Zobrazeno 1 - 10
of 151
pro vyhledávání: '"A J, Kiliaan"'
Autor:
Lars Verschuren, Anne Linde Mak, Arianne van Koppen, Serdar Özsezen, Sonia Difrancesco, Martien P. M. Caspers, Jessica Snabel, David van der Meer, Anne-Marieke van Dijk, Elias Badal Rashu, Puria Nabilou, Mikkel Parsberg Werge, Koen van Son, Robert Kleemann, Amanda J. Kiliaan, Eric J. Hazebroek, André Boonstra, Willem P. Brouwer, Michail Doukas, Saurabh Gupta, Cornelis Kluft, Max Nieuwdorp, Joanne Verheij, Lise Lotte Gluud, Adriaan G. Holleboom, Maarten E. Tushuizen, Roeland Hanemaaijer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Accurate non-invasive biomarkers to diagnose metabolic dysfunction-associated steatotic liver disease (MASLD)-related fibrosis are urgently needed. This study applies a translational approach to develop a blood-based biomarker panel for fibr
Externí odkaz:
https://doaj.org/article/6be533e026b74a099d1ef00fbf2fcead
Autor:
Gemma Solé-Guardia, Matthijs Luijten, Bram Geenen, Jurgen A. H. R. Claassen, Geert Litjens, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda J. Kiliaan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract White matter hyperintensities (WMH) are the most prevalent markers of cerebral small vessel disease (SVD), which is the major vascular risk factor for dementia. Microvascular pathology and neuroinflammation are suggested to drive the transit
Externí odkaz:
https://doaj.org/article/7ff59429590144cd9d0b636d08691e0d
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 6, Pp 1233-1240 (2024)
Cerebral small vessel disease is a neurological disease that affects the brain microvasculature and which is commonly observed among the elderly. Although at first it was considered innocuous, small vessel disease is nowadays regarded as one of the m
Externí odkaz:
https://doaj.org/article/2c74ca9ce9e644fbb26370f7abaf7b77
Autor:
Emma Custers, Debby Vreeken, Frank Schuren, Tim J. van den Broek, Lieke van Dongen, Bram Geenen, Ivo de Blaauw, Maximilian Wiesmann, Eric J. Hazebroek, Robert Kleemann, Amanda J. Kiliaan
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 918 (2024)
Obesity is a multifactorial disease associated with low-grade inflammation. The gut is thought to be involved in obesity-related inflammation, as it is continuously exposed to antigens from food, microbiota and metabolites. However, the exact underly
Externí odkaz:
https://doaj.org/article/e42061bb6b974da9ae2228dd9c61dbcd
Autor:
M. Zuurveld, M. A. P. Diks, P. C. J. Kiliaan, J. Garssen, G. Folkerts, B. van’t Land, L. E. M. Willemsen
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundEarly life provides a window of opportunity to prevent allergic diseases. With a prevalence of 0.5–2% in infants, hen’s egg allergy is one of the most common food allergies. The immunomodulatory effects of human milk oligosaccharides (H
Externí odkaz:
https://doaj.org/article/c7a52195eb824f5086128fee88d8aa23
Autor:
Florine Seidel, Kees Fluiter, Robert Kleemann, Nicole Worms, Anita van Nieuwkoop, Martien P. M. Caspers, Nikolaos Grigoriadis, Amanda J. Kiliaan, Frank Baas, Iliana Michailidou, Martine C. Morrison
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/2b51e3ec1f034710b793571b675ff6cc
Autor:
Gemma Solé-Guardia, Emma Custers, Arthur de Lange, Elyne Clijncke, Bram Geenen, Jose Gutierrez, Benno Küsters, Jurgen A. H. R. Claassen, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda J. Kiliaan
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract The major vascular cause of dementia is cerebral small vessel disease (SVD), including white matter hyperintensities (WMH) amongst others. While the underlying pathology of SVD remains unclear, chronic hypertension and neuroinflammation are
Externí odkaz:
https://doaj.org/article/f8b63c80620f4e1d9ffcea9812722dfc
Autor:
Florine Seidel, Kees Fluiter, Robert Kleemann, Nicole Worms, Anita van Nieuwkoop, Martien P. M. Caspers, Nikolaos Grigoriadis, Amanda J. Kiliaan, Frank Baas, Iliana Michailidou, Martine C. Morrison
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionObesity has been linked to vascular dysfunction, cognitive impairment and neurodegenerative diseases. However, experimental models that recapitulate brain pathology in relation to obesity and vascular dysfunction are still lacking.Methods
Externí odkaz:
https://doaj.org/article/ce1aa71d47d747e49411fa68f117f960
Autor:
D. Komninos, L. Ramos, G. W. van der Heijden, M. C. Morrison, R. Kleemann, A. E. van Herwaarden, A. J. Kiliaan, I. A. C. Arnoldussen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Obesity can disturb spermatogenesis and subsequently affect male fertility and reproduction. In our study, we aim to elucidate at which cellular level of adult spermatogenesis the detrimental effects of obesity manifest. We induced high fat
Externí odkaz:
https://doaj.org/article/4b11370946b34dbfb4afce106fc48868
Autor:
Anouk C. Tengeler, Tim L. Emmerzaal, Bram Geenen, Vivienne Verweij, Miranda van Bodegom, Eva Morava, Amanda J. Kiliaan, Tamas Kozicz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Exposure to antibiotic treatment has been associated with increased vulnerability to various psychiatric disorders. However, a research gap exists in understanding how adolescent antibiotic therapy affects behavior and cognition. Many antibi
Externí odkaz:
https://doaj.org/article/dad546a0d8e34a448409e01707e3e61c