Zobrazeno 1 - 10
of 2 451
pro vyhledávání: '"A J, KEATING"'
Autor:
Ronghua Zhang, Priyanka Khare, Priyanka Banerjee, Cristina Ivan, Sarah Schneider, Federica Barbaglio, Karen Clise-Dwyer, Vanessa Behrana Jensen, Erika Thompson, Marisela Mendoza, Nicholas Chiorazzi, Shih-Shih Chen, Xiao-Jie Joy Yan, Nitin Jain, Paolo Ghia, Federico Caligaris-Cappio, Rima Mendonsa, Sashi Kasimsetty, Ryan Swoboda, Recep Bayraktar, William Wierda, Varsha Gandhi, George A. Calin, Michael J. Keating, Maria Teresa Sabrina Bertilaccio
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The development and progression of chronic lymphocytic leukemia (CLL) depend on genetic abnormalities and on the immunosuppressive microenvironment. We have explored the possibility that genetic drivers might be responsible for the immune ce
Externí odkaz:
https://doaj.org/article/2643535025b44b18b47bc2931c44d1e2
Autor:
Amein K. Al-Ali, Abdullah M. Al-Rubaish, Rudaynah A. Alali, Mohammed S. Almansori, Mohammed A. Al-Jumaan, Abdullah M. Alshehri, Mohammed S. Al-Madan, ChittiBabu Vatte, Tess Cherlin, Sylvia Young, Shefali S. Verma, Grant Morahan, Bobby P. C. Koeleman, Brendan J. Keating
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Genome-wide association studies (GWAS) have yielded significant insights into the genetic architecture of myocardial infarction (MI), although studies in non-European populations are still lacking. Saudi Arabian cohorts offer an opportunity
Externí odkaz:
https://doaj.org/article/a5584b01e5674739a800aa16808ae361
Autor:
Yousef M. Alyousef, Stanley Piotrowski, Faisal A. Alonaizan, Ahmed Alsulaiman, Ali A. Alali, Naif N. Almasood, Chittibabu Vatte, Lauren Hamilton, Divya Gandla, Hetal Lad, Fred L. Robinson, Cyril Cyrus, Ryan C. Meng, Alexa Dowdell, Brian Piening, Brendan J. Keating, Amein K. Al-Ali
Publikováno v:
BMC Oral Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Oral microbiome sequencing has revealed key links between microbiome dysfunction and dental caries. However, these efforts have largely focused on Western populations, with few studies on the Middle Eastern communities. The curren
Externí odkaz:
https://doaj.org/article/c89d68a91dc943ffb596c8d8f2b73044
Publikováno v:
Sports, Vol 12, Iss 6, p 159 (2024)
We sought to investigate the lower-extremity biomechanics underlying increased gait velocity following high-cadence cycling. Ground reaction forces (GRF) and lower-extremity kinematics and kinetics were recorded as 15 healthy adults walked at a self-
Externí odkaz:
https://doaj.org/article/f8fb290c82424972bc8baa4d2a530923
Autor:
Raed M. Alsulaiman, Abdulaziz A. Al-Quorain, Fahad A. Al-Muhanna, Stanley Piotrowski, Ezzeddin A. Kurdi, Chittibabu Vatte, Ahmed A. Alquorain, Noorah H. Alfaraj, Abdulaziz M. Alrezuk, Fred Robinson, Alexa K. Dowdell, Turki A. Alamri, Lauren Hamilton, Hetal Lad, Hui Gao, Divya Gandla, Brendan J. Keating, Ryan Meng, Brian Piening, Amein K. Al-Ali
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Crohn’s diseases and ulcerative colitis, both of which are chronic immune-mediated disorders of the gastrointestinal tract are major contributors to the overarching Inflammatory bowel diseases. It has become increasingly evident
Externí odkaz:
https://doaj.org/article/32fc2a65bec745edb3b8c9007db92ce6
Autor:
Abdulrahman Alasiri, Konrad J. Karczewski, Brian Cole, Bao-Li Loza, Jason H. Moore, Sander W. van der Laan, Folkert W. Asselbergs, Brendan J. Keating, Jessica van Setten
Publikováno v:
BioData Mining, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract Background Loss-of-Function (LoF) variants in human genes are important due to their impact on clinical phenotypes and frequent occurrence in the genomes of healthy individuals. The association of LoF variants with complex diseases and trait
Externí odkaz:
https://doaj.org/article/f8e71408467d4ef6916d54391004dd44
Autor:
Abdulrahman H. Al Anazi, Ahmed S. Ammar, Mahmoud Al-Hajj, Cyril Cyrus, Danah Aljaafari, Iname Khoda, Ahmed K. Abdelfatah, Abdullah A. Alsulaiman, Firas Alanazi, Rawan Alanazi, Divya Gandla, Hetal Lad, Samar Barayan, Brendan J. Keating, Amein K. Al-Ali
Publikováno v:
Human Genomics, Vol 16, Iss 1, Pp 1-9 (2022)
Abstract Background Epilepsy, a serious chronic neurological condition effecting up to 100 million people globally, has clear genetic underpinnings including common and rare variants. In Saudi Arabia, the prevalence of epilepsy is high and caused mai
Externí odkaz:
https://doaj.org/article/54ea118cb75b460a8e7fc6cc9711aa45
Autor:
Fahad A. Al-Muhanna, Alexa K. Dowdell, Abdulmohsen H. Al Eleq, Waleed I. Albaker, Andrew W. Brooks, Ali I. Al-Sultan, Abdullah M. Al-Rubaish, Khaled R. Alkharsah, Raed M. Sulaiman, Abdulaziz A. Al-Quorain, Cyril Cyrus, Rudaynah A. Alali, Chittibabu Vatte, Fred L. Robinson, Xin Zhou, Michael P. Snyder, Afnan F. Almuhanna, Brendan J. Keating, Brian D. Piening, Amein K. Al-Ali
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Large-scale gut microbiome sequencing has revealed key links between microbiome dysfunction and metabolic diseases such as type 2 diabetes (T2D). To date, these efforts have largely focused on Western populations, with few studies
Externí odkaz:
https://doaj.org/article/c8190e3aa79d4cf3b11d0c5dd6c1129f
Autor:
Panpan Liu, Kefeng Wang, Jianan Li, Marcia A. Ogasawara, Zhongjun Xia, William G. Wierda, Michael J. Keating, Yiqing Li, Peng Huang
Publikováno v:
Haematologica, Vol 109, Iss 2 (2023)
It has been known for decades that the incidence of chronic lymphocytic leukemia (CLL) is significantly lower in Asia than in Western countries, but the reason responsible for this difference still remains a major knowledge gap. Using GeneChip® miRN
Externí odkaz:
https://doaj.org/article/7f2d42e2e1154ef885a7a0b0e3cca205
Autor:
Jocelyn M. Choo, Alyce M. Martin, Steven L. Taylor, Emily Sun, Fredrick M. Mobegi, Tokuwa Kanno, Alyson Richard, Lucy D. Burr, Stevie Lingman, Megan Martin, Damien J. Keating, A. James Mason, Geraint B. Rogers
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Long-term low-dose macrolide therapy is now widely used in the treatment of chronic respiratory diseases for its immune-modulating effects, although the antimicrobial properties of macrolides can also have collateral impacts on the gut micro
Externí odkaz:
https://doaj.org/article/8d63491e09574059afe8fa5c75bca7a8