Zobrazeno 1 - 10
of 245
pro vyhledávání: '"A J, Georges"'
Autor:
Sara T. Lo, Ronald H. L. Li, Catherine J. Georges, Nghi Nguyen, Cheyenne K. Chen, Claire Stuhlmann, Maureen Sigmund Oldach, Victor Noel Rivas, Samantha Fousse, Samantha P. Harris, Joshua A. Stern
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 4, Pp 1390-1400 (2023)
Abstract Background Dual antithrombotic treatment (DAT) with clopidogrel and rivaroxaban sometimes is prescribed to cats with hypertrophic cardiomyopathy at risk of thromboembolism. To date, no studies have evaluated their combined effects on platele
Externí odkaz:
https://doaj.org/article/37da3c77fb914dde8637aebb05fb0b69
Autor:
Vedran Vasic, Can Buldun, Manfred Ritz, Steffen Dickopf, Guy J. Georges, Christian Spick, Alessa Peuker, Thomas Meier, Klaus Mayer, Ulrich Brinkmann
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTAntibody-cytokine fusions targeted against tumor-associated antigens (TAAs) are promising cancer immunotherapy agents, with many such molecules currently undergoing clinical trials. However, due to the limited number of tumor-specific targets
Externí odkaz:
https://doaj.org/article/ee329adfb2144539ad1e235379420104
Akademický článek
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Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1221-1227 (2020)
Multispecific antibodies can be generated in different formats. More than two decades of R&D in the field of bispecific antibody engineering revealed that the design and choice of format can have a profound impact on the antibody functionality. This
Externí odkaz:
https://doaj.org/article/6d23cfca0fd1457390186925d84637a4
Autor:
Guy J. Georges, Stefan Dengl, Alexander Bujotzek, Friederike Hesse, Jens A.A. Fischer, Achim Gärtner, Jörg Benz, Matthias E. Lauer, Philippe Ringler, Henning Stahlberg, Friederike Plath, Ulrich Brinkmann, Sabine Imhof-Jung
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1210-1220 (2020)
The careful design of the antibody architecture is becoming more and more important, especially when the purpose is agonism. We present the design of a novel antibody format that is able to promote receptor dimerization and induce signal transduction
Externí odkaz:
https://doaj.org/article/e63a7374d4ac4858b91e6da04a61a06c
Autor:
T. LEPELLETIER, H. CHIÈZE, M. BERTRAND, T. BIENVENU, M. COUET, A. LISTER, J. GEORGES, A. SAINT-GERMAIN, P. KERHERVE, L. HASSIG
Publikováno v:
Techniques Sciences Méthodes. 12:105-119
Cet article présente une étude de cas pour évaluer les interactions entre un grand système d’assainissement et une crue entraînant des débordements, sur la base d’une modélisation hydraulique. L’étude de cas présentée ici est réalis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd09473623627d78fb2323d76950317c
https://doi.org/10.36904/202212105
https://doi.org/10.36904/202212105
Akademický článek
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Autor:
Benjamin D. Bice, Megan R. Stephens, Stephanie J. Georges, Ashlee R. Venancio, Peter C. Bermant, Annika V. Warncke, Kajsa E. Affolter, Julio R. Hidalgo, Melinda L. Angus-Hill
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 760-773 (2017)
Environmental enrichment (EE) replicates mind-body therapy by providing complex housing to laboratory animals to improve their activity levels, behavior, and social interactions. Using a Tcf4Het/+ ApcMin/+-mediated model of colon tumorigenesis, we fo
Externí odkaz:
https://doaj.org/article/8ff05c478fb2416696ab7ff0ede3bf9d
Publikováno v:
Journal of feline medicine and surgery, vol 24, iss 4
J Feline Med Surg
J Feline Med Surg
Objectives Feline arterial thromboembolism (ATE), an often devastating outcome, was recently shown to affect 11.3% of cats with hypertrophic cardiomyopathy over 10 years. Current American College of Veterinary Internal Medicine guidelines recommend t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8ea8d4891036aa513c051dc48c19a8
https://doi.org/10.1177/1098612x211013736
https://doi.org/10.1177/1098612x211013736
Autor:
Jean-Sébastien Hulot, Bernard Chevalier, Loic Belle, Guillaume Cayla, Khalife Khalife, François Funck, Romain Berthier, Christophe Piot, Muriel Tafflet, Gilles Montalescot, Loïc Belle, Hervé Le Breton, Emmanuel Teiger, Grégoire Dambrin, K. Khalife, L. Schmutz, F. Funck, R. Berthier, C. Piot, G. Hannebicque, G. Montalescot, T. Lognone, F. De Poli, B. Chevalier, N. Lhoest, M. Schneeberger, N. Delarche, A. Faure, H. Aelion, M. Godin, M. Gilard, B. Ritz, P. Barraud, P. Barnay, L.N. Saïdi, O. Le Dref, P. Garot, G. Range, J. Georges, C. Robin, Y. Cottin, L. Belle, G. Souteyrand, A. Lafont, A. Fournier, P. Dupouy, J. Shayne, P. Chapon, C. Boureux, J.P. Faure, H. Ben Amer, A. Furber, O. Ormezzano, G. Bayet, G. Karrillon, L. Maillard, A. Grenzinger, A. Avran, R. Koning, D. Dumant, X. Lamit, R. Dauphin, L. Drogoul, T. Cuisset, O. Wittenberg, J.P. Peyre, P. Laury, R. Robert
Publikováno v:
JACC: Cardiovascular Interventions. 13:621-630
@DrHulot_PARCC Anti-platelet therapy adjustment guided by CYP2C19 genotyping can be done in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f04ede21f166d59381f72be7a616d4e
https://doi.org/10.1016/j.jcin.2020.01.219
https://doi.org/10.1016/j.jcin.2020.01.219