Zobrazeno 1 - 10
of 228
pro vyhledávání: '"A J, Kaumann"'
Autor:
Andreas Engel, Ursula Ravens, Alberto J. Kaumann, Thomas Eschenhagen, Simon Pecha, Torsten Christ, Bastiaan Geelhoed, Romy Kempe, Hermann Reichenspurner, Evaldas Girdauskas, Renate B. Schnabel, Emanuel Berk
AIM There is an increasing awareness of the impact of age and sex on cardiovascular diseases (CVDs). Differences in physiology are suspected. Beta-adrenoceptors (beta-ARs) are an important drug target in CVD and potential differences might have signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df425df662e19b90e60d9efc04ce4576
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/82460
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/82460
Autor:
Yalin Yildirim, Hermann Reichenspurner, Viacheslav O. Nikolaev, Torsten Christ, Nefeli Grammatika Pavlidou, Bernardo Dolce, Thomas Eschenhagen, Alberto J. Kaumann, Cristina E. Molina
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology
Atrial fibrillation (AF)–associated remodeling includes contractile dysfunction whose reasons are only partially resolved. Serotonin (5-HT) increases contractile force and causes arrhythmias in atrial trabeculae from patients in sinus rhythm (SR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbfdcd66cd2444cd010b722baabfa16
https://pubmed.ncbi.nlm.nih.gov/32949251
https://pubmed.ncbi.nlm.nih.gov/32949251
Publikováno v:
British Journal of Pharmacology. 174:2706-2715
Background and Purpose Mirabegron has been classified as a β3-adrenoceptor agonist approved for overactive bladder syndrome. We investigated possible cardiac effects of mirabegron in the absence or presence of β-adrenoceptor subtype antagonists. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f3f5f10d479248c6b37bc390585cdca
https://doi.org/10.1111/bph.13897
https://doi.org/10.1111/bph.13897
Autor:
Torsten Christ, Simon Schwarz, Michael Knaut, Alberto J. Kaumann, Ursula Ravens, Emanuel Berk
Publikováno v:
British Journal of Pharmacology. 173:2478-2489
Background and purpose 5-HT increases force and L-type Ca(2) (+) current (ICa,L ) and causes arrhythmias through 5-HT4 receptors in human atrium. In permanent atrial fibrillation (peAF), atrial force responses to 5-HT are blunted, arrhythmias abolish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95e31c776ac9dc8760b7943b83ae04bd
https://doi.org/10.1111/bph.13525
https://doi.org/10.1111/bph.13525
Autor:
Torsten Christ, B Geelhoed, Romy Kempe, Alberto J. Kaumann, Hermann Reichenspurner, Simon Pecha, Andreas Engel, Jussi Koivumäki, Ursula Ravens, Thomas Eschenhagen, Emanuel Berk
Publikováno v:
Acta physiologica (Oxford, England). 224(4)
acceptedVersion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b59ff46434fd7a919fac7c4e2298afe
https://pubmed.ncbi.nlm.nih.gov/21217065
https://pubmed.ncbi.nlm.nih.gov/21217065
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 389:177-186
Phosphodiesterases PDE2, PDE3, and PDE4 are expressed in murine sinoatrial cells. PDE3 and/or PDE4 reduce heart rate but apparently do not influence the tachycardia mediated through sinoatrial β1- and β2-adrenoceptors despite the high content of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0e11cd10d7b1bc2b331efe177c9c07d
https://doi.org/10.1007/s00210-015-1178-2
https://doi.org/10.1007/s00210-015-1178-2
Publikováno v:
Neurourology and Urodynamics. 34:592-597
Aims To investigate the role of the mucosa in (−)-isoprenaline-induced relaxation of mouse detrusor muscle and to characterize the β-adrenoceptor subtypes involved. Methods Isolated intact and mucosa-denuded muscle strips from the urinary bladder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea9416ea570e520656c2d7553742b48f
https://doi.org/10.1002/nau.22627
https://doi.org/10.1002/nau.22627
Autor:
Ursula Ravens, Alberto J. Kaumann, Manfred P. Wirth, Stefan Propping, Melinda Wuest, Birgit Eichhorn
Publikováno v:
BJU International. 112:1215-1222
Objectives To elucidate the impact of the mucosa on detrusor muscle function by investigating force of contraction under various stimulatory conditions and during subsequent relaxation using catecholamines. Patients and Methods Detrusor tissue was ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9a25873944d2eef0dc69336494c8786
https://doi.org/10.1111/bju.12267
https://doi.org/10.1111/bju.12267
Autor:
Alejandro Galindo-Tovar, R.I. Hussain, Peter C. M. Molenaar, Kurt A. Krobert, Torsten Christ, Katherine T. Gillette, Finn Olav Levy, Lu Chen, Emanuel Berk, Alberto J. Kaumann, Andreas Engel, Ursula Ravens
Publikováno v:
British Journal of Pharmacology. 169:528-538
Background and purpose Phosphodiesterases PDE3 and/or PDE4 control ventricular effects of catecholamines in several species but their relative effects in failing human ventricle are unknown. We investigated whether the PDE3-selective inhibitor cilost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c48d98bab8756efbf8d803fa6b8d8642
https://doi.org/10.1111/bph.12167
https://doi.org/10.1111/bph.12167
Autor:
Alberto J. Kaumann
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 386:353-356
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b65cbd196200820e060f7248e7231fb
https://doi.org/10.1007/s00210-013-0838-3
https://doi.org/10.1007/s00210-013-0838-3