Zobrazeno 1 - 10
of 280
pro vyhledávání: '"A J, Luzzio"'
Autor:
Xiaoming Zhang, William G. Dauben, Michael J. Luzzio, Shung C. Wu, Bipin Pandy, Robert T. Hendricks
Publikováno v:
Tetrahedron Letters. 36:2385-2388
Two efficient enantioselective syntheses of an A-ring precursor to 1 α,25-dihydroxyvitamin D3 have been developed. The key step in these sequences involves the stereoselective cyclopropanation of a chiral γ-alkoxy-α-diazo-β-keto ester. In one seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec2a33f13ab49da1c0977250d82668e
https://doi.org/10.1016/0040-4039(95)00284-j
https://doi.org/10.1016/0040-4039(95)00284-j
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2e3f8af6c989469e3b2a9664cbbdd3
https://doi.org/10.1002/chin.199209053
https://doi.org/10.1002/chin.199209053
Publikováno v:
The Journal of Organic Chemistry. 55:918-924
La synthese du compose du titre necessite la preparation de l'intermediaire cle suivant: 3-hydroxymethyl-6-oxo-perhydropyrano [3,4-c] pyrrole-2-carboxylate de methyl; a partir du N-methoxycarbonyl glycinate de methyl et du 4-t-butoxycrotonate d'ethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ac95ee7f3378458336f86ba42fc4d8
https://doi.org/10.1021/jo00290a023
https://doi.org/10.1021/jo00290a023
Publikováno v:
Tetrahedron Letters. 31:6969-6972
A series of unsaturated α-diazo carbonyl compounds underwent enantioselective intramolecular cyclopropanation (ee = 4–77%) when treated with an enantiomerically pure chiral copper catalyst. The nature of the diazo substrate was critical: α-diazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97308893d65b6f744a4abf3970a7a83a
https://doi.org/10.1016/s0040-4039(00)97218-6
https://doi.org/10.1016/s0040-4039(00)97218-6
Autor:
D L, Emerson, R, Bendele, E, Brown, S, Chiang, J P, Desjardins, L C, Dihel, S C, Gill, M, Hamilton, J D, LeRay, L, Moon-McDermott, K, Moynihan, F C, Richardson, B, Tomkinson, M J, Luzzio, D, Baccanari
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(7)
Lurtotecan is a clinically active water-soluble camptothecin analogue that has been formulated into a low-clearance unilamellar liposome, NX 211. Comparative studies between free drug and NX 211 have been performed assessing pharmacokinetics in nude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abc9e48a0e7831ecfb80c7a78e6ebf3f
https://pubmed.ncbi.nlm.nih.gov/10914740
https://pubmed.ncbi.nlm.nih.gov/10914740
Autor:
Micheal J. Luzzio, E. Hinnant, J. Yates, Tiechao Li, Wuyi Wang, Robert Milburn, Giorgio Attardo, Stuart A. Noble
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(13)
Novel antitumor 5,10-dihydro-5,10-dioxo-1 H -benzo[ g ]isochromene-3-carboxamides were discovered.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f398a54683099c4e594115801bebdc17
https://pubmed.ncbi.nlm.nih.gov/9873394
https://pubmed.ncbi.nlm.nih.gov/9873394
Autor:
Li, Jingjie1 (AUTHOR) jingjieli@sjtu.edu.cn, Qin, Zuoshu1 (AUTHOR), Li, Yunqi2 (AUTHOR), Huang, Baozhu1 (AUTHOR), Xiao, Qimeng1 (AUTHOR), Chen, Peiqin1 (AUTHOR), Luo, Yifan1 (AUTHOR), Zheng, Wenxin3,4,5 (AUTHOR), Zhang, Tao6 (AUTHOR) zhangtaoabc2008@sjtu.edu.cn, Zhang, Zhenbo1,7 (AUTHOR) zhangzhenbozzb@aliyun.com
Publikováno v:
Advanced Science. 6/19/2024, Vol. 11 Issue 23, p1-20. 20p.
Autor:
Tona M. Gilmer, Michael J. Luzzio
Publikováno v:
Drug Discovery Today: Therapeutic Strategies. 2:297-298
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96ec39ce8cb96eaa9f085fca5957d0eb
https://doi.org/10.1016/j.ddstr.2005.11.008
https://doi.org/10.1016/j.ddstr.2005.11.008
Autor:
D L, Emerson, J M, Besterman, H R, Brown, M G, Evans, P P, Leitner, M J, Luzzio, J E, Shaffer, D D, Sternbach, D, Uehling, A, Vuong
Publikováno v:
Cancer research. 55(3)
The development of camptothecin-like compounds as inhibitors of topoisomerase I for the treatment of resistant tumors has generated clinical excitement in this new class of drugs. We have developed two novel water-soluble camptothecin analogues which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2045e2519a5e7223e015d8336d45c9f6
https://pubmed.ncbi.nlm.nih.gov/7834631
https://pubmed.ncbi.nlm.nih.gov/7834631