Výsledky vyhledávání - "A J, Laffling"

Gene–gene interaction in folate-related genes and risk of neural tube defects in a UK population

Autor: A J Laffling, Craig S. Wilding, John Burn, Mark S. Pearce, E J Tawn, Patricia Jonas, Sally Ann Lynch, Caroline L Relton

Objective: To investigate the contribution of polymorphic variation in genes involved in the folate-dependent homocysteine pathway in the aetiology of neural tube defects (NTD). Design: Case-control association study. Subjects: A total of 530 individ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523e47ef3a539679105ec632d73e0fdd
https://europepmc.org/articles/PMC1735724/

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Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy

Autor: Terry Burgess, E. Janet Tawn, John Burn, Caroline L Relton, Keith Binks, Pat A Jonas, Craig S. Wilding, Alison J Laffling

Publikováno v: Molecular genetics and metabolism. 81(4)

Previous studies have shown conflicting findings in linking polymorphic variation in folate-related genes to the risk of neural tube defect pregnancy. Recent evidence points to maternal genotype being important in determining NTD risk. A case-control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a78f206a9567ce564123c5a01147231
https://pubmed.ncbi.nlm.nih.gov/15059614

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A monoclonal antibody that enables specific immunohistological detection of prion protein in bovine spongiform encephalopathy cases

Autor: Alison J. Laffling, Christopher R. Birkett, Alison Baird, Huw A. John

Publikováno v: Neuroscience letters. 300(2)

The specificity of a monoclonal antibody (mAB) raised against recombinant bovine prion protein (PrP) for the immunohistological detection of PrP accumulation in the medulla oblongata of bovine spongiform encephalopathy (BSE) and ovine scrapie cases w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6025fc064e111b72c84201889db9d5d2
https://pubmed.ncbi.nlm.nih.gov/11207384

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Establishment and characterization of equine autonomic ganglion cell lines to enable direct testing of candidate toxins involved in equine dysautonomia (grass sickness)

Autor: H A, John, A J, Laffling, J, Marrs, A, Baird, P S, Jat, N B, Holdstock, P D, Rossdale

Publikováno v: Cell biology and toxicology. 16(1)

To enable direct testing of a range of potential toxins or pathogens that might be involved in grass sickness, equine thoracic sympathetic chain ganglion cell lines were established from primary cell cultures by retroviral-mediated transduction of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8a88ee010e8e7f0d769d45be9d4fcb30
https://pubmed.ncbi.nlm.nih.gov/10890507

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Electrophysiological actions of phenytoin on N-methyl-D-aspartate receptor-mediated responses in rat hippocampus in vitro

Autor: Leslie Patmore, Patrick Scherr, Joseph G. McGivern, Robert D. Sheridan, Alison J. Laffling

1. The effects of the anticonvulsant, phenytoin, have been examined on N-methyl-D-aspartate (NMDA) receptor-mediated population spikes in the CA1 region of the rat hippocampus in vitro. 2. The 'conventional' (AMPA receptor-mediated) CA1 population sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d827facde2ea9531eae5d7734678624d
https://europepmc.org/articles/PMC1908748/

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