Zobrazeno 1 - 10
of 3 479
pro vyhledávání: '"A J, Holland"'
Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity
Autor:
Marina A. Schapfl, Gina M. LoMastro, Vincent Z. Braun, Maretoshi Hirai, Michelle S. Levine, Eva Kiermaier, Verena Labi, Andrew J. Holland, Andreas Villunger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Centrioles define centrosome structure and function. Deregulation of centriole numbers can cause developmental defects and cancer. The p53 tumor suppressor limits the growth of cells lacking or harboring additional centrosomes and can be eng
Externí odkaz:
https://doaj.org/article/019d4fb19cb64cd6834d48d84c0fafe0
Autor:
Taylor Downs, Fabricio da Silva Costa, Cristiane de Freitas Paganoti, Olivia J. Holland, Deanne H. Hryciw
Publikováno v:
Endocrines, Vol 5, Iss 3, Pp 382-394 (2024)
During pregnancy, the adipokines leptin and adiponectin can affect placental nutrient transport and inflammatory pathways, potentially leading to altered fetal growth and pregnancy complications including gestational diabetes mellitus (GDM) and preec
Externí odkaz:
https://doaj.org/article/74397bc57d124c859131f2145af9f7fa
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-24 (2024)
Abstract Background Prader–Willi syndrome (PWS) is a rare and complex neurodevelopmental disorder resulting from absent paternal expression of maternally imprinted genes at chromosomal locus 15q11-13. This absence of expression occurs as a conseque
Externí odkaz:
https://doaj.org/article/1f77e9f2f6d840818bf1a8106ef865eb
Autor:
Jason A. Martin, Nicolas H. Hart, Natalie Bradford, Fiona Naumann, Mark B. Pinkham, Elizabeth P. Pinkham, Justin J. Holland
Publikováno v:
JSAMS Plus, Vol 3, Iss , Pp 100059- (2024)
Background: Sleep disturbance is a highly prevalent and impactful symptom experienced by those adversely affected by primary brain tumours. Despite this, there is a lack of literature exploring appropriate options for the management of sleep disturba
Externí odkaz:
https://doaj.org/article/30efb2fa26af477fb792fbb0be44619e
Autor:
Anna J Harte, Ehsan Ghasemian, Harry Pickering, Joanna Houghton, Ambahun Chernet, Eshetu Sata, Gizachew Yismaw, Taye Zeru, Zerihun Tadesse, E Kelly Callahan, Scott D Nash, Martin J Holland
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0012143 (2024)
Trachoma is the leading infectious cause of blindness worldwide and is now largely confined to around 40 low- and middle-income countries. It is caused by Chlamydia trachomatis (Ct), a contagious intracellular bacterium. The World Health Organization
Externí odkaz:
https://doaj.org/article/f776565d7e4c48f2a78e7f3b10ecec19
Autor:
Jarrod T. Reilly, Simon B. Jäger, John Drew Wilson, John Cooper, Sebastian Eggert, Murray J. Holland
Publikováno v:
Physical Review Research, Vol 6, Iss 3, p 033090 (2024)
We present a simple and effective method to create highly entangled spin states on a faster timescale than that of the commonly employed one-axis twisting (OAT) model. We demonstrate that by periodically driving the Dicke Hamiltonian at a resonance f
Externí odkaz:
https://doaj.org/article/a6a37248ffa6452ba6f7a2b38eb03fff
Publikováno v:
Physical Review Research, Vol 6, Iss 3, p 033051 (2024)
Estimating a quantum phase is a necessary task in a wide range of fields of quantum science. To accomplish this task, two well-known methods have been developed in distinct contexts, namely, Ramsey interferometry (RI) in atomic and molecular physics
Externí odkaz:
https://doaj.org/article/0e3d51443c5d438eb06f317f350853e4
Autor:
Hanneke van derWijngaart, Sahil Jagga, Henk Dekker, Richard deGoeij, Sander R. Piersma, Thang V. Pham, Jaco C. Knol, Babs M. Zonderhuis, Harry J. Holland, Connie R. Jiménez, Henk M. W. Verheul, Srinivas Vanapalli, Mariette Labots
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10979-10989 (2023)
Abstract Purpose In precision oncology, tumor molecular profiles guide selection of therapy. Standardized snap freezing of tissue biospecimens is necessary to ensure reproducible, high‐quality samples that preserve tumor biology for adequate molecu
Externí odkaz:
https://doaj.org/article/cb94729eebe04cb6bb6590571fd04503
Physiological response after translocation differs between source populations in a threatened mammal
Autor:
Kelly S. Williams-Kelly, Laurence Berry, Kim Branch, Saul Cowen, Sean Garretson, Greg J. Holland, Rachel Ladd, Liberty Olds, Kelly Rayner, Colleen Sims, Leanne Van Der Weyde, Kylie A. Robert, Kerry V. Fanson
Publikováno v:
Royal Society Open Science, Vol 10, Iss 12 (2023)
Conservation translocations are an important tool in the prevention of species loss, but the translocation process is associated with numerous stressors. Non-invasively monitoring stress physiology via faecal glucocorticoid metabolites (FGMs) can pro
Externí odkaz:
https://doaj.org/article/583d4d08fd3f4719b1eac4b2d8443374
Autor:
Amber Barton, Nkoyo Faal, Athumani Ramadhani, Tamsyn Derrick, Elias Mafuru, Tara Mtuy, Patrick Massae, Aiweda Malissa, Hassan Joof, Pateh Makalo, Ansumana Sillah, Anna Harte, Harry Pickering, Robin Bailey, David Cw Mabey, Matthew J Burton, Martin J Holland
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 10, p e0011689 (2023)
BackgroundTrachoma is a neglected tropical disease caused by ocular infection with Chlamydia trachomatis, where repeated infections and chronic inflammation can ultimately result in scarring, trichiasis and blindness. While scarring is thought to be
Externí odkaz:
https://doaj.org/article/e8334fc389634c4f81e791bb17b2c840