.ncbi.nlm.nih.gov/7834631
Autor:
Stephen T. Davis, Bill G. Benson, H. Neal Bramson, Dennis E. Chapman, Scott H. Dickerson, Karen M. Dold, Derek J. Eberwein, Mark Edelstein, Stephen V. Frye, Robert T. Gampe, Robert J. Griffin, Philip A. Harris, Anne M. Hassell, William D. Holmes, Robert N. Hunter, Victoria B. Knick, Karen Lackey, Brett Lovejoy, Michael J. Luzzio, Doris Murray, Patricia Parker, Warren J. Rocque, Lisa Shewchuk-Chapman, James M. Veal, Duncan H. Walker, Lee F. Kuyper
Publikováno v:
Science. 298:2327-2327
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd92d1c23abdea3f9ddb2a75460f951
https://doi.org/10.1126/science.298.5602.2327b
https://doi.org/10.1126/science.298.5602.2327b