The ClC-2 Chloride Channel Activator, Lubiprostone, Improves Intestinal Barrier Function in Biopsies from Crohn’s Disease but Not Ulcerative Colitis Patients

Autor: Young Su Park, Sang Bum Kang, Ronald R. Marchelletta, Harrison M. Penrose, Roos Ruiter-Visser, Barbara Jung, Michael J. Docherty, Brigid S. Boland, William J. Sandborn, Declan F. McCole

Publikováno v: Pharmaceutics, Vol 15, Iss 3, p 811 (2023)

The prostone analog, lubiprostone, is approved to manage constipation-predominant irritable bowel syndrome. Lubiprostone also protects intestinal mucosal barrier function in animal models of colitis. The aim of this study was to determine if lubipros

Externí odkaz: https://doaj.org/article/5f068f2b880b4b1ab6c054eb34c860c1

Epoxy-functional diblock copolymer spheres, worms and vesicles via polymerization-induced self-assembly in mineral oil

Autor: Matthew J. Derry, Philip J. Docherty, Steven P. Armes, Chloé Girou

Publikováno v: Polymer Chemistry. 11:3332-3339

Epoxy-functional diblock copolymer spheres, worms and vesicles are synthesized at 30% w/w solids via reversible addition–fragmentation chain transfer (RAFT) dispersion polymerization of glycidyl methacrylate (GlyMA) in mineral oil at 70 °C. This i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7964ce62ddfba82a7276bea3ef0a4c0
https://doi.org/10.1039/d0py00380h

Lecture capture as an element of the digital resource landscape - a qualitative study of flipped and non–flipped classrooms

Autor: Ross K. Galloway, C. J. Sangwin, Anna K. Wood, T. N. Bailey, P. J. Docherty, Judy Hardy

Publikováno v: Wood, A K, Bailey, T N, Galloway, R K, Hardy, J A, Sangwin, C J & Docherty, P J 2021, ' Lecture capture as an element of the digital resource landscape-a qualitative study of flipped and non–flipped classrooms ', Technology, Pedagogy and Education, pp. 1-16 . https://doi.org/10.1080/1475939X.2021.1917449

While it is increasingly common for live lectures to be recorded and made available online, there has been little exploration of how lecture capture usage fits within the wider context of digital resources available to students. Here the authors repo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0752ed1d89e1bd45a3f2840351eb50
https://hdl.handle.net/20.500.11820/2bf48ba0-9251-409e-b8e4-147cc012829e

Transience and Timelessness: The Origins and Afterlife of Augustus Saint-Gaudens’s Portrait of Robert Louis Stevenson

Autor: Linda J. Docherty

Publikováno v: Nineteenth-Century Art Worldwide. 19

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b66139255a56cae92755429d71a092e
https://doi.org/10.29411/ncaw.2020.19.1.4

AMPK mediates inhibition of electrolyte transport and NKCC1 activity by reactive oxygen species

Autor: Michael Scharl, Alfred E. Chappell, Michael Bunz, Declan F. McCole, Barbara H. Jung, Stephanie J. King, Christian Lytle, Michael J. Docherty

Publikováno v: American journal of physiology. Gastrointestinal and liver physiology, vol 317, iss 2
Am J Physiol Gastrointest Liver Physiol

Reactive oxygen species such as H2O2are believed to play a prominent role in the injury and loss of transport function that affect the intestinal epithelium in inflammatory conditions such as inflammatory bowel diseases. Defects in intestinal epithel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f65f6f35a8f2fa31975e2fdafc3c50
https://escholarship.org/uc/item/8mm317rc