Výsledky vyhledávání - "A J, Denisuik"

Dramatic rise in the proportion of ESBL-producing Escherichia coli and Klebsiella pneumoniae among clinical isolates identified in Canadian hospital laboratories from 2007 to 2016

Autor: James A. Karlowsky, Daryl J. Hoban, Heather J. Adam, Michael R. Mulvey, Andrew J Denisuik, George G. Zhanel, Canward, Philippe Lagacé-Wiens, Melanie R. Baxter

Publikováno v: Journal of Antimicrobial Chemotherapy. 74:iv64-iv71

Objectives To assess the prevalence, antimicrobial susceptibilities and molecular characteristics of ESBL-producing Escherichia coli and Klebsiella pneumoniae infecting patients receiving care in Canadian hospitals from January 2007 to December 2016.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e9c81f6f164cfe1e2b2345241bf802
https://doi.org/10.1093/jac/dkz289

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42936 pathogens from Canadian hospitals: 10 years of results (2007–16) from the CANWARD surveillance study

Autor: Andrew Walkty, George G. Zhanel, Daryl J. Hoban, Philippe Lagacé-Wiens, Heather J. Adam, James A. Karlowsky, Michael R. Mulvey, Rachel Hink, Canward, Alyssa R Golden, Denice C. Bay, Andrew J Denisuik, Jeff Fuller, Melanie R. Baxter, Frank Schweizer, Kimberly A. Nichol

Publikováno v: Journal of Antimicrobial Chemotherapy. 74:iv5-iv21

Objectives The CANWARD surveillance study was established in 2007 to annually assess the in vitro susceptibilities of a variety of antimicrobial agents against bacterial pathogens isolated from patients receiving care in Canadian hospitals. Methods 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7143a982a2ba36810d6e05bd6235fd3c
https://doi.org/10.1093/jac/dkz283

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ESBL-positive Escherichia coli and Klebsiella pneumoniae isolates from across Canada: CANWARD surveillance study, 2007-18

Autor: George G. Zhanel, Heather J. Adam, Andrew J Denisuik, Alyssa R Golden, Melanie R. Baxter, Michael R. Mulvey, Andrew Walkty, James A. Karlowsky, Melissa McCracken

Publikováno v: The Journal of antimicrobial chemotherapy. 76(11)

Objectives ESBL-producing Escherichia coli and Klebsiella pneumoniae are pathogens of increasing importance in Canada and elsewhere in the world. The purpose of this study was to phenotypically and molecularly characterize ESBL-producing E. coli and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f696707c44015288754a7f600e1bc96c
https://pubmed.ncbi.nlm.nih.gov/34378029

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Comparison of phenotypic antimicrobial susceptibility testing results and WGS-derived genotypic resistance profiles for a cohort of ESBL-producing Escherichia coli collected from Canadian hospitals: CANWARD 2007-18

Autor: Melanie R. Baxter, George G. Zhanel, Denice C. Bay, Andrew J Denisuik, Alyssa R Golden, James A. Karlowsky, Heather J. Adam, Michael R. Mulvey, Andrew Walkty, Melissa McCracken

Publikováno v: The Journal of antimicrobial chemotherapy. 76(11)

Objectives To determine whether the genotypic resistance profile inferred from WGS could accurately predict phenotypic resistance for ESBL-producing Escherichia coli isolated from patient samples in Canadian hospital laboratories. Methods As part of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62d8c55c59201711fcee2cbf0e3b120
https://pubmed.ncbi.nlm.nih.gov/34378044

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Antimicrobial-resistant pathogens in Canadian ICUs: results of the CANWARD 2007 to 2016 study

Autor: Melanie R. Baxter, Kimberly A. Nichol, Daryl J. Hoban, Alyssa R Golden, Michael R. Mulvey, Lauren A Garbutt, Andrew J Denisuik, James A. Karlowsky, Andrew Walkty, Philippe Lagacé-Wiens, Heather J. Adam, George G. Zhanel

Publikováno v: Journal of Antimicrobial Chemotherapy. 74:645-653

OBJECTIVES To describe the microbiology and antimicrobial resistance patterns of cultured samples acquired from Canadian ICUs. METHODS From 2007 to 2016, tertiary care centres from across Canada submitted 42938 bacterial/fungal isolates as part of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0356ed8143f94e660adeb579992aa3c
https://doi.org/10.1093/jac/dky477

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Trends in antimicrobial resistance over 10 years among key bacterial pathogens from Canadian hospitals: results of the CANWARD study 2007-16

Autor: Alyssa R Golden, Philippe Lagacé-Wiens, George G. Zhanel, Daryl J. Hoban, George R. Golding, Michael R. Mulvey, Kimberly A. Nichol, Andrew J Denisuik, Melanie R. Baxter, James A. Karlowsky, Andrew Walkty, Susan M. Poutanen, Heather J. Adam, Canward

Publikováno v: The Journal of antimicrobial chemotherapy. 74(Suppl 4)

ObjectivesWe sought to analyse 10 years of longitudinal surveillance data (2007–16) from the CANWARD study and describe emerging trends in antimicrobial resistance for key bacterial pathogens across Canada.MethodsLongitudinal data from CANWARD stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a441cb2b77cf486bf321f322c2f2bea
https://pubmed.ncbi.nlm.nih.gov/31505648

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In Vitro Activity of Sulopenem, an Oral Penem, against Urinary Isolates of Escherichia coli

Autor: Heather J. Adam, Michael W. Dunne, Andrew J Denisuik, George G. Zhanel, Philippe Lagacé-Wiens, Sailaja Puttagunta, Andrew Walkty, Melanie R. Baxter, James A. Karlowsky

The in vitro activity of sulopenem was assessed against a collection from 2014 to 2016 of 539 urinary isolates of Escherichia coli from Canadian patients by using CLSI-defined broth microdilution methodology. A concentration of sulopenem 0.03 µg/ml

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9c349725be2913c48a035f708ef1ce
https://europepmc.org/articles/PMC6325175/

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Pharmacodynamic activity of ertapenem versus genotypically characterized extended-spectrum -lactamase (ESBL)-, KPC- or NDM-producing Escherichia coli with reduced susceptibility or resistance to ertapenem using an in vitro model

Autor: Heather J. Adam, Daryl J. Hoban, Andrew J Denisuik, Shivangi Vashisht, Chris Yachison, George G. Zhanel

Publikováno v: Journal of Antimicrobial Chemotherapy. 69:2448-2452

OBJECTIVES We assessed the pharmacodynamic activity of ertapenem against Escherichia coli with reduced susceptibility (MIC 0.12-0.5 mg/L), intermediate resistance (MIC 1.0 mg/L) or resistance (MIC ≥ 2 mg/L) to ertapenem using an in vitro model. MET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5748871d97965963103f6e4faf30e9f0
https://doi.org/10.1093/jac/dku149

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